Prostaglandin E2 inhibits T cell-dependent Ig secretion by neonatal but not adult lymphocytes

Journal of Immunology

Volumn 152, Issue 11, 1994, Pages 5259-5267

  Splawski, Judy B ^a   Lipsky, Peter E ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BUCLADESINE; CD5 ANTIGEN; CYCLIC AMP; DIMETHYL SULFOXIDE; FORSKOLIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; ISOBUTYLMETHYLXANTHINE; PROSTAGLANDIN E2; RECOMBINANT INTERLEUKIN 2; CYTOKINE; IMMUNOGLOBULIN; LEUKOCYTE ANTIGEN;

ADULT; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTE FUNCTION; NEWBORN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; UMBILICAL CORD BLOOD; B LYMPHOCYTE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; FETUS BLOOD; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; T LYMPHOCYTE;

ADULT; ANTIGENS, CD; ANTIGENS, CD5; B-LYMPHOCYTES; CELLS, CULTURED; CYCLIC AMP; CYTOKINES; DINOPROSTONE; FETAL BLOOD; HUMAN; IMMUNOGLOBULINS; INFANT, NEWBORN; LYMPHOCYTE ACTIVATION; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0028179895     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Stenson, W. F., and C. W. Parker. 1982. Prostaglandins and the immune response. In Prostaglandins. J. B. Lee, ed. Elsevier North Holland, New York, p. 39.
2. 2. J. Immunol. 133: 2446.
3. 2: suppression of the generation of immunoglobulin secreting cells. J. Clin. Invest. 75: 1339.
4. 2. J. Immunol. 138: 1074.
5. Jelinek, D. F., J. B. Splawski, and P. E. Lipsky. 1986. Human peripheral blood B lymphocyte subpopulations: functional and phenotypic analysis of surface IgD positive and negative subsets. J. Immunol. 136:83.
6. Splawski, J., and P. Lipsky. 1991. Cytokine regulation of immunoglobulin secretion by neonatal lymphocytes. J. Clin. Invest. 88:967.
7. Hansen, J., P. Martin, P. Beatty, E. Clark, and J. Ledbetter. 1984. Human T lymphocyte cell surface molecules defined by the workshop monoclonal antibodies (T cell protocol). In Leukocyte Typing. A. Bernard, L. Boumsell, J. Dausset, C. Milstein, and S. F. Schlossman eds. Springer-Verlag, New York, p. 195.
8. Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood: isolation of mononuclear cells by one centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Invest. 21(Suppl. 97):77.
9. Splawski, J. B., and P. E. Lipsky. 1991. Isolation of B cell populations. In Current Protocols in Immunology. J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober eds. Greene Publishing and Wiley-Interscience, New York, 7.5.1.
10. Thiele, D., M. Kurosaka, and P. Lipsky. 1983. Phenotype of the accessory cells necessary for mitogen stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotrophic agent, L-leucine methyl ester. J. Immunol. 131: 2282.
11. Thiele, E., and P. Lipsky. 1985. Modulation of human natural killer cell function by L-leucine methyl ester: monocyte-dependent depletion from human peripheral blood mononuclear cells. J. Immunol. 134:786.
12. Galili, U., and M. Sclesinger. 1974. The formation of stable E rosettes after neuraminidase treatment of either peripheral blood lymphocytes or of sheep red blood cells. J. Immunol. 112:1628.
13. Jelinek, D., and P. Lipsky. 1985. The role of T cell factors in activation, cell cycle progression, and differentiation of human B cells. J. Immunol. 134:1690.
14. Wysocki, L., and V. Sato. 1978. Panning for lymphocytes: a method for cell selection. Proc. Natl. Acad. Sci. USA 75:2844.
15. Geppert, T., and P. Lipsky. 1987. Accessory cell-independent proliferation of human T4 cells stimulated by immobilized monoclonal antibodies to CD3. J. Immunol. 138:1660.
16. Nicoletti, I., G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139:271.
17. Splawski, J., D. Jelinek, and P. Lipsky. 1989. Immunomodulatory role of IL-4 on the secretion of Ig by human B cells. J. Immunol. 142:1569.
18. Robinson, D. R., and L. Levine. 1974. Prostaglandin concentrations in synovial fluid in rheumatic diseases: action of indomethacin and aspirin. In Prostaglandin Synthetase Inhibitors. H. J. Robinson and J. R. Vane, eds. Raven Press, New York, p. 223.
19. 2 in maternal and neonatal lymphocytes. Am. J. Rep. Immunol. Microbiol. 9:105.
20. + suppressor cells. J. Immunol. 139:688.
21. - B cell subsets to T cell-independent mitogens. Eur. J. Immunol. 21: 351.
22. Gadol, N., and K. Ault. 1986. Phenotypic and functional characterization of human Leu 1 (CD5) B cells. Immunol. Rev. 93:23.
23. Papadogiannakis, N., S.-A. Johnsen, S. Rosberg, R. G. Anderson, and L. B. Olding. 1989. Differential sensitivity to cAMP among human cord and maternal/adult peripheral lymphocytes discloses differences between PHA- and OKT3-induced activation pathways. Immunology 68:378.
24. Rappaport, R., and G. Dodge. 1982. Prostaglandin E inhibits the production of human interleukin 2. J. Exp. Med. 155:943.
25. Goodwin, J., A. Bankhurst, and R. Messner. 1977. Suppression of human T cell mitogenesis by prostaglandin. J. Exp. Med. 146:1719.
26. 2-induced inhibition of interleukin 2 production. J. Immunol. 130:1770.
27. Shad, V. C., and R. P. Phipps. 1988. Two signals are required for accessory cells to induce B cell unresponsiveness: tolerogenic Ig and Prostaglandin. J. Immunol. 141:79.
28. Phipps, R. P., R. L. Roper, and S. H. Stein. 1990. Regulation of B-Cell tolerance and triggering by macrophages and lymphoid dendritic cells. Immunol. Rev. 117:135.
29. 2 and cAMP inhibit B lymphocyte activation and simultaneously promote IgE and IgG1 synthesis. J. Immunol. 149:2984.
30. Pollok, K. E., V. O'Brien, L. Marshall, J. W. Olson, R. J. Noelle, and E. C. Snow. 1991. The development of competence in resting B cells: the induction of cyclic AMP and ornithine decarboxylase activity after direct contact between B and T helper cells. J. Immunol. 146:1633.
31. Tohma, S., S. Hirohata, and P. E. Lipsky. 1991. The role of CD11a/ CD18-CD54 interactions in human T cell-dependent B cell activation. J. Immunol. 146:492.
32. Armitage, R. J., W. C. Fanslow, L. Strockbine, T. A. Sato, K. N. Clifford, B. M. Macduff, D. M. Anderson, S. D. Gimpel, T. Davis-Smith, C. R. Maliszewski, E. A. Clark, C. A. Smith, K. H. Grabstein, D. Cosman, and M. K. Spriggs. 1992. Molecular and biological characterization of a murine ligand for CD40. Nature 357:80.
33. Armitage, R. J., B. M. Macduff, M. K. Spriggs, and W. C. Fanslow. 1993. Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. J. Immunol. 150:3671.
34. Splawski, J., and P. Lipsky. 1991. Delineation of the functional capacity of human neonatal lymphocytes. J. Clin. Invest. 87:545.
35. McConkey, D. J., S. Orrenius, and M. Jondal. 1990. Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J. Immunol. 145:1227.
36. 2 induces apoptosis in immature normal and malignant B lymphocytes. Clin. Immunol. Immunopathol. 63:221.
37. 2. J. Immunol. 145:2616.
38. Sanders, M., M. Makgoba, S. Sharrow, D. Stephany, T. Springer, H. Young, and S. Shaw. 1988. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-γ production. J. Immunol. 140:1401.
39. Ehlers, S., and K. Smith. 1991. Differentiation of T cell lymphokine gene expression: The in vitro acquisition of T cell memory. J. Exp. Med. 173:25.
40. 2 on B cell activation by two distinct B cell differentiation factors, B151-TRF1/IL-5 and B151-TRF2: selective inhibition of B151-TRF2-induced antibody response through increases in intracellular cyclic AMP levels, Immunology 68:154.
41. 2-induced changes in the phenotype, morphology, and lytic activity of IL-2-activated natural killer cells. J. Immunol. 150:3747.