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Volumn 47, Issue 4, 1994, Pages 599-610

DNA-binding activity and biological effects of aromatic polyamidines

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; AROMATIC POLYAMIDE; DIMINAZENE ACETURATE; DISTAMYCIN A; PENTAMIDINE; POLYAMIDINE; PROPAMIDINE; STILBAMIDINE; UNCLASSIFIED DRUG;

EID: 0028211441     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(94)90121-X     Document Type: Article
Times cited : (42)

References (121)
  • 2
    • 0023007801 scopus 로고
    • Purification and biochemical characterization of the promoter specific transcription factor Sp1
    • (1986) Science , vol.234 , pp. 47-50
    • Briggs1    Kadonaga2    Bell3    Tjian4
  • 3
    • 0024546028 scopus 로고
    • Promoter specificity and modulation of RNA polymerase II transcription
    • (1989) FASEB J , vol.3 , pp. 1723-1733
    • Saltzman1    Weinmann2
  • 4
    • 0023739967 scopus 로고
    • A family of human CCAAT-box-binding proteins active in transcription and DNA replication: Cloning and expression of multiple cDNAs
    • (1988) Nature , vol.334 , pp. 218-224
    • Santoro1    Mermod2    Andrews3    Tjian4
  • 5
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell1    Tjian2
  • 6
    • 0025818452 scopus 로고
    • HIV-1 structural gene expression requires the binding of multiple REV monomers to the viral RRE: Implication for HIV-1 latency
    • (1991) Cell , vol.65 , pp. 241-248
    • Malim1    Cullen2
  • 9
    • 0023648332 scopus 로고
    • Molecular recognition between oligopeptides and nucleic acids. Monocationic imidazole lexitropsins that display enhanced GC sequence dependent DNA binding
    • (1987) Biochemistry , vol.26 , pp. 5590-5595
    • Kissinger1    Krowicki2    Dabrowiak3    Lown4
  • 10
    • 0022455164 scopus 로고
    • Structure-activity relationship of novel oligopeptide antiviral and antitumour agents related to netropsin and distamycin
    • (1986) J Med Chem , vol.29 , pp. 1210-1218
    • Lown1    Krowicki2    Balzarini3    De Clerq4
  • 11
    • 0023937678 scopus 로고
    • Lexitropsins: Rationale design of DNA sequence reading agents as novel anticancer agents and potential cellular probes
    • (1988) Anticancer Drug Des , vol.3 , pp. 25-35
    • Lown1
  • 12
    • 0018959948 scopus 로고
    • Existence of an extended series of antitumor compounds which bind to deoxyribonucleic acid by nonintercalative means
    • (1980) Biochemistry , vol.19 , pp. 1101-1111
    • Braithwaite1    Baguley2
  • 13
    • 0022693818 scopus 로고
    • Design of sequence-specific DNA binding molecules
    • (1986) Science , vol.232 , pp. 464-471
    • Dervan1
  • 14
    • 0023143089 scopus 로고
    • Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide
    • (1987) J Am Chem Soc , vol.109 , pp. 1574-1575
    • Wade1    Dervan2
  • 15
    • 0022006369 scopus 로고
    • The location of cis-acting regulatory sequences in human T-cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat
    • (1985) Cell , vol.41 , pp. 813-823
    • Rosen1    Sodroski2    Haseltine3
  • 18
    • 0021919896 scopus 로고
    • Pathways of viral infections. Basic concepts derived from the retrovirus model. N
    • (1985) Engl J Med , vol.312 , pp. 486-497
    • Sharpe1    Fields2
  • 25
    • 0015855925 scopus 로고
    • Hydroxystilbamidine. A nonintercalating drug as a probe of nucleic acid conformation
    • (1973) Biochemistry , vol.12 , pp. 4827-4834
    • Festy1    Daune2
  • 32
    • 0026578006 scopus 로고
    • Structure and DNA binding activity of analogs of l,5-bis(4-amidinophenoxy)pentane (pentamidine)
    • (1992) J Med Chem , vol.35 , pp. 431-438
    • Cory1    Tidwell2    Fairlay3
  • 37
    • 0024316524 scopus 로고
    • Friend erythroleukemic cells treated with aromatic poly-amidines exhibiting antiproteinase activity: Inhibition of cell growth is not associated with block of induced erythroid differentiation
    • (1989) The Cancer J , vol.2 , pp. 335-340
    • Nastruzzi1    Feriotto2    Barbieri3    Gambari4
  • 43
    • 0023109415 scopus 로고
    • Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia
    • (1987) Drugs , vol.33 , pp. 242-258
    • Goa1    Campoli-Richards2
  • 44
    • 0025989394 scopus 로고
    • Treatment and prophylaxis of Pneumocystis carinii pneumonia in AIDS patient
    • (1991) Drugs , vol.42 , pp. 628-639
    • Smith1    Gazzard2
  • 45
    • 0026691267 scopus 로고
    • Efficacy and effects on pulmonary function tests of weekly 600 mg aerosol pentamidine as prophylaxis against Pneumocystis carinii pneumonia
    • (1992) Infection , vol.20 , pp. 136-139
    • Ong1    Dunbar2    Mandal3
  • 48
    • 0025371742 scopus 로고
    • Tetra-amidines exhibiting anti-proteinase activity: Effects on oriented migration and in vitro invasiveness of a Chinese hamster cell line transfected with the activated human T24-Ha-ras-1 oncogene
    • (1990) Cancer Lett , vol.50 , pp. 93-102
    • Nastruzzi1    Barbieri2    Ferroni3    Guarneri4    Spandidos5    Gambari6
  • 51
    • 0021203313 scopus 로고
    • Malignant transformation of early passage rodent cells by a single mutated human oncogene
    • (1984) Nature , vol.310 , pp. 469-471
    • Spandidos1    Wilkie2
  • 53
    • 84909828362 scopus 로고    scopus 로고
    • Nastruzzi C and Gambari R, Antitumor activity of (trans)dermally delivered aromatic tetra-amidines. J Controlled Release, in press.
  • 55
    • 84909877369 scopus 로고    scopus 로고
    • Nastruzzi C, Pastesini C, Cortesi R, Esposito E, Gambari R and Manegatti E, Production and in vitro evaluation of gelatin microspheres containing an antitumour tetra-amidine.J Microencapsulation, in press.
  • 60
    • 0016794966 scopus 로고
    • New aromatic diamidines with central α-oxyalkane or α,ω-dioxyalkane chains. Structure-activity relationships for the inhibition of trypsin, pancreatic kallikrein, and thrombin and for the inhibition of the overall coagulation process
    • (1975) J Med Chem , vol.18 , pp. 477-481
    • Geratz1    Cheng2    Tidwell3
  • 65
    • 0014945759 scopus 로고
    • Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalation
    • (1970) J Mol Biol , vol.54 , pp. 247-279
    • Waring1
  • 67
    • 0023650355 scopus 로고
    • Hydroxy radical footprinting of the sequence-selective binding of netropsin and distamycin to DNA
    • (1987) FEES Lett , vol.225 , pp. 195-200
    • Portugal1    Waring2
  • 68
    • 0027122080 scopus 로고
    • Minor-groove width and accessibility in B-DNA drug and protein complexes
    • (1992) FEES Lett , vol.298 , pp. 97-99
    • Neidle1
  • 69
    • 0023915860 scopus 로고
    • Assignment of DNA binding sites for 4'-6-diamidine-2-henylindole and bisbenzimide (Hoechst 33258). A comparative study
    • (1988) Biochim Biophys Acta , vol.949 , pp. 158-168
    • Portugal1    Waring2
  • 72
    • 0023040893 scopus 로고
    • 1H NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer
    • (1986) Biochemistry , vol.25 , pp. 3296-3303
    • Klevit1    Wemmer2    Reid3
  • 73
    • 0023177036 scopus 로고
    • Comparison of binding sites in DNA for berenil, netropsin and distamycin: A footprinting study
    • (1987) Eur J Biochem , vol.167 , pp. 281-289
    • Portugal1    Waring2
  • 74
    • 0025179321 scopus 로고
    • Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents
    • (1990) Nucleic Acids Res , vol.18 , pp. 4479-4488
    • Laughton1    Jenkins2    Fox3    Neidle4
  • 75
    • 0025293775 scopus 로고
    • Footprinting studies on the sequence-selective binding of pentamidine to DNA
    • (1990) FEBS Lett , vol.266 , pp. 150-154
    • Fox1    Sansom2    Stevens3
  • 76
    • 0026707681 scopus 로고
    • Crystal structure of a pentamidine-oligonucleotide complex: Implication for DNA-binding properties
    • (1992) Biochemistry , vol.31 , pp. 7104-7109
    • Edwards1    Jenkins2    Neidle3
  • 78
  • 79
    • 0019863480 scopus 로고
    • A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication
    • (1981) Nucleic Acids Res , vol.9 , pp. 6231-6250
    • Tyndall1    La Mantia2    Thatcher3    Favaloro4    Kamen5
  • 81
    • 0024251459 scopus 로고
    • The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain
    • (1988) Genes Dev , vol.2 , pp. 1582-1588
    • Sturm1    Das2    Herr3
  • 82
    • 0023875830 scopus 로고
    • Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene
    • (1987) Cell , vol.51 , pp. 773-781
    • Fletcher1    Heinz2    Roeder3
  • 83
    • 0026078977 scopus 로고
    • Oncogenic conversion by regulatory changes in transcription factors
    • (1991) Cell , vol.64 , pp. 303-315
    • Lewin1
  • 84
    • 0024557039 scopus 로고
    • The “initiator” as a transcriptional control element
    • (1989) Cell , vol.57 , pp. 103-113
    • Smale1    Baltimore2
  • 85
    • 0025034666 scopus 로고
    • Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site
    • (1990) Mol Cell Biol , vol.10 , pp. 653-661
    • Means1    Farnham2
  • 86
    • 0026447291 scopus 로고
    • Transcription by RNA polymerase II: Initiator-directed formation of transcription-competent complexes
    • (1992) FASEB J , vol.6 , pp. 3300-3309
    • Weis1    Reinberg2
  • 87
    • 0025351398 scopus 로고
    • Mechanism of transcriptional activation by Spl: Evidence for coactivators
    • (1989) Cell , vol.61 , pp. 1187-1197
    • Pugh1    Tjian2
  • 89
    • 0024525146 scopus 로고
    • Gel electrophoresis assays for DNA-protein interactions
    • (1989) Biotechniques , vol.7 , pp. 346-355
    • Revzin1
  • 90
    • 0005576326 scopus 로고
    • Gel electrophoresis of protein-DNA complexes
    • (1987) Nature , vol.325 , pp. 464-465
    • Crothers1
  • 94
    • 0019878376 scopus 로고
    • Equilibria and kinetics of lac represser-operator interactions by polyacrylamide gel electrophoresis
    • (1981) Nucleic Acids Res , vol.9 , pp. 6505-6525
    • Fried1    Crothers2
  • 95
    • 0023955176 scopus 로고
    • Gel retardation at low pH resolves trp repressor-DNA complexes for quantitative study
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 975-979
    • Carey1
  • 97
    • 0020435972 scopus 로고
    • Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
    • (1982) Mol Cell Biol , vol.2 , pp. 1044-1051
    • German1    Moffat2    Howard3
  • 98
    • 0026593492 scopus 로고
    • A simple quantitative assay for chloramphenicol acetyltransferase by direct extraction of the labeled product into scintillation cocktail
    • (1992) Anal Biochem , vol.200 , pp. 180-186
    • Sankaran1
  • 99
    • 0024357103 scopus 로고
    • In vitro transcription analysis of the role of DNA flanking sequences on adriamycin sequence selectivity
    • (1989) Nucleic Acids Res , vol.17 , pp. 3673-3679
    • Trist1    Phillips2
  • 108
    • 0025281145 scopus 로고
    • The mouse albumin enhancer contains a negative regulatory element that interacts with a novel DNA-binding protein
    • (1990) Mot Cell Biol , vol.10 , pp. 3896-3905
    • Herbst1    Boczko2    Darnell3    Babiss4
  • 109
    • 0024791938 scopus 로고
    • Molecular cloning and characterization of a human DNA binding factor that represses transcription
    • (1989) Cell , vol.59 , pp. 815-825
    • Kageyama1    Pastan2
  • 112
    • 0026029808 scopus 로고
    • Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
    • (1991) Cell , vol.64 , pp. 573-584
    • Boyle1    Smeal2    Defize3    Angel4    Woodget5    Karin6    Hunter7
  • 114
    • 0025767317 scopus 로고
    • Transcription inhibition of the somatic-type phosphoglycerate kinase 1 gene in vitro by a testis-specific factor that recognizes a sequence similar to the binding site for Ets oncoproteins
    • (1991) Nucleic Acids Res , vol.19 , pp. 3959-3963
    • Goto1    Tamura2    Mikoshiba3    Masamune4    Nakanishi5
  • 116
    • 0023790222 scopus 로고
    • Nef protein of HIV-1 is a transcriptional represser of HIV-1 LTR
    • (1988) Science , vol.241 , pp. 1481-1485
    • Ahmad1    Venkatesan2


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