Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons - A possible novel pathogenetic mechanism in Parkinson's disease

Neuroscience Letters

Volumn 170, Issue 1, 1994, Pages 136-140

  Ziv, Ilan ^a   Melamed, Eldad ^a   Nardi, Nurit ^a   Luria, Drorit ^a   Achiron, Anat ^a   Offen, Daniel ^a   Barzilai, Ari ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Apoptosis; DNA damage; Dopamine; Flow cytometry; Free radical; Parkinson's disease

Indexed keywords

DOPAMINE; FREE RADICAL;

ADRENERGIC SYSTEM; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; NERVE CELL; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

ANIMAL; APOPTOSIS; CELL NUCLEUS; CELLS, CULTURED; CHICK EMBRYO; DNA DAMAGE; DOPAMINE; DYES; FLOW CYTOMETRY; NEURONS; PARKINSON DISEASE; SUPPORT, NON-U.S. GOV'T; SYMPATHETIC NERVOUS SYSTEM; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0028198186     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(94)90258-5     Document Type: Article

References (21)

1. Death gives birth to the nervous system
2. Mechanisms of cell death
3. Cell death by apoptosis and its protective role against disease
4. Apoptosis
5. Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry
6. Activation of programmed cell death by anticancer agents: cisplatin as a model system
7. Cooperative interaction between c-myc and bcl-2 proto-oncogenes
8. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
9. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward c1300 neuroblastoma cells in vitro
10. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed-cell death
11. Quantitation of fluorescence of biogenic monoamines
12. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
13. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by NGF deprivation
14. Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture
15. Genetic toxicity of dopamine
16. A rapid and simple method for measuring thymocyte apoptosis by propidium-iodide staining and flow cytometry
17. A radical hypothesis for neurodegeneration
18. Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease
19. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
20. Dopamine: a novel antitumor agent active against B-16 melanoma in vivo
21. Levodopa/Dopamine Analogs as Inhibitors of DNA Synthesis in Human Melanoma Cells.