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84952482945
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Prepared in thre steps from 3-methyl-2,4-pentanedione: 1. imidazole, hexamethyldisilazane; 2. methyllithium; 3. p-toluenesulfonic acid, ethanol.
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Prepared in thre steps from 3-methyl-2,4-pentanedione: 1. imidazole, hexamethyldisilazane; 2. methyllithium; 3. p-toluenesulfonic acid, ethanol.
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21
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see reference 9 in this paper.
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For a review of allylic 1,3-strain effects in synthesis, see
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84952482946
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Ketoester 31 was prepared from 3-acetoxy-2-butanone in three steps: 1. sodium trimethylphosphonoacetate; 2. potassium carbonate in methanol; 3. Swern oxidation.
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Ketoester 31 was prepared from 3-acetoxy-2-butanone in three steps: 1. sodium trimethylphosphonoacetate; 2. potassium carbonate in methanol; 3. Swern oxidation.
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