Erythropoietin stimulates testosterone production in man

Journal of Clinical Endocrinology and Metabolism

Volumn 78, Issue 3, 1994, Pages 753-756

  Foresta, C ^a,b   Mioni, R ^a   Bordon, P ^a   Miotto, D ^a   Montini, G ^a   Varotto, A ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; GONADORELIN; LUTEINIZING HORMONE; RECOMBINANT ERYTHROPOIETIN; TESTOSTERONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FOLLITROPIN BLOOD LEVEL; GONADOTROPIN RELEASE; HUMAN; LEYDIG CELL; LUTEINIZING HORMONE BLOOD LEVEL; MALE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SPERMATIC VEIN; STEROIDOGENESIS; TESTOSTERONE RELEASE; TESTOSTERONE SYNTHESIS; VARICOCELE;

ADOLESCENT; ADULT; ERYTHROPOIETIN; GONADOTROPIN-RELEASING HORMONE; GONADOTROPINS, PITUITARY; HUMANS; MALE; RECOMBINANT PROTEINS; TESTIS; TESTOSTERONE; VEINS;

EID: 0028209035     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.78.3.753     Document Type: Article

References (23)

1. Ishibashi T, Koziol JA, Burstein SA. 1987 Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro. J Clin Invest. 79:286-293.
2. Krantz SB. 1990 Erythropoietin. Blood. 77:419-434.
3. Graber SE, Krantz SB. 1978 Erythropoietin and the control of red blood cell production. Annu Rev Med. 29:51-66.
4. D'Andrea AD, Zon LI. 1990 Erythropoietin receptor. J Clin Invest. 86:681-687.
5. Winearls CG, Oliver DO, Pippard MJ, Reid C, Downing MR, Cotes PM. 1986 Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintined by chronic haemodialysis. Lancet. 2:1175-1178.
6. Eschbach JW, Egrie JC, Downing MR, Browne JK, Adamson JW. 1987 Correction of the anaemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med. 316:73-78.
7. Schaefer RM, Kokot F, Heidland A. 1988 Normalization of prolactin levels and improved sexual function in dialysis patients on erythopoietin. Nephrol Dial Transplant. 3:501-508.
8. Kokot F, Wiecek A, Grzeszczak W, Klepacka J, Klin M, Lao M. 1989 Influence of erythropoietin treatment on endocrine abnormalities in haemodialyzed patients. In: Baldamus CA, Scigalla P, Wieczorek L, Koch KM, eds. Erythropoietin: from molecular structure to clinical application. Contributions to nephology. Basel: Karger; vol 76:257-272.
9. Schaefer RM, Kokot F, Wernze H, Geiger H, Heidland A. 1989 Improved sexual function in haemodialysis patients on recombinan erythropoietin: a possible role for prolactin. Clin Nephrol. 31:1-5.
10. Nissenson AR. 1989 Recombinant human erythropoietin: impact on brain and cognitive function, exercise tollerance, sexual potency, and quality of life. Semin Nephrol. 9:25-31.
11. Mioni R, Gottardello F, Bordon P, Montini G, Foresta C. 1992 Evidence for specific binding and stimulatory effects of recombinant human erythropoietin on isolated adult rat Leydig cells. Acta Endocrinol (Copenh). 127:459-465.
12. Foresta C, Mioni R, Miotto D, De Carlo E, Facchin F, Varotto A. 1991 Stimulatory effects of alpha-hANP on testosterone secretion in man. J Clin Endocrinol Metab. 72:392-395.
13. Bellvè A, Zheng W. 1989 Growth factors as autocrine and paracrine modulators of male gonadal function J Reprod Fertil. 85:771-793.
14. Foresta C, Caretto A, Varotto A, Rossato M, Scandellari C. 1991 Epidermal growth factor receptors (EGFr) localization in human testis. Arch Androl. 27:17-21.
15. Dalla Rosa C, Cascone C, Antonucci F, Mastrogiacomo I, Foresta C. 1977 Hypothalamic-hypophyseal-gonadal axis in patients undergoing chronic hemodialysis. Kidney Int. 12:80-81.
16. Steward-Bentley M, Gans D, Horton R. 1974 Regulation of gonadal function in uremia. Metabolism. 23:1065-1072.
17. Nagel TC, Freinkel N, Bell RH, Freisen H, Wilber JF, Metzger BE. 1973 Gynecomastia, prolactin, and other peptide hormones in patients undergoing chronic hemodialysis J Clin Endocrinol Metab. 36:428-432.
18. Olgaard K, Hagen C, McNeilly AS. 1975 Pituitary hormones in women with chronic renal failure: the effect of chronic intermittent hemo- and peritoneal dialysis. Acta Endocrinol (Copenh). 80:237-246.
19. Ramirez G, Bittle PA, Sanders H, Bercu BB. 1992 Hypothalamo-hypophyseal thyroid and gonadal function before and after erythropoietin therapy in dialysis patients. J Clin Endocrinol Metab. 74:517-24.
20. Bancroft J, Wu FCW. 1983 Changes in erectile responsiveness during androgen replacement therapy. Arch Sex Behav. 12:59-66.
21. Zanjani ED, Ascensao JL. 1989 Erythropoietin. Transfusion. 29:46-57.
22. Thomsen K, Riis B, Krabbe S, Christiansen C. 1986 Testosterone regulates the hemoglobin concentration in male puberty. Acta Paediatric Scand. 75:793-796.
23. Claustres M, Sultan C. 1986 Stimulatory effects of androgens on normal children's bone marrow in culture: effects on BFU-e, CFU-e and uroporphyrinogen I syntase activity. Horm Res. 23:91-98.