Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 91, Issue 10, 1994, Pages 4155-4159

  Rothstein, Jeffrey D ^a   Bristol, Lynn A ^b   Hosler, Betsy ^c   Brown Jr , Robert H ^c   Kuncl, Ralph W ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

amyotrophic lateral sclerosis; antioxidant; free radicals; motor neuron; organotypic culture

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; 3 HYDROXYASPARTIC ACID; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ANTISENSE OLIGODEOXYNUCLEOTIDE; CHLORAMPHENICOL ACETYLTRANSFERASE; DIETHYLDITHIOCARBAMIC ACID; DITHIOTHREITOL; PHOSPHOROTHIOIC ACID; SUPEROXIDE DISMUTASE; THIOGLYCOLIC ACID;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME INHIBITION; MOTONEURON; NERVE CELL; NERVE CELL DEGENERATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL NERVE;

ANIMALIA;

EID: 0028205372     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.91.10.4155     Document Type: Article

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