Non-invasive determination of tumor oxygen tension and local variation with growth

International Journal of Radiation Oncology, Biology, Physics

Volumn 29, Issue 1, 1994, Pages 95-103

  Mason, Ralph P ^a   Antich, Peter P ^a   Babcock, Evelyn E ^a   Constantinescu, Anca ^a   Peschke, Peter ^b   Hahn, Eric W ^b  

^a Department of Radiology UT Southwestern Medical Center Dallas TX Germany ^*  (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

19F NMR; MRI; Perfluorocarbon; pO2; Prostate tumor

Indexed keywords

FLUOROCARBON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER TRANSPLANTATION; HYPOXIA; MALE; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TISSUE DISTRIBUTION;

ADENOCARCINOMA; ANIMAL; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; OXYGEN; PROSTATIC NEOPLASMS; RATS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028224408     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(94)90231-3     Document Type: Article

References (58)

1. Correlation between oxygen tension and spin lattice relaxation rate in tumors
2. Perfluorooctyl bromide as a contrast agent for CT and sonography: Preliminary clinical results
3. 9F NMR
4. 9F NMR
5. Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy
6. Evidence for intermittent radiobiological hypoxia in experimental tumor systems
7. Hypoxia in tumors: A paradigm for the approach to biochemical and physiological heterogeneity
8. Tumor detection by NMR
9. Physiological hypoxia and its influence on radiotherapy
10. 9F NMR imaging of blood oxygenation in the brain
11. The Effect of Oxygen Breathing and Radiotherapy upon the Tissue Oxygen Tension of some Human Tumours
12. 1 measurements in inhomogeneous B, with surface coils
13. In vivo measurements of vascular oxygen tension in tumors using MRI of a fluorinated blood substitute
14. Oxygen distribution in squamous cell carcinoma metastases and its relationship to the outcome of radiation therapy
15. The Concentration of Oxygen Dissolved in Tissues at the Time of Irradiation as a Factor in Radiotherapy
16. Monitoring cancer therapy by NMR spectroscopy
17. Isolated tumor growth in a surgically formed skin pedicle in the rat: A new tumor model for NMR studies
18. 9F NMR relaxometry of a perfluorocarbon emulsion
19. Animal models of the hormone-sensitive and-insensitive prostatic adeno-carcinomas, Dunning R3327-H, R3327-HI and R-3327-AT
20. Reduction of myo cardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol
21. 19F magnetic resonance spectroscopy and immunohistochemistry
22. The oxygenation of murine tumor isografts and human tumor xenografts by nicotinamide. Radiat
23. Temperature relationships of proton spin lattice times in biological tissue. Bull
24. 9F NMR
25. 9F NMR of perfluorocarbons
26. 9F MRI study in tumor bearing mice
27. 9F MRI: Molecule specific imaging
28. 9F surface coil NMR spectroscopy of sequestered perfluorocarbon emulsion
29. Tumor oxygen tension gradients: New evidence from '9F MRI of perfluorocarbons (Abstr.)
30. Oxygent: A novel probe of tissue oxygen tension
31. 19F NMR spectroscopy of perfluorocarbon
32. 9F magnetic resonance spectroscopy in vivo
33. Hypoxic fractions of solid tumors, experimental technique, methods of analysis and a survey of existing data
34. Pathophysiological approaches to identifying tumor hypoxia in patients
35. Fluosol adjuvant therapy in human cancer: Examinations in vivo of perfluorocarbons by F-19 NMR (Abstr.)
36. 31P NMR
37. 31P MRS: Correlation of longitudinal relaxation with tumor growth rate and DNA synthesis
38. Response of the rat Dunning R3327 AT 1 prostate tumor to treatment with fractionated fast neutrons
39. 13P NMR spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglo bin saturation status and tumor hypoxia
40. Interstitial hypertension in carcinoma of the cervix in patients: Possible correlation with tumor oxygenation and radiation response
41. A clinical trial of Fluosol DA 20% in advanced squamous cell carcinoma of the head and neck
42. 2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen
43. Evaluation of BAA 1112 rhabdo-myosarcoma oxygenation with microelectrodes, optical spectrometry, radiosensitivity, and magnetic resonance spectroscopy
44. 31P MR spectroscopy
45. 31P magnetic resonance spectroscopy is sensitive to tumor hypoxia: Perfusion and oxygenation of rat 9L gliosarcoma after treatment with BCNU
46. 31P NMR spectroscopic and near infrared spectrophotometric studies of effects of an esthetics on in vivo RIF-1 tumors
47. Radiation sensitizers and bioreductive drugs
48. Cell and environmental interaction in tumor microregions
49. The biomedical application of fluorine-19 NMR
50. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells
51. The radiation sensitivities of AT3327-H and R3327-AT1 rat prostate adenocarcinomas
52. 2 cellular level
53. Driven equilibrium radio-frequency pulses in NMR imaging
54. 2 saturation in malignant tumors during normoxia and hyperoxia
55. 2 in a murine fibrosarcoma
56. 2 tension measurements
57. Oxygenation effect of Fluosol on hypoxic tumor tissue and retention of PFCs in the tumor bearing rats