Evaluation of methotrexate tissue exposure by in situ microdialysis in a rat model

Cancer Chemotherapy and Pharmacology

Volumn 34, Issue 4, 1994, Pages 297-301

  Ekstrøm, Per O ^a   Andersen, Anders ^a   Warren, David J ^a   Giercksky, Karl E ^a   Slørdal, Lars ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Methotrexate; Microdialysis; Rat; Tissue

Indexed keywords

7 HYDROXYMETHOTREXATE; DRUG METABOLITE; METHOTREXATE;

ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; LIVER; MALE; MICRODIALYSIS; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; TECHNIQUE;

ANIMAL; EXTRACELLULAR SPACE; FEASIBILITY STUDIES; INFUSIONS, INTRAVENOUS; MALE; METHOTREXATE; MICRODIALYSIS; MONITORING, PHYSIOLOGIC; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; TISSUE DISTRIBUTION;

EID: 0028234411     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/BF00686036     Document Type: Article

References (13)

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