Gangliosides in the protection against glutamate excitotoxicity

Progress in Brain Research

Volumn 101, Issue C, 1994, Pages 357-373

  Costa, E ^a   Armstrong, D M ^a   Guidotti, A ^a   Kharlamov, A ^a   Kiedrowski, L ^a   Manev, H ^b   Polo, A ^a   Wroblewski, J T ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FIDIA S P A   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIZOCILPINE; GANGLIOSIDE; GANGLIOSIDE GM1; GLUTAMATE RECEPTOR; LIGA 20; LIGA 4; RECEPTOR SUBTYPE; SPHINGOSINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN REGION; CALCIUM TRANSPORT; CONFERENCE PAPER; INTRAVENOUS DRUG ADMINISTRATION; NEUROTOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMAL; EVOKED POTENTIALS; GANGLIOSIDES; HUMAN; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0028209302     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/S0079-6123(08)61962-7     Document Type: Article

References (46)

1. Baumann, N., Harpin, M.L., Jacque, C., Brain ganglio-sides in shiverer mouse: Comparison with other dysmyelinated mutants, quaking and jumpy. Baumann, N., (eds.) Neurological Mutations Affecting Myelination, 1980, Elsevier North Holland, Amsterdam, 257–262 INSERM Symposium 14.
2. Candeo, P., Favaron, M., Lengyel, I., Manev, R.M., Rimland, J.M., Manev, H., Pathological phosphorylation causes neu-ronal death: Effect of okadaic acid in primary culture of cerebel-lar granule cells. J. Neurochem 59 (1992), 1558–1561.
3. Chen, L., Huang, L.Y.M., Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanisms of modulation. Nature 356 (1992), 521–523.
4. Choi, D.W., Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7 (1988), 369–379.
5. Choi, D.W., Excitatory amino acid neurotransmitters: Anatomical systems. Meldrum, B.S., (eds.) Excitatory Amino Acid Antagonists, 1991, Blackwell Scientific Publications, Oxford, 14–38.
6. Seren, M.C., Comelli, M.S., Guidolin, D., Manev, R.M., Favaron, M., Rimland, J.M., Canella, R., Negro, A., Manev, H., Photochemical stroke and brain derived neurotropic factor mRNA expression. Neuroreport 3 (1992), 437–476.
7. Conn, P.J., Desai, M.A., Pharmacology and physiology of metabotropic glutamate receptors in mammalian central nervous system. Drug Dev. Res. 24 (1991), 207–229.
8. Connor, J.A., Wadman, W.J., Hockberger, P.E., Sustained dendritic gradients of Ca2+ induced by excitatory amino acid in CAI hippocampal neurons. Science 240 (1988), 649–653.
9. Costa, E., Kharlamov, A., Guidotti, A., Hayes, R., Armstrong, D., Sequelae of biochemical events following photochemical injury of rat sensory-motor cortex: Mechanism of ganglio-side protection. Physiopathol. Exp. Ther. 14 (1992), 17–23.
10. De Erausquin, G., Manev, H., Guidotti, A., Costa, E., Brooker, G., Gangliosides normalize distorted single cell intracel-lular free Ca2+ dynamics after toxic doses of glutamate in cere-bellar granule cells. Proc. Natl. Acad. Sci. USA 87 (1990), 8017–8021.
11. Dietrich, W.D., Watson, B.D., Busto, R., Ginsberg, M.D., Bethea, J.R., Photochemically induced cerebral infartion I early microvascular alternations. Acta Neurol 72 (1987), 315–334.
12. Facci, L., Leon, A., Skaper, S.D., Hypoglycemic neurotoxicity in vitro: Involvement of excitatory amino acid receptors and attenuation by monosialoganglioside GMI. Neuroscience. 37 (1990), 709–716.
13. Favaron, M., Manev, H., Alho, H., Bertolino, M., Ferret, B., Guidotti, A., Costa, E., Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc. Natl. Acad. Sci., USA 85 (1988), 7351–7355.
14. Favaron, M., Manev, H., Siman, R., Bertolino, M., Szekely, A.M., de Erausquin, G., Guidotti, A., Costa, E., Down regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate induced neuronal death. Proc. Natl. Acad. Sci., USA 87 (1990), 1983–1987.
15. Fernandez, M.T., Zitko, V., Gascon, S., Novelli, A., The murine Toxin Okadeic acid is a potent neurotoxin for cultured cerebellar neurons. Life Sci. 49 (1991), 157–162.
16. Ghidoni, R., Riboni, L., Tettamanti, G., Metabolisms of exogenous gangliosides in cerebellar granular cells differentiated in culture. J. Neurochem. 53 (1989), 1567–1574.
17. Higashi, H., Omozi, A., Yamagoto, T., Calmodulin, a ganglioside binding protein. J. Biol. Chem. 267 (1992), 9831–9838.
18. Hollman, M., O'Shea-Greenfield, A., Rogers, W., Heineman, S., Ca2+ permeability of KA-AMPA-gated glutamate receptor channels depend on subunit composition. Science 252 (1991), 851–853.
19. A. Kharlamov A. Guidotti E. Costa R. Hayes D. Armstrong (1993) Semisynthetic sphingolipids prevent protein kinase C translocation and neuronal damage in the proyocal area following a photochemically-induced thrombotic brain cortical lesion. J. Neuroscience.
20. Kiedrowski, L., Manev, H., Costa, E., Wroblewski, J.T., Inhibition of glutamate induced neuronal death by sodium nitro-prusside is not mediated by nitric oxide. Neuropharmacology 30 (1991), 1241–1243.
21. Manev, H., Favaron, M., Guidotti, A., Costa, E., Delayed increase of Ca2+ influx elicited by glutamate: Role in neuronal death. Mol. Pharmacol. 36 (1989), 106–112.
22. Manev, H., Favaron, M., Vicini, S., Guidotti, A., Ganglioside mediated protection from glutamate induced neuronal death. Acta Neurobiol. Exp. 50 (1990), 475–488.
23. Manev, H., Costa, E., Wroblewski, J.T., Gudiotti, A., Abusive stimulation of excitatory amino acid receptors: A strategy to limit neurotoxicity. FASEB J. 4 (1990), 2789–2797.
24. Manev, H., Favaron, M., Vicini, S., Guidotti, A., Costa, E., Glutamate induced neuronal death in primary cultures of cerebellar granule cells: Protection by synthetic derivatives of endogenous sphingolipids. J. Pharmacol. Exp. Ther. 252 (1990), 419–427.
25. Manev, H., Favaron, M., Siman, R., Guidotti, A., Costa, E., Glutamate neruotoxicity is independent of calpain 1 inhibition in primary cultures of cerebellar granule cells. J. Neurochem. 57 (1991), 1288–1295.
26. Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., Nakanishi, S., Sequence and expression of a metabotropic glutamate receptor. Nature 349 (1991), 760–765.
27. Mattson, M.P., Evidence of the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons. Exp. Neurol. 111 (1991), 95–103.
28. Meldrum, B.S., Smith, S.E., Le Peillet, E., Moncada, C., Arvin, B., Antagonists acting at non-NMDA receptors as cere-broprotective agents in global and focal ischemia. Simon, R.P., (eds.) Excitatory Amino Acids, 9, 1992, Thieme Medical Publishers, New York, 235–239.
29. Nicoletti, F., Ladarola, M.J., Wroblewski, J.T., Costa, E., Excitatory amino acid recognition sites coupled and with inosi-tal phospholipid metabolism: Developmental changes and interaction with α1 adreneceptors. Proc. Natl. Acad. Sci. USA 83 (1986), 1931–1935.
30. Nicoletti, F., Wroblewksi, J.T., Novelli, A., Alho, H., Guidotti, A., Costa, E., The activation of isonitol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. J. Neurosci. 6 (1986), 1905–1911.
31. Novelli, A., Nicoletti, F., Wroblewski, J.T., Alho, H., Costa, E., Guidotti, A., Excitatory amino acid receptors coupled with granulate cyclase in primary cultures of cerebellar granule cells. J. Neurosci. 7 (1987), 547–554.
32. Olney, J.W., Labruyere, J., Price, M.T., Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244 (1989), 1360–1362.
33. Purpura, D., Ectopic dendritic growth in mature pyromidal neurons in human ganglioside storage disease. Nature 276 (1978), 520–521.
34. Qi, Y., Xue, Q.M., Ganglioside levels in hypoic brains from neonatal and premature infants. Mol. Chem. Neuropathol. 16 (1991), 87–95.
35. Sakmann, B., Elementary steps in synaptic transmission revealed by currents through single ion channels. Neurons 8 (1992), 613–629.
36. Sladeczek, F., Recasens, M., Bockaert, J., A new mechanism for glutamate reception action: Phosphoinositide hydrolysis. Trends Neurosci. 11 (1988), 545–549.
37. Sommer, B., Seeburg, P.H., Glutamate receptor channels: novel properties and new clones. TIPS 13 (1992), 291–296.
38. Sommer, B., Keinanen, K., Verdon, T.A., Wisden, W., Burnashev, N., Herb, A., Kohler, M., Tagaki, T., Sakmann, B., Seeburg, P.H., Flip and Flop: A cell specific functional switch in glutamate-operated channels of CNS. Science 249 (1990), 1580–1585.
39. Sommer, B., Kohler, M., Sprengle, R., Seeburg, P.H., RNA editing in brain controls a determinant of ion flow in gluta-mate gated channel. Cell 67 (1991), 11–20.
40. Sonnino, S., Cantu, L., Corti, M., Acquotti, D., Kirschner, G., Tettamanti, G., Aggregation properties of semisynthetic GM1 ganglioside (113 Neu 5-Ac Gg Ose4 Cer) containing an acetyl group as acylmoiety. Chem. Phys. Lipids 56 (1990), 49–57.
41. Szekely, A.M., Costa, E., Grayson, D.R., Transcriptional program coordination by NMDA-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons. Mol. Pharmacol. 38 (1990), 624–633.
42. Tanabe, Y., Masu, M., Ishis, T., Shigemoto, R., Nakanishi, S., A family of metabotropic glutamate receptors. Neuron 8 (1992), 169–179.
43. Vaccarino, F., Guidotti, A., Costa, E., Ganglioside inhibition of glutamate mediated protein kinase C translocation in primary cultures of cerebellar neurons. Proc Natl. Acad. Sci. USA 84 (1988), 8707–8710.
44. Watson, D.B., Dietrich, W.D., Busto, R., Wachtel, M.S., Ginstery, M.D., Induction of reproducible brain infarction by pho-tochemically initiated thrombosis. Am. Neurol. 17 (1985), 497–504.
45. Wroblewksi, J.T., Raulli, R., Lazarewicz, J.W., Kiedrowski, L., Costa, E., Wroblewska, B., Intracellular messengers generated by glutamate receptors in primary cultures of cerebellar neurons. Barnard, E.A., (eds.) Transmitter Amino Acid Receptors: Structures, Transduction and Models of Drug Development, 6, 1991, Thieme Medical Publishers, New York, 379–393.
46. Zukin, R.S., Pellegrini-Giampietro, D.E., McGurk, J.F., Bennett, M.V.L., Molecular biological studies of glutamate receptors in the developing brain. Simon, R.P., (eds.) Excitatory Amino Acids, 9, 1992, Thieme Medical Publishers, New York, 47–51.