The pharmacokinetics of p-boronophenylalanine.fructose in human patients with glioma and metastatic melanoma

International Journal of Radiation Oncology, Biology, Physics

Volumn 28, Issue 5, 1994, Pages 1183-1188

  Mallesch, Julia L ^a,b   Moore, Douglas E ^a   Allen, Barry J ^b   McCarthy, William H ^c   Jones, Robert ^d   Stening, Warwick A ^e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d PRINCE OF WALES HOSPITAL   (Australia)

^e PRINCE HENRY HOSPITAL   (Australia)

Author keywords

BNCT; Glioma; Melanoma; p Boronophenylalanine; Pharmacokinetics

Indexed keywords

4 BORONOPHENYLALANINE; FRUCTOSE;

AREA UNDER THE CURVE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; GLIOMA; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MELANOMA; METASTASIS; NEUTRON CAPTURE THERAPY; PHARMACOKINETICS; PRIORITY JOURNAL;

BORON; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; GLIOMA; HUMAN; MELANOMA; PHENYLALANINE; RADIATION-SENSITIZING AGENTS; SUPPORT, NON-U.S. GOV'T;

EID: 0028181078     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(94)90493-6     Document Type: Article

References (7)

1. Local control of SC melanoma xenografts in nude mice by neutron capture therapy
2. Affinity of the melanin precursor analog p- Boron ophenylalanine for tumors other than melanoma
3. A phase one biodistribution study of p-Boronophenylalanine
4. A rat model for the treatment of melanoma metastatic to the brain by means of neutron capture therapy
5. Advances in the control of human cutaneous primary and metastatic melanoma by thermal neutron capture therapy
6. Determination of boron in biological tissues by inductively coupled plasma atomic emission spectrometry
7. Improvement of solubility of p-Boronophenylalanine by complex formation with monosaccharides