Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nature

Volumn 368, Issue 6474, 1994, Pages 856-859

  Lonberg, Nils ^a   Taylor, Lisa D ^a   Harding, Fiona A ^a   Trounstine, Mary ^a   Higgins, Kay M ^a   Schramm, Stephen R ^a   Kuo, Chiung Chi ^a   Mashayekh, Roshanak ^a   Wymore, Kathryn ^a   McCabe, James G ^a   Munoz O'Regan, Donna ^a   O'Donnell, Susan L ^a   Lapachet, Elizabeth S G ^a   Bengoechea, Tasha ^a   Fishwild, Dianne M ^a   Carmack, Condie E ^a   Kay, Robert M ^a   Huszar, Dennis ^a  

^a GenPharm International   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; HUMAN; HYBRIDOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; B-LYMPHOCYTES; BASE SEQUENCE; BONE MARROW CELLS; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; HUMAN; HYBRIDOMAS; IMMUNOGLOBULIN E; IMMUNOGLOBULINS, HEAVY-CHAIN; IMMUNOGLOBULINS, LIGHT-CHAIN; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; OLIGODEOXYRIBONUCLEOTIDES; PERITONEAL CAVITY; SPLEEN; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028222932     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/368856a0     Document Type: Article

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