Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs

International Journal of Pharmaceutics

Volumn 106, Issue 1, 1994, Pages 15-23

  Shah, N H ^a   Carvajal, M T ^a   Patel, C I ^a   Infeld, M H ^a   Malick, A W ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

Nonionic surfactant; Polyglycolyzed glyceride; Self emulsification

Indexed keywords

APRICOT KERNEL OIL; ARACHIS OIL; CAPMUL MCM90; CORN OIL; DECANOIC ACID; EMULSIFYING AGENT; FATTY ACID; LABRAFAC CM 10; LABRAFAC CM 6; LABRAFAC CM 8; LABRAFAC HYDRO; LABRAFIL M 1944 CSD; LABRAFIL M 2125 CS; LABRAFIL NA 10; LABRASOL; LINOLEIC ACID; MACROGOL; NAPHTHALENE DERIVATIVE; NEOBEE M5; OCTANOIC ACID; OLEIC ACID; PEGLICOL 5 OLEATE; POLYETHYLENEGLYCOL 25 GLYCERYL TRIOLEATE; POLYSORBATE 80; TEMAROTENE; UNCLASSIFIED DRUG;

ARTICLE; DISSOLUTION; DOG; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; LIPOPHILICITY; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PARTITION COEFFICIENT; PRIORITY JOURNAL;

EID: 0028194817     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(94)90271-2     Document Type: Article

References (8)

1. Oral delivery of lipophilic drugs in selfemulsifying liquid formulations
2. Self-emulsifying drug delivery systems: assessment of the efficiency of emulsification
3. Factors affecting the in vitro efficiency of self-emulsifying delivery systems