Local production of cytokines in the human cardiac allograft: A sequential study

Transplantation

Volumn 57, Issue 9, 1994, Pages 1333-1337

  Cunningham, D A ^a   Dunn, M J ^a   Yacoub, M H ^a   Rose, M L ^a  

^a HAREFIELD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; LYMPHOTOXIN; METHYLPREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; DISEASE SEVERITY; GENE EXPRESSION; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE SUBPOPULATION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RNA ANALYSIS;

BASE SEQUENCE; BIOLOGICAL MARKERS; CYTOKINES; DNA PRIMERS; ELECTROPHORESIS, AGAR GEL; GENE EXPRESSION; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMAN; MOLECULAR SEQUENCE DATA; MYOCARDIUM; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSPLANTATION, HOMOLOGOUS;

EID: 0028204311     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199405150-00008     Document Type: Article

References (29)

1. Cernetti C, Steinman RM, Granelli-Piperno A. Identification of a 24 kDa cytokine that is required for development of cytolytic lymphocytes. Proc Natl Acad Sci USA 1988; 85: 1605.
2. Stephens HP, van der Kwast TH, van der Meide PH, Vuzevski VD, Buurmen WA, Jonker M. Synergistic immunosuppressive effects of monoclonal antibodies specific for interferon-gamma and tumor necrosis factor alpha. A skin transplantation study in the rhesus monkey. Transplantation 1990; 50: 856.
3. Thornhill H, Wellicome SM, Mahiouz DL, Lanchbury JSS, Kyan- Aung V, Haskard D. Tumor necrosis factor combines with IL4 or IFN to selectively enhance endothelial cell adhesiveness for T cells. J Immunol 1988; 141: 499.
4. Sato N, Goto T, Haranako K, et al. Actions of tumor necrosis factor on cultured vascular endothelial cells: morphologic modulation, growth inhibition and cytotoxicity. J Natl Cancer Inst 1986; 76: 1113.
5. Mossman TR, Coffman RL. Thl and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7: 145.
6. de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL10) and viral IL10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991; 174: 915.
7. Takeuchi T, Lowry RP, Koniezny B. Heart allografts in murine systems: the differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
8. Billingham ME, Cary NR, Hammond ME, et al. A working for mulation for the standardization of heart and lung rejection: heart rejection study group. J Heart Transplant 1990; 9: 587.
9. Chomycznski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156.
10. Krug MS, Berger SL. First-strand cDNA synthesis primed with oligo(dT). In: Berger SL, Kimmel AR, eds. Guide to molecular cloning techniques. Methods Enzymol 1987; 152: 316.
11. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: A labo ratory manual (2nd ed). Cold Spring Harbor, NY: ('old Spring Harbor Laboratory Press, 1989.
12. March CJ, Mosley B, Larsen A, et al. Cloning, sequence and expression of two distinct human interleukin cDNAs. Nature 1985; 315: 641.
13. Taniguchi T, Matsui H, Fujita T, et al. Structure and expression of a cloned cDNA for human interleukin 2. Nature 1983; 302: 305.
14. Yokata T, Otsuka T, Mosmann T, et al. Isolation and character ization of a human cDNA clone homologous to mouse B-cell stimulatory factor 1, that expresses B cell and T cell stimulating activities. Proc Natl Acad Sci USA 1986; 83: 5894.
15. Pennica D, Nedwin G, Hayflick JS, et al. Human tumour necro sis factor: precursor structure, expression and homology to lymphotoxin. Nature 1984; 312: 724.
16. Gray PW, Aggarval BB, Benton CV, et al. Cloning and expres sion of cDNA for lymphotoxin, a lymphokine with tumour necrosis activity. Nature 1984; 312: 721.
17. Weiss LM, Movahad LA, Billingham M, Cleary ML. Detection of Coxsackievirus B3 RNA in myocardial tissues by the polymerase chain reaction. Am J Pathol 1991; 138: 497.
18. Vieira P, de Waal-Malefy R, Dang MN, et al. Isolation and ex pression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc Natl Acad Sci USA 1991; 88: 1172.
19. Dallman MJ, Larsen CP, Morris PJ. Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction. J Exp Med 1991; 174: 493.
20. Wu CJ, Lovett M, Wong-Lee J, et al. Cytokine gene expression in rejecting cardiac allografts. Transplantation 1992; 54: 326.
21. Papp I, Wieder KJ, Sablinski T, et al. Evidence for functional heterogeneity of rat CD4+ T cells in vivo: differential expression of IL2 and IL4 mRNA in recipients of cardiac allografts. J Immunol 1992; 148: 1308.
22. Dallman MJ, Roake J, Hughes D, Toogood G, Morris PJ. Sequen tial analysis of IL2 gene transcription in renal transplants. Transplantation 1992; 53: 683.
23. Kirk AD, Ibrihim MA, Bollinger RR, Dawson DV, Finn OJ. Renal allograft infiltrating lymphocytes: a prospective analysis of in- vitro growth characteristics and clinical relevance. Transplantation 1992; 53: 329.
24. Merville P, Pouteil-Noble C, Wijdenes J, Potaux L, Touraine JL, Banchereau J. Detection of single cells secreting IFN-gamma, IL6 and IL10 in irreversibly rejected human kidney allografts and their modulation by IL2 and IL4. Transplantation 1993; 55: 639.
25. Martinez OM, Krams S, Sterneck M, et al. Intragraft cytokine profile during human liver allograft rejection. Transplantation 1992; 53: 449.
26. Nathan C, Sporn M. Cytokines in context. J Cell Biol 1991; 113: 981.
27. Arbustini E, Grasso M, Diegoli M, et al. Expression of TNFα in human acute cardiac rejection: an immunohistochemical and immunoblotting study. Am J Pathol 1991; 139: 709.
28. Jordan S, Czer L, Toyoda M, et al. Serum cytokine levels in heart allograft recipients: correlation with findings on endomyocardial biopsy. J Heart Lung Transplant 1993; 12: 333.
29. Fyfe A, Daly P, Galligan L, Pirc L, Feindel C, Cardella C. Coro nary sinus sampling of cytokines after heart transplantation: evidence for macrophage activation and IL4 production within the graft. JACC 1993; 21: 171.