Changing Enzymic Reaction Mechanisms by Mutagenesis: Conversion of a Retaining Glucosidase to an Inverting Enzyme

Journal of the American Chemical Society

Volumn 116, Issue 25, 1994, Pages 11594-11595

  Wang, Qingping ^a   Withers, S G ^a   Graham, R W ^b   Trimbur, D ^b   Warren, R A J ^b  

^a Chemistry Department   (Canada)

^b Departments of Microbiology and Immunology   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0028191018     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja00104a060     Document Type: Article

References (26)

1. Koshland, D.E. Biol. Rev. 1953, 28, 416.
2. Sinnott, M.L. Chem. Rev. 1990, 90, 1171.
3. Legler, G. Adv. Carbohydr Chem. Biochem. 1990, 48, 319.
4. Sinnott, M.L. In Enzyme Mechanisms; Page, M.I., Williams, A., Eds.; Royal Society of Chemistry: London, 1987; p 259.
5. Burk, D.; Wang, Y.; Dombroski, D.; Berhuis, A.M.; Evans, S.V.; Luo, Y.; Withers, S.G.; Brayer, G.D. J. Mol. Biol. 1993, 230, 1084.
6. Swift, H.J.; Brady, R.L.; Derewenda, Z.S.; Dodson, E.J.; Turemburg, J.P.; Wilkinson, A. J. Acta Crystallogr. 1991, B47, 535.
7. Brady, R.L.; Brzozowski, A.M.; Derewenda, Z.S.; Dodson, E.J.; Dodson, G.G. Acta Crystallogr. 1991, B47, 527.
8. Larson, S.B.; Greenwood, A.; Cascio, D.; Day, J.; McPherson, A. J. Mol. Biol. 1994, 235, 1560.
9. White, A.; Withers, S.G.; Gilkes, N.R.; Rose, D.R. Biochemistry 1994, 33, 12546.
10. Campell, R.; Rose, D.; Wakarchuck, W.; To, R.; Sung, W.; Yagachi, M. In Proceedings of the second TRICEL symposium on Trichoderma reesei cellulose and other hydrolase; Suominen, P., Reinikainen, T.; Eds.; Helsinski Foundation for Biotechnical and Industrial Fermentation Research: Espoo, Finland, 1993; pp 63-72.
11. Imoto, T.; Johnson, L.N.; North, A.C.T.; Phillips, D.C.; Rupley, J.A. In The Enzymes; Boyer, P.D.; Ed.; Academic Press: New York, 1972; pp 666-668.
12. Aleshin, A.; Golubev, A.; Firsov, L.M.; Honzatko, R.B. J. Biol. Chem. 1993, 267, 19291.
13. Mikami, B.; Degano, M.; Hehre, E.J.; Sacchettini, J.C. Biochemistry 1994, 33, 7779.
14. Spezio, M.; Wilson, D.B.; Karplus, P.A. Biochemistry 1993, 32, 9906.
15. Withers, S.G.; Warren, R.A.J.; Street, I.P.; Rupitz, K.; Kempton, J.B.; Aebersold, R. J. Am. Chem. Soc. 1990, 112, 5887.
16. Withers, S.G.; Rupitz, K.; Trimbur, D.; Warren, R.A. J. Biochemistry, 1992, 31, 9979.
17. Ritchie, C.D. Acc. Chem. Res. 1972, 5, 348.
18. Takeda, T.; Sugiura, Y.; Hamada, C.; Fujii, R.; Suzuki, K.; Ogihara, Y.; Shibata, S. Chem. Pharm. Bull 1981, 29, 3196.
19. Hehre, E.J.; Brewer, C.F.; Genghof, D.S. J. Biol. Chem. 1979, 254, 5942.
20. Kitahata, S.; Brewer, C.F.; Genghof, D.S.; Sawai, T.; Hehre, E.J. J. Biol. Chem. 1981, 256, 6017.
21. Hehre, E.J.; Sawai, T.; Brewer, C.F.; Nakano, M.; Kanda, T. Biochemistry 1982, 21, 3090.
22. Kasumi, T.; Brewer, C.F.; Reese, E.T.; Hehre, E.J. Carbohydr. Res. 1986, 146, 39.
23. Kasumi, T.; Tsumuraya, Y.; Brewer, C.F.; Kersters-Hilderson, H.; Claeyssens, M.; Hehre, E.J. Biochemistry 1987, 26, 3010.
24. Hehre, E.J.; Matsui, H.; Brewer, C.F. Carbohydr. Res. 1990, 198, 123.
25. Kuroki, R.; Weaver, L.H.; Matthews, B.W. Science 1993, 262, 2030.
26. Guo, X.; Laver, W.G.; Vimr, E.; Sinnott, M.L. J. Am. Chem. Soc. 1994, 116, 5572.