Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: The cobalt(III)-nitrogen mustard complex SN 24771

International Journal of Radiation Oncology, Biology, Physics

Volumn 29, Issue 2, 1994, Pages 323-327

  Wilson, William R ^a   Moselen, John W ^a   Cliffe, Stephen ^a   Denny, William A ^b   Ware, David C ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b Cancer Research Laboratory University of Auckland School of Medicine ^*

Author keywords

Cobalt(III) complex; Diffusible cytotoxins; EMT6 spheroids; K curve; Nitrogen mustard; SN 24771

Indexed keywords

AROMATIC NITRO COMPOUND; CHLORMETHINE; COBALT COMPLEX; DIAZIQUONE; MISONIDAZOLE; MITOMYCIN C; N,N DI(2 CHLOROETHYL)ETHYLENEDIAMINE; PORFIROMYCIN; QUINONE DERIVATIVE; SN 24771; UNCLASSIFIED DRUG;

CELL KILLING; CELL LINE; CELL SURVIVAL; CELL SUSPENSION; CLONOGENIC ASSAY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; HYPOXIC CELL; MULTICELLULAR SPHEROID; OXYGEN CONCENTRATION; PRIORITY JOURNAL; RADIOSENSITIZATION;

ANOXIA; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; CELLS, CULTURED; DIFFUSION; MECHLORETHAMINE; NITROGEN MUSTARD COMPOUNDS; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; OXYGEN; SUPPORT, NON-U.S. GOV'T;

EID: 0028200679     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(94)90283-6     Document Type: Article

References (9)

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