메뉴 건너뛰기




Volumn 14, Issue 5, 1994, Pages 2883-2894

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHOSPHATIDYLINOSITOL KINASE; PROTEIN TYROSINE KINASE;

EID: 0028212411     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.14.5.2883     Document Type: Article
Times cited : (159)

References (61)
  • 2
    • 0025681492 scopus 로고
    • Binding of SH2 domains of phospholipase Cγ1, GAP, and src to activated growth factor receptors
    • Anderson, D., C. A. Koch, L. Grey, C. Ellis, M. F. Moran, and T. Pawson. 1990. Binding of SH2 domains of phospholipase Cγ1, GAP, and src to activated growth factor receptors. Science 250: 979-982.
    • (1990) Science , vol.250 , pp. 979-982
    • Anderson, D.1    Koch, C.A.2    Grey, L.3    Ellis, C.4    Moran, M.F.5    Pawson, T.6
  • 4
    • 0026658116 scopus 로고
    • Tyrosine phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze crk-phosphotyrosine-dependent interactions in vitro
    • Birge, R. B., J. E. Fajardo, B. J. Mayer, and H. Hanafusa. 1992. Tyrosine phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze crk-phosphotyrosine-dependent interactions in vitro. J. Biol. Chem. 267:10588-10595.
    • (1992) J. Biol. Chem. , vol.267 , pp. 10588-10595
    • Birge, R.B.1    Fajardo, J.E.2    Mayer, B.J.3    Hanafusa, H.4
  • 5
    • 0026743906 scopus 로고
    • Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho
    • Cicchetti, P., B. J. Mayer, G. Thiel, and D. Baltimore. 1992. Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science 257:803-806.
    • (1992) Science , vol.257 , pp. 803-806
    • Cicchetti, P.1    Mayer, B.J.2    Thiel, G.3    Baltimore, D.4
  • 6
    • 85053099623 scopus 로고
    • The src family of protein-tyrosine kinases
    • B. Kemp and P. F. Alewood (ed.), CRC Press, Boca Raton, Fla.
    • Cooper, J. A. 1990. The src family of protein-tyrosine kinases, p. 85-113. In B. Kemp and P. F. Alewood (ed.), Peptides and protein phosphorylation. CRC Press, Boca Raton, Fla.
    • (1990) Peptides and Protein Phosphorylation , pp. 85-113
    • Cooper, J.A.1
  • 7
    • 0027300619 scopus 로고
    • The when and how of Src regulation
    • Cooper, J. A., and B. Howell. 1993. The when and how of Src regulation. Cell 73:1051-1054.
    • (1993) Cell , vol.73 , pp. 1051-1054
    • Cooper, J.A.1    Howell, B.2
  • 8
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210 bcr/abl gene of the Philadelphia chromosome
    • Daley, G. Q., R. A. Van Etten, and D. Baltimore. 1990. Induction of chronic myelogenous leukemia in mice by the P210 bcr/abl gene of the Philadelphia chromosome. Science 247:824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 9
    • 0025727594 scopus 로고
    • cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor
    • Escobedo, J. A., S. Navankasattusas, W. M. Kavanaugh, D. Milfay, V. A. Fried, and L. T. Williams. 1991. cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor. Cell 65:75-82.
    • (1991) Cell , vol.65 , pp. 75-82
    • Escobedo, J.A.1    Navankasattusas, S.2    Kavanaugh, W.M.3    Milfay, D.4    Fried, V.A.5    Williams, L.T.6
  • 10
    • 0022391165 scopus 로고
    • Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus
    • Foulkes, J. G., M. Chow, C. Gorka, A. R. Frackelton, Jr., and D. Baltimore. 1985. Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus. J. Biol. Chem. 260:8070-8077.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8070-8077
    • Foulkes, J.G.1    Chow, M.2    Gorka, C.3    Frackelton Jr., A.R.4    Baltimore, D.5
  • 11
    • 0024461553 scopus 로고
    • Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential
    • Franz, W. M., P. Berger, and J. Y. J. Wang. 1989. Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential. EMBO J. 8:137-147.
    • (1989) EMBO J. , vol.8 , pp. 137-147
    • Franz, W.M.1    Berger, P.2    Wang, J.Y.J.3
  • 12
  • 13
    • 0019127191 scopus 로고
    • Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA
    • Gott, S. P., E. Gilboa, O. N. Witte, and D. Baltimore. 1980. Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA. Cell 22:777-785.
    • (1980) Cell , vol.22 , pp. 777-785
    • Gott, S.P.1    Gilboa, E.2    Witte, O.N.3    Baltimore, D.4
  • 14
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phytogeny of the catalytic domains
    • Hanks, S. K., A. M. Quinn, and T. Hunter. 1988. The protein kinase family: conserved features and deduced phytogeny of the catalytic domains. Science 241:42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 15
    • 0026074818 scopus 로고
    • Cooperation between oncogenes
    • Hunter, T. 1991. Cooperation between oncogenes. Cell 64:249-270.
    • (1991) Cell , vol.64 , pp. 249-270
    • Hunter, T.1
  • 16
    • 0024343691 scopus 로고
    • N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl
    • Jackson, P., and D. Baltimore. 1989. N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl. EMBO J. 8:449-456.
    • (1989) EMBO J. , vol.8 , pp. 449-456
    • Jackson, P.1    Baltimore, D.2
  • 18
    • 0027185806 scopus 로고
    • Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl
    • Jackson, P. K., M. Paskind, and D. Baltimore. 1993. Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Oncogene 8:1943-1956.
    • (1993) Oncogene , vol.8 , pp. 1943-1956
    • Jackson, P.K.1    Paskind, M.2    Baltimore, D.3
  • 20
    • 0024435446 scopus 로고
    • The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function
    • Koch, C. A., M. F. Moran, I. Sadowski, and T. Pawson. 1989. The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function. Mol. Cell. Biol. 9:4131-4140.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4131-4140
    • Koch, C.A.1    Moran, M.F.2    Sadowski, I.3    Pawson, T.4
  • 21
    • 0021236375 scopus 로고
    • Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity
    • Konopka, J. B., R. L. Davis, S. M. Watanabe, A. S. Ponticelli, L. Schiff-Maker, N. Rosenberg, and O. N. Witte. 1984. Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity. J. Virol. 51:223-232.
    • (1984) J. Virol. , vol.51 , pp. 223-232
    • Konopka, J.B.1    Davis, R.L.2    Watanabe, S.M.3    Ponticelli, A.S.4    Schiff-Maker, L.5    Rosenberg, N.6    Witte, O.N.7
  • 25
    • 0025978644 scopus 로고
    • Identification of domains of the v-crk oncogens product sufficient for association with phosphotyrosine-containing proteins
    • Matsuda, M., B. J. Mayer, and H. Hanafusa. 1991. Identification of domains of the v-crk oncogens product sufficient for association with phosphotyrosine-containing proteins. Mol. Cell. Biol. 11: 1607-1613.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1607-1613
    • Matsuda, M.1    Mayer, B.J.2    Hanafusa, H.3
  • 26
    • 0027507115 scopus 로고
    • Signalling through SH2 and SH3 domains
    • Mayer, B. J., and D. Baltimore. 1993. Signalling through SH2 and SH3 domains. Trends Cell Biol. 3:8-13.
    • (1993) Trends Cell Biol. , vol.3 , pp. 8-13
    • Mayer, B.J.1    Baltimore, D.2
  • 28
    • 0026059615 scopus 로고
    • The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity
    • Mayer, B. J., P. K. Jackson, and D. Baltimore. 1991. The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity. Proc. Natl. Acad. Sci. USA 88:627-631.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 627-631
    • Mayer, B.J.1    Jackson, P.K.2    Baltimore, D.3
  • 29
    • 0026601293 scopus 로고
    • Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo
    • Mayer, B. J., P. K. Jackson, R. A. Van Etten, and D. Baltimore. 1992. Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Mol. Cell. Biol. 12:609-618.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 609-618
    • Mayer, B.J.1    Jackson, P.K.2    Van Etten, R.A.3    Baltimore, D.4
  • 30
    • 0027212082 scopus 로고
    • How receptors turn ras on
    • McCormick, F. 1993. How receptors turn ras on. Nature (London) 363:15-16.
    • (1993) Nature (London) , vol.363 , pp. 15-16
    • McCormick, F.1
  • 32
    • 0024991898 scopus 로고
    • pEF-BOS, a powerful mammalian expression vector
    • Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5322
    • Mizushima, S.1    Nagata, S.2
  • 34
    • 0027520893 scopus 로고
    • En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein-tyrosine kinase
    • Muller, A. J., A. M. Pendergast, K. Parmar, M. H. Havlik, N. Rosenberg, and O. N. Witte. 1993. En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein-tyrosine kinase. Proc. Natl. Acad. Sci. USA 90:3457-3461.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3457-3461
    • Muller, A.J.1    Pendergast, A.M.2    Parmar, K.3    Havlik, M.H.4    Rosenberg, N.5    Witte, O.N.6
  • 35
    • 0025959660 scopus 로고
    • BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias
    • Muller, A. J., J. C. Young, A. M. Pendergast, M. Pondel, N. Landau, D. R. Littman, and O. N. Witte. 1991. BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias. Mol. Cell. Biol. 11:1785-1792.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1785-1792
    • Muller, A.J.1    Young, J.C.2    Pendergast, A.M.3    Pondel, M.4    Landau, N.5    Littman, D.R.6    Witte, O.N.7
  • 36
    • 0027570012 scopus 로고
    • The assembly of signalling complexes by receptor tyrosine kinases
    • Panayotou, G., and M. D. Waterfield. 1993. The assembly of signalling complexes by receptor tyrosine kinases. Bioessays 15: 171-177.
    • (1993) Bioessays , vol.15 , pp. 171-177
    • Panayotou, G.1    Waterfield, M.D.2
  • 37
    • 0026484261 scopus 로고
    • SH2 and SH3 domains: From structure to function
    • Pawson, T., and G. Gish. 1992. SH2 and SH3 domains: from structure to function. Cell 71:359-362.
    • (1992) Cell , vol.71 , pp. 359-362
    • Pawson, T.1    Gish, G.2
  • 38
    • 0026639821 scopus 로고
    • Triggering signalling cascades by receptor tyrosine kinases
    • Pazin, M. J., and L. T. Williams. 1992. Triggering signalling cascades by receptor tyrosine kinases. Trends Biochem. Sci. 17: 374-378.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 374-378
    • Pazin, M.J.1    Williams, L.T.2
  • 39
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W. S., G. P. Nolan, M. L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA 90:8392-8396.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 41
    • 0020158951 scopus 로고
    • In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog
    • Ponticelli, A. S., C. A. Whitlock, N. Rosenberg, and O. N. Witte. 1982. In vivo tyrosine phosphorylations of the abelson virus transforming protein are absent in its normal cellular homolog. Cell 29:953-960.
    • (1982) Cell , vol.29 , pp. 953-960
    • Ponticelli, A.S.1    Whitlock, C.A.2    Rosenberg, N.3    Witte, O.N.4
  • 42
    • 0024165855 scopus 로고
    • c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95
    • c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95. Oncogene Res. 3:343-355.
    • (1988) Oncogene Res. , vol.3 , pp. 343-355
    • Potts, W.M.1    Reynolds, A.B.2    Lansing, T.J.3    Parsons, J.T.4
  • 43
    • 0026895954 scopus 로고
    • The product of the cellular crk gene consists primarily of SH2 and SH3 regions
    • Reichman, C. T., B. J. Mayer, S. Keshav, and H. Hanafusa. 1992. The product of the cellular crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ. 3:451-460.
    • (1992) Cell Growth Differ. , vol.3 , pp. 451-460
    • Reichman, C.T.1    Mayer, B.J.2    Keshav, S.3    Hanafusa, H.4
  • 45
    • 0027408247 scopus 로고
    • Identification of a 10-amino acid proline-rich SH3 binding site
    • Ren, R., B. J. Mayer, P. Cicchetti, and D. Baltimore. 1993. Identification of a 10-amino acid proline-rich SH3 binding site. Science 259:1157-1161.
    • (1993) Science , vol.259 , pp. 1157-1161
    • Ren, R.1    Mayer, B.J.2    Cicchetti, P.3    Baltimore, D.4
  • 46
    • 0026739538 scopus 로고
    • Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context
    • Renshaw, M. W., E. T. Kipreos, M. R. Albrecht, and J. Y. J. Wang. 1992. Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth, depending on the cell context. EMBO J. 11:3941-3951.
    • (1992) EMBO J. , vol.11 , pp. 3941-3951
    • Renshaw, M.W.1    Kipreos, E.T.2    Albrecht, M.R.3    Wang, J.Y.J.4
  • 48
    • 0026567491 scopus 로고
    • SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: Identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase Cγ
    • Rotin, D., B. Margolis, M. Mohammadi, R. J. Daly, G. Daum, N. Li, E. H. Fischer, W. H. Burgess, A. Ullrich, and J. Schlessinger. 1992. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase Cγ. EMBO J. 11:559-567.
    • (1992) EMBO J. , vol.11 , pp. 559-567
    • Rotin, D.1    Margolis, B.2    Mohammadi, M.3    Daly, R.J.4    Daum, G.5    Li, N.6    Fischer, E.H.7    Burgess, W.H.8    Ullrich, A.9    Schlessinger, J.10
  • 50
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger, J., and A. Ullrich. 1992. Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 51
    • 0026572318 scopus 로고
    • Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src
    • Seidel-Dugan, C., B. E. Meyer, S. M. Thomas, and J. S. Brugge. 1992. Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src. Mol. Cell. Biol. 12:1835-1845.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1835-1845
    • Seidel-Dugan, C.1    Meyer, B.E.2    Thomas, S.M.3    Brugge, J.S.4
  • 52
    • 0021802841 scopus 로고
    • Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
    • Shtivelman, E., B. Lifshitz, R. P. Gale, and E. Canaani. 1985. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature (London) 315:550-554.
    • (1985) Nature (London) , vol.315 , pp. 550-554
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Canaani, E.4
  • 53
    • 0023806075 scopus 로고
    • Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
    • Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
    • (1988) Gene , vol.67 , pp. 31-40
    • Smith, D.B.1    Johnson, K.S.2
  • 55
    • 0027182279 scopus 로고
    • Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src
    • Superti-Furga, G., S. Fumagalli, M. Koegl, S. A. Courtneidge, and G. Draetta. 1993. Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src. EMBO J. 12:2625-2634.
    • (1993) EMBO J. , vol.12 , pp. 2625-2634
    • Superti-Furga, G.1    Fumagalli, S.2    Koegl, M.3    Courtneidge, S.A.4    Draetta, G.5
  • 57
    • 0027211693 scopus 로고
    • Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
    • Valius, M., and A. Kazlauskas. 1993. Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73:321-334.
    • (1993) Cell , vol.73 , pp. 321-334
    • Valius, M.1    Kazlauskas, A.2
  • 58
    • 84901968755 scopus 로고    scopus 로고
    • Personal communication
    • Van Etten, R. Personal communication.
    • Van Etten, R.1
  • 59
    • 0024353722 scopus 로고
    • The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
    • Van Etten, R. A., P. Jackson, and D. Baltimore. 1989. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell 58:669-678.
    • (1989) Cell , vol.58 , pp. 669-678
    • Van Etten, R.A.1    Jackson, P.2    Baltimore, D.3
  • 60
    • 0024558944 scopus 로고
    • v-src inactivate transformation and modulate membrane stability
    • v-src inactivate transformation and modulate membrane stability. J. Virol. 63:291-302.
    • (1989) J. Virol. , vol.63 , pp. 291-302
    • Wang, H.-C.1    Parsons, J.T.2
  • 61
    • 0027406462 scopus 로고
    • Abl tyrosine kinase in signal transduction and cell-cycle regulation
    • Wang, J. Y. J. 1993. Abl tyrosine kinase in signal transduction and cell-cycle regulation. Curr. Opin. Genet. Dev. 3:35-43.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 35-43
    • Wang, J.Y.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.