p53 gene mutations in oropharyngeal carcinomas: A comparison of solitary and multiple primary tumours and lymph‐node metastases

International Journal of Cancer

Volumn 56, Issue 6, 1994, Pages 807-811

  Zariwala, Maimoona ^a   Schmid, Stephan ^a   Pfaltz, Madeleine ^a   Ohgaki, Hiroko ^a   Kleihues, Paul ^a   Schäfer, Reinhold ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; MULTIPLE CANCER; OROPHARYNX CARCINOMA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; AGED; BASE SEQUENCE; CODON; COMPARATIVE STUDY; FEMALE; GENES, P53; HUMAN; LYMPHATIC METASTASIS; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; NEOPLASMS, MULTIPLE PRIMARY; OROPHARYNGEAL NEOPLASMS; POINT MUTATION; SEQUENCE ANALYSIS, DNA; SUPPORT, NON-U.S. GOV'T;

EID: 0028174225     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.2910560608     Document Type: Article

References (28)

1. Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer
2. Polymorphism at codon 213 within the p53 gene
3. Detection of mutations in the p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis
4. Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)‐7β,8α‐dihydroxy‐9α,10α‐epoxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene
5. Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract
6. Second malignancies in patients who have head and neck cancer: incidence, effect on survival and implications based on the RTOG experience
7. Molecular basis of base substitution hotspots in Escherichia coli
8. Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens
9. Risk factors for second cancers of the upper respiratory and digestive systems: a case‐control study
10. The importance of p53 gene alterations in human cancer: is there more than circumstantial evidence?
11. Consumption of tobacco as an etiologic factor in a group of 465 oral cancer patients in Israel
12. p53 mutations in human cancers
13. Role of human papillomavirus in human cancer
14. Formation of DNA modifications by chemical carcinogens, identification, localization and quantification
15. The clonal evolution of tumor cell populations
16. p53 increases experimental metastatic capacity of murine carcinoma cells
17. The p53 tumor‐suppressor gene and ras oncogene mutations in oral squamous‐cell carcinoma
18. Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor‐suppressor genes
19. Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small‐cell lung carcinoma
20. The etìology and prevention of aerodigestive tract cancers
21. “Field cancerization” in oral stratified squamous epithelium
22. Frequent p53 mutations in head and neck cancer
23. A deadly inheritance