The reversible DNA-alkylating activity of duocarmycin and its analogues

Nucleic Acids Research

Volumn 22, Issue 1, 1994, Pages 88-93

  Asai, Akira ^a   Nagamura, Satoru ^a   Saito, Hiromitsu ^a   Takahashi, Isami ^a   Nakano, Hirofumi ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG ANALOG; DUOCARMYCIN A;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS; BACTERIAL GROWTH; CONTROLLED STUDY; DNA ADDUCT; DNA ALKYLATION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; DRUG RELEASE; DRUG STRUCTURE; GROWTH INHIBITION; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NONHUMAN; OSMOLARITY; PH; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ALKYLATING AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA DAMAGE; IN VITRO; NUCLEIC ACID CONFORMATION; PYRROLIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS);

EID: 0028236007     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/22.1.88     Document Type: Article

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