Topiramate: Preclinical Evaluation of a Structurally Novel Anticonvulsant

Epilepsia

Volumn 35, Issue 2, 1994, Pages 450-460

  Shank, Richard P ^a   Gardocki, Joseph F ^a   Vaught, Jeffry L ^a   Davis, Coralie B ^a   Schupsky, James J ^a   Raffa, Robert B ^a   Dodgson, Susanna J ^b   Nortey, Samuel O ^a   Maryanoff, Bruce E ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Anticonvulsant; Carbamazepine; Drug toxicity; Phenytoin; Topiramate

Indexed keywords

4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; ACETAZOLAMIDE; ANTICONVULSIVE AGENT; BICUCULLINE; CARBAMAZEPINE; CARBONATE DEHYDRATASE; FLUNARIZINE; ION CHANNEL; NEUROTRANSMITTER; PENTETRAZOLE; PHENOBARBITAL; PHENYTOIN; PICROTOXIN; PROADIFEN; RESERPINE; TETRABENAZINE; TOPIRAMATE; VALPROIC ACID; VERATRIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CROSS TOLERANCE; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG SCREENING; ELECTRIC SHOCK; ERYTHROCYTE; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR DYSFUNCTION; MOUSE; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SEIZURE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMAL; ANTICONVULSANTS; DRUG INTERACTIONS; ELECTROSHOCK; FRUCTOSE; MALE; MICE; MOLECULAR STRUCTURE; PENTYLENETETRAZOLE; PICROTOXIN; RATS; RATS, WISTAR; RESERPINE; SEIZURES; TETRABENAZINE;

EID: 0028221989     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1994.tb02459.x     Document Type: Article

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