17p Allelic Losses in Diploid Cells of Patients with Barrett's Esophagus Who Develop Aneuploidy

Cancer Research

Volumn 54, Issue 9, 1994, Pages 2292-2295

  Blount, Patricia L ^a   Galipeau, Patricia C ^a   Sanchez, Carissa A ^a   Neshat, Katayoun ^a   Levine, Douglas S ^a   Yin, Jing ^a   Suzuki, Hiroyuki ^a   Abraham, John M ^a   Meitzer, Stephen J ^b   Reid, Brian J ^c  

^a University of Maryland ^*

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ALLELE; ANEUPLOIDY; ARTICLE; BARRETT ESOPHAGUS; CHROMOSOME 17P; CLINICAL ARTICLE; DIPLOIDY; GENE ACTIVATION; GENE LOSS; GENETIC STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL;

ADENOCARCINOMA; ALLELES; ANEUPLOIDY; BARRETT ESOPHAGUS; BASE SEQUENCE; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 17; DNA MUTATIONAL ANALYSIS; ESOPHAGEAL NEOPLASMS; GENES, P53; HUMAN; KI-67 ANTIGEN; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; SEQUENCE ANALYSIS, DNA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028180125     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Nowell, P.C. The clonal evolution of tumor cell populations. Science (Washington DC), 194: 23-28, 1976.
2. Vogelstein, B. Fearon, E.R. Hamilton, S.R. Kern, S.E. Preisinger, A.C. Leppert, M. Nakamura, Y. White, R. Mits, A.M. and Bos, T.L. Genetic alterations during colorectal tumorigenesis. N. Engl. J. Med. 319: 525-532, 1988.
3. Sidransky, D. Mikkelson, T. Schwechheimer, K. Cavanee, W. Rosenblum, M.L. and Vogelstein, B. Clonal expansion of p. 3 mutant cells is associated with brain tumor progression. Nature (Lond.), 355: 846-847, 1992.
4. Blount, P.L. Meltzer, S.J. Yin, J. Huang, Y. Krasna, M.J. and Reid, B.J. Clonal ordering of 17p and 5q allelic losses in Barrett dysplasia and adenocarcinoma. Proc. Natl. Acad. Sci. USA, 90: 3221-3225, 1993.
5. Kastan, M.B. Onyekwere, O. Sidransky, D. Vogelstein, B. and Craig, R.W. Participation of p. 3 protein in the cellular response to DNA damage. Cancer Res. 51: 6304-6311, 1991.
6. Kastan, M.B. Zhan, Q. el Deiry, W.S. Carrier, F. Jacks, T. Walsh, W.V. Plunkett, B.S. Vogelstein, B. and Fornance, A.J. Jr. A mammalian cell cycle checkpoint pathway utilizing p. 3 and GADD45 is defective in ataxia-telangiectasia. Cell, 71: 587-597, 1992.
7. Livingstone, L.R. White, A. Sprouse, J. Livanos, E. Jacks, T. and Tlsty, T.D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p. 3. Cell, 70: 923-936, 1992.
8. Yin, Y. Tainsky, M.A. Bischoff, F.Z. Strong, L. and Wahl, G.M. Wild-type p. 3 restores cell cycle control and inhibits gene amplification in cells with mutant p. 3 allele. Ceil, 70: 937-948, 1992.
9. Reid, B.J. Barrett's esophagus and esophageal adenocarcinoma. Gastroenterol. Clin. North. Am. 20: 817-834, 1991.
10. Rabinovitch, P.S. Reid, B.J. Haggitt, R.C. Norwood, T.H. and Rubin, C.E. Progression to cancer in Barrett's esophagus is associated with genomic instability. Lab. Invest. 60: 65-71, 1988.
11. Reid, B.J. Blount, P.L. Rubin, C.E. Levine, D.S. Haggitt, R.C. and Rabinovitch, P.S. Flow cytometric and histological progression to malignancy in Barrett's esophagus: prospective endoscopic surveillance of a cohort. Gastroenterology, 102: 1212-1219, 1992.
12. Blount, P.L. Ramel, S. Raskind, W.H. Haggitt, R.C. Sanchez, C.A. Dean, P.J. Rabinovitch, P.S. and Reid, B.J. 17p allelic deletions and p. 3 protein overexpression in Barrett's adenocarcinoma. Cancer Res. 51: 5482-5486, 1991.
13. Neshat, K. Sanchez, C.A. Galipeau, P.C. Blount, P.L. Levine, D.S. Joslyn, G. and Reid, B.J. p. 3 mutations in Barrett's adenocarcinoma and high-grade dysplasia. Gastroenterology, in press, 1994.
14. Casson, A.G. Mukhopadhyay, T. Cleary, K.R. Ro, J.Y. Levin, B. and Roth, J.A. p. 3 gene mutations in Barrett's epithelium and esophageal cancer. Cancer Res. 51: 4495-4499, 1991.
15. Huang, Y. Meltzer, S.J. Yin, J. Tong, Y. Chang, E.G. Srivastava, S. McDaniel, T. Boynton, R.F. and Zou, S.Q. Altered mRNA and unique mutational profiles of p. 3 and Rb in human esophageal carcinomas. Cancer Res. 53: 1889-1894, 1993.
16. Greenwald, B.D. Huang, Y. Baum, R. and Meltzer, S.J. Barrett's carcinoma in a 25-year-old man with point mutation of the p. 3 tumor suppressor gene. Int. J. Oncol. 1: 271-275, 1992.
17. Huang, Y. Boynton, R.F. Blount, P.L. Silverstein, R.J. Yin, J. Tong, Y. McDaniel, T.K. Newkirk, C. Resau, J.H. Sridhara, R. Reid, B.J. and Meltzer, S.J. Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancers. Cancer Res. 52: 6525-6530, 1992.
18. Reid, B.J. Sanchez, C.A. Blount, P.L. and Levine, D.S. Barrett's esophagus: cell cycle abnormalities in advancing stages of neoplastic progression. Gastroenterology, 105: 119-129, 1993.
19. Gerdes, J. Lemke, H. Baisch, H. Wacker, H.H. Schwab, U. and Stein, H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki67. J. Immunol. 133: 1710-1715, 1984.
20. Hereford, L.M. and Hartwell, L.H. Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis. J. Mol. Biol. 84: 445-461, 1974.
21. Offerhaus, A. Johan, G. DeFeyter, E.P. Cornelisse, C.J. Tersmette, K.W. Floyd, J. Kern, S.E. Vogelstein, B. and Hamilton, S.R. The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma. Gastroenterology, 102: 1612-1619, 1992.
22. Blount, P.L. Rabinovitch, P.S. Haggitt, R.C. and Reid, B.J. Early Barrett's adenocarcinoma arises within a single aneuploid population. Gastroenterology, 98: 273a, 1990.