Small Molecule Binding to an Artificially Created Cavity at the Active Site of Cytochrome c Peroxidase

Biochemistry

Volumn 33, Issue 13, 1994, Pages 3807-3818

  Fitzgerald, Melissa M ^a   Churchill, Michael J ^a   McRee, Duncan E ^a   Goodin, David B ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLIMIDAZOLE; 2 ETHYLIMIDAZOLE; 2 METHYLIMIDAZOLE; BENZIMIDAZOLE; CYTOCHROME C PEROXIDASE; DIMETHYLIMIDAZOLE; IMIDAZOLE; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STABILITY; ESCHERICHIA COLI; HYDROGEN BOND; MUTANT; NONHUMAN; PH; PRIORITY JOURNAL; STEREOSPECIFICITY; THERMOSTABILITY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME-C PEROXIDASE; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028209418     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00179a004     Document Type: Article

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