Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 91, Issue 6, 1994, Pages 2344-2348

  Wu, Jianguo ^a   Zhou, Tong ^a   Zhang, Jinju ^a   He, Jin ^a   Gause, William C ^b   Mountz, John D ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

autoimmunity; systemic lupus erythematosus

Indexed keywords

COMPLEMENTARY DNA; DNA ANTIBODY; DOUBLE STRANDED DNA; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL SELECTION; FEMALE; GENE MUTATION; HISTOLOGY; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA ANALYSIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; TRANSGENIC MOUSE; UREA NITROGEN BLOOD LEVEL;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0028206729     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.91.6.2344     Document Type: Article

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