Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells

Journal of Immunology

Volumn 152, Issue 11, 1994, Pages 5208-5219

  Larsen, Christian P ^a,d   Ritchie, Shannon C ^a   Hendrix, Rose ^a   Linsley, Peter S ^b   Hathcock, Karen S ^c   Hodes, Richard J ^c   Lowry, Robin P ^a   Pearson, Thomas C ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d EMORY UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CD28 ANTIGEN; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; MONOCLONAL ANTIBODY; RECOMBINANT GAMMA INTERFERON; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELLULAR IMMUNITY; DENDRITIC CELL; EPIDERMIS CELL; FLOW CYTOMETRY; IMMUNOSTIMULATION; KIDNEY CELL; LANGERHANS CELL; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD80; ANTIGENS, CD86; ANTIGENS, DIFFERENTIATION; BASE SEQUENCE; CELL LINE; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNOCONJUGATES; INTERFERON TYPE II; LANGERHANS CELLS; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA;

EID: 0028179886     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Steinman, R. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9:271.
2. Schuler, G., and R. M. Steinman. 1985. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J. Exp. Med. 161:526.
3. Inaba, K., G. Schuler, M. D. Witmer, J. Valinsky, B. Atassi, and R. Steinman. 1986. Immunologic properties of purified epidermal Langerhans cells: distinct requirements for stimulation of unprimed and sensitized T lymphocytes. J. Exp. Med. 164:605.
4. Witmer-Pack, M., W. Oliver, J. Valinsky, G. Schuler, and R. M. Steinman. 1987. Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells. J. Exp. Med. 166:1484.
5. Heufler, C., F. Koch, and G. Schuler. 1987. Granulocyte-macro-phage colony-stimulating factor and interleukin-1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells. J. Exp. Med. 167:700.
6. Romani, N., S. Koide, M. Crowley, M. Witmer-Pack, A. M. Livingstone, C. G. Fathman, K. Inaba, and R. M. Steinman. 1989. Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best by immature, epidermal Langerhans cells. J. Exp. Med. 169:1169.
7. Kupiec-Weglinski, J. W., J. M. Austyn, and P. J. Morris. 1988. Migration patterns of dendritic cells in the mouse: traffic from blood, and T cell- dependent and independent entry to lymphoid tissues. J. Exp. Med. 167:632.
8. Macatonia, S. E., S. C. Knight, A. J. Edwards, S. Griffiths, and P. Fryer. 1987. Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. J. Exp. Med. 166:1654.
9. Larsen, C. P., H. Barker, P. J. Morris, and J. M. Austyn. 1990. Mature dendritic cells of the host fail to migrate from the blood into cardiac or skin allografts. Transplantation 50:294.
10. Codner, M. A., B. A. Shuster, R. M. Steinman, A. D. Harper, G. S. LaTrenat, and L. A. Huffman. 1991. Migration of donor leukocytes from limb allografts into host lymphoid tissues. Ann. Plastic Surg. 25:353.
11. Austyn, J. M., J. W. Kupiec-Weglinski, D. F. Hankins, and P. J. Morris. 1988. Migration patterns of dendritic cells in the mouse: homing to T cell-dependent areas of spleen, and binding with marginal zone. J. Exp. Med. 167:646.
12. Larsen, C. P., P. J. Morris, and J. M. Austyn. 1990. Migration of dendritic leukocytes from cardiac allografts into host spleens: a novel route for initiation of rejection. J. Exp. Med. 171:307.
13. Larsen, C. P., R. M. Steinman, M. Witmer-Pack, D. F. Hankins, P. J. Morris, and J. M. Austyn. 1990. Migration and maturation of Langerhans cells in skin transplants and explants. J. Exp. Med. 172:1483.
14. Liu, Y., and P. S. Linsley. 1992. Costimulation of T-cell growth. Curr. Opin. Immunol. 4:265.
15. Boussiotis, V. A., G. J. Freeman, G. Gray, J. Gribben, and L. M. Nadler. 1993. B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J. Exp. Med. 178:1753.
16. Lindsten, T., K. P. Lee, E. S. Harris, B. Petryniak, N. Craighead, P. J. Reynolds, D. B. Lombard, G. J. Freeman, L. M. Nadler, G. S. Gray, C. B. Thompson, and C. H. June. 1993. Characterization of CTLA-4 structure and expression on human T cells. J. Immunol. 151:3489.
17. Wu, Y., Y. Guo, and Y. Liu. 1993. A major costimulatory molecule on antigen-presenting cells, CTLA4 ligand A, is distinct from B7. J. Exp. Med. 178:1789.
18. Hathcock, K. S., G. Laszlo, H. B. Dickler, J. Bradshaw, P. Linsley, and R. J. Hodes. 1993. Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262:905.
19. Freeman, G. J., F. Borriello, R. J. Hodes, H. Reiser, K. S. Hathcock, G. Laszlo, A. J. McKnight, J. Kim, L. Du, D. B. Lombard, G. S. Gray, L. M. Lombard, and A. H. Sharpe. 1993. Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262:907.
20. Freeman, G. J., J. G. Gribben, V. A. Boussiotis, J. W. Ng, V. A. Restivo, L. A. Lombard, G. S. Gray, and L. M. Nadler. 1993. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262:909.
21. Azuma, M., D. Ito, H. Yagita, K. Okumura, J. Phillips, L. Lanier, and C. Somoza. 1993. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366:76.
22. Freeman, G., F. Borriello, R. Hodes, H. Reiser, J. G. Gribben, J. W. Ng, J. Kim, J. M. Goldberg, K. Hathcock, G. Laszlo, L. A. Lombard, S. Wang, G. S. Gray, L. M. Nadler, and A. H. Sharpe. 1993. Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production. J. Exp. Med. 178: 2185.
23. Liu, Y., W. Jones, C. Brady, C. Janeway, and P. Linsley. 1992. Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat stable antigen. Eur. J. Immunol. 22:2855.
24. + T lymphocytes by human blood dendritic cells in vitro. J. Clin. Invest. 90:229.
25. Larsen, C. P., S. C. Ritchie, T. C. Pearson, P. S. Linsley, and R. P. Lowry. 1992. Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations. J. Exp. Med. 176: 1215.
26. Metlay, J. P., M. D. Witmer-Pack, R. Agger, M. T. Crowley, D. Lawless, and R. M. Steinman. 1990. The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies. J. Exp. Med. 171:1753.
27. Linsley, P. S., W. Brady, M. Urnes, L. Grosmaire, N. Damle, and J. A. Ledbetter. 1991. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 174:561.
28. Juhlin, L., and W. Shelly. 1977. New staining technique for the Langerhans cell. Acta Derm. Verneol. 57:289.
29. Montgomery, R. A., and M. J. Dallman. 1991. Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J. Immunol. 147:554.
30. Liu, Y., B. Jones, A. Aruffo, K. M. Sullivan, P. S. Linsley, and C. A. J. Janeway. 1992. Heat-stable antigen is a costimulatory molecule for CD4 T cell growth. J. Exp. Med. 175:437.
31. Inaba, K., R. M. Steinman, M. W. Pack, H. Aya, M. Inaba, T. Sudo, S. Wolpe, and G. Schuler. 1992. Identification of proliferating dendritic cell precursors in mouse blood. J. Exp. Med. 175:1157.
32. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
33. Koide, S. L., K. Inaba, and R. Steinman. 1987. Interleukin-1 enhances T-dependent immune responses by amplifying the function of dendritic cells. J. Exp. Med. 165:515.
34. Dustin, M. L., and T. A. Springer. 1991. Role of lymphocyte adhesion receptors in transient interaction and cell locomotion. Annu. Rev. Immunol. 9:27.
35. Freedman, A. S., G. J. Freeman, K. Rhynhart, and L. M. Nadler. 1991. Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell. Immunol. 137:429.
36. Holt, P. G., M. A. Schon-Hegrad, and J. Oliver. 1988. MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat: regulation of antigen presentation by endogenous macrophage populations. J. Exp. Med. 167:262.
37. Austyn, J., D. Hankins, C. Larsen, P. Morris, A. Rao, and J. Roake. Isolation and characterization of dendritic cells from mouse heart and kidney. J. Immunol. In press.
38. Inaba, K., and R. M. Steinman. 1984. Resting and sensitized T lymphocytes exhibit distinct stimulatory requirements for growth and lymphokine release. J. Exp. Med. 160:1711.
39. Austyn, J. M., and C. P. Larsen. 1990. Migration patterns of dendritic leukocytes: implications for transplantation. Transplantation 48:1.
40. Linsley, P. S., J. L. Greene, P. Tan, J. Bradshaw, J. A. Ledbetter, C. Anasetti, and N. K. Damle. 1992. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes. J. Exp. Med. 176:1595.
41. Pure, E., K. Inaba, M. T. Crowley, L. Tardelli, M. D. Witmer-Pack, G. Ruberti, G. Fathman, and R. M. Steinman. 1990. Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain. J. Exp. Med. 172:1459.