Induction of WAF1/CIP1 by a p53-independent Pathway

Cancer Research

Volumn 54, Issue 13, 1994, Pages 3391-3395

  Lin, David ^b   Mercer, W Edward ^b   Pierce, Jacalyn H ^a   Givol, David ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN P53;

ANIMAL CELL; ARTICLE; CANCER GENETICS; CELL CYCLE; DNA DAMAGE; EMBRYO; FIBROBLAST CULTURE; GENE INDUCTION; IMMEDIATE EARLY GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CYCLOHEXIMIDE; G1 PHASE; GENE EXPRESSION REGULATION; GENES, IMMEDIATE-EARLY; GENES, P53; GENES, TUMOR SUPPRESSOR; GROWTH SUBSTANCES; INSULIN; MICE; MOLECULAR SEQUENCE DATA; PLATELET-DERIVED GROWTH FACTOR; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0028236846     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Lau, L.F., and Nathans, D. Genes induced by serum growth factors. In: P. Cohen and T.G. Foulkes (eds.), The Hormonal Control of Gene Transcription, pp. 257-293. New York: Elsevier Science Publishers, 1991.
2. Hunter, T. Braking the cycle. Cell, 75: 839-841, 1993.
3. Sherr, C.J. Mammalian G, cyclins. Cell, 73: 1059-1065, 1993.
4. Lin, D., Shields, M.T., Ullrich, S.J., Appella, E., and Mercer, W.E. Growth arrest induced by wild-type p. 3 protein blocks cells prior to or near the restriction point in late G, phase. Proc. Natl. Acad. Sci. USA, 89: 9210-9214, 1992.
5. Kastan, M.B., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R.W. Participation of p. 3 protein in the cellular response to DNA damage. Cancer Res., 51: 6304-6311, 1991.
6. Kuerbitz, S.J., Plunkett, B.S., Walsh, W.V., and Kastan, M.B. Wild-type p. 3 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
7. Kastan, M.B., Zhan, Q., El-Deiry, W., Carrier, F., Jacks, T., Walsh, W.V., Plunkett, B.S., and Fornace, A.J., Jr. A mammalian cell cycle checkpoint pathway utilizing p. 3 and GADD45 is defective in ataxia-telangiectasia. Cell, 71: 587-597, 1992.
8. Lane, D.P. p. 3, the guardian of the genome. Nature (Lond.), 358: 15-16, 1992.
9. El-Deiry, W., Tokino, T., Velculescu, V.E., Levy, D.B., Parsons, R., Trent, J.M., Un, D., Mercer, W.E., Kinzler, K.W., and Vogelstein, B. WAF1, a potential mediator of p. 3 tumor suppression. Cell, 75: 817-825, 1993.
10. Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K., and Elledge, S.J. The p. 1 Cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75: 805-816, 1993.
11. Xiong, Y., Hannon, G.J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. p. 1 is a universal inhibitor of cyclin kinases. Nature (Lond.), 366: 701-704, 1993.
12. El-Deiry, W., Harper, J.W., O'Connor, P.M., et al. WAF1/CIP1 is induced in p. 3-mediated G, arrest and apoptosis. Cancer Res., 54: 1169-1174, 1994.
13. Livingstone, L.R., White, A., Sprouse, J., Livanos, E., Jacks, T., and Tlsty, T. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p. 3. Cell, 70: 923-935, 1992.
14. Mercer, W.E., Shields, M.T., Amin, M., Sauve, G.J., Appella, E., Romano, J.W., and Ullrich, S.J. Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-tame p. 3. Proc. Natl. Acad. Sci. USA, 87: 6166-6170, 1990.
15. Sambrook, J., Fritsch, E.F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
16. Harvey, M., Sands, A.T., Weiss, R.S., Hegi, M.E., Wiseman, R.W., Pantazis, P., Giovannella, B.C., Tainsky, M.A., Bradley, A., and Donehower, L.A. In vitro growth characteristics of embryo fibroblasts isolated from p. 3-deficient mice. Oncogene, 8: 2457-2467, 1993.
17. Aaronson, S.A. Growth factors and cancer. Science (Washington DC), 254: 1146-1153, 1991.
18. Noda, A., Ning, Y., Venable, S.F., Pereira-Smith, O.M., and Smith, J.R. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res., 211: 90-98, 1994.
19. Polyak, K., Kato, J.Y., Solomon, M.J., Sherr, C.J., Massague, J., Roberts, J.M., and Koff, A. p. 7Kip1 a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8: 9-22, 1994.
20. Lowe, S.W., Ruley, H.E., Jacks, T., and Housman, D.E. p. 3-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957-967, 1993.