Multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca2+-induced enhancement of the L-type Ca2+ current in rabbit ventricular myocytes

Circulation Research

Volumn 75, Issue 5, 1994, Pages 854-861

  Anderson, Mark E ^a   Braun, Andrew P ^b   Schulman, Howard ^b   Premack, Brett A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ current; Ca2+ calmodulin kinase; Cardiac myocytes; Fluo 3; Nitr 5

Indexed keywords

ANILINE DERIVATIVE; CA(2+) CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CHELATING AGENT; DRUG DERIVATIVE; EGTAZIC ACID; FLUO 3; FLUO-3; FLUORESCENT DYE; NITR 5; PROTEIN KINASE (CALCIUM,CALMODULIN); XANTHENE DERIVATIVE; CALMODULIN BINDING PROTEIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID;

ANIMAL; ARTICLE; CALCIUM CHANNEL; CELL SURVIVAL; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; FLUORESCENCE; HEART VENTRICLE; IN VITRO STUDY; METABOLISM; PHOTOLYSIS; PHYSIOLOGY; RABBIT; ANIMAL CELL; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ANILINE COMPOUNDS; ANIMAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNELS; CELL SURVIVAL; CHELATING AGENTS; COMPARATIVE STUDY; EGTAZIC ACID; FLUORESCENCE; FLUORESCENT DYES; HEART VENTRICLE; IN VITRO; PHOTOLYSIS; RABBITS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; XANTHENES;

EID: 0028171306     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.75.5.854     Document Type: Article

References (50)

1. Stern MD, Lakatta EG. Excitation-contraction coupling in the heart: the state of the question. FASEB J. 1992;6:3092-3100.
2. Pelzer D, Pelzer S, McDonald TF. Properties and regulation of calcium channels in muscle cells. Rev Physiol Biochem Pharmacol. 1990;114:108-207.
3. Hartzell HC. Regulation of cardiac ion channels by catecholamines, acetylcholine and second messenger systems. Prog Biophys Mol Biol. 1988;52:165-247.
4. 2+ channels. Nature. 1988;335:249-251.
5. Dosemeci A, Dhallan RS, Cohen NM, Lederer WJ, Rogers TB. Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circ Res. 1988;62:347-357.
6. Shearman MS, Sekiguchi K, Nishizuka Y. Modulation of ion channel activity: a key function of the protein kinase C enzyme family. Pharmacol Rev. 1989;41:211-237.
7. Lee KS, Marban E, Tsien RW. Inactivation of calcium channels in mammalian heart cells: joint dependence on membrane potential and intracellular calcium. J Physiol (Lond). 1985;364:395-411.
8. 2+ in dorsal root ganglion neurons. Science. 1988;241:842-844.
9. Eckert R, Chad JE. Inactivation of calcium channels. Prog Biophys Mol Biol. 1984;44:215-267.
10. 2+-activated phosphatase in mammalian brain. Trends Neurosci. 1989; 12:117-122.
11. Marban E, Tsien RW. Enhancement of calcium current during digitalis inotropy in mammalian heart: positive feed-back regulation by intracellular calcium? J Physiol (Lond). 1982;329:589-614.
12. Fedida D, Noble D, Spindler AJ. Use-dependent reduction and facilitation of Ca current in guinea pig myocytes. J Physiol (Lond). 1988;405:439-460.
13. Lee KS. Potentiation of the calcium-channel currents in internally perfused mammalian heart cells by repetitive depolarization. Proc Natl Acad Sci USA. 1987;84:3941-3945.
14. Hryshko LV, Bers DM. Ca current facilitation during postrest recovery depends on Ca entry. Am J Physiol. 1990;259:H951-H961.
15. 2+ molecules. Nature. 1989;341:65-68.
16. Manalan AS, Klee CB. Calmodulin. Adv Cyclic Nucleotide Protein Phosphoryl Res. 1984;18:227-278.
17. 2+/calmodulin-dependent protein kinases. Annu Rev Biochem. 1992;61:559-601.
18. 2+/calmodulin-dependent protein kinase isoforms. Biochim Biophys Acta. 1994;1221:89-101.
19. Malinow R, Schulman H, Tsien RW. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science. 1989;245:862-866.
20. Wagner JA, Cozens AL, Schulman H, Gruenert DC, Stryer L, Gardner P. Activation of chloride channels in normal and cystic fibrosis airway epithelial cells by multifunctional calcium/ calmodulin-dependent protein kinase. Nature. 1991;349:793-796.
21. 2+-calmodulin kinase II in cholinergic modulation of neuronal responsiveness. J Neurophysiol. 1992;68: 2264-2269.
22. McGlade-McCulloh E, Yamamoto H, Tan S-E, Brickey DA, Soderling TR. Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II. Nature. 1993; 362:640-642.
23. Witcher DR, Kovacs RJ, Schulman H, Cefali DC, Jones LR. Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J Biol Chem. 1991;266:11144-11152.
24. Wang J, Best PM. Inactivation of the sarcoplasmic reticulum calcium channel by protein kinase. Nature. 1992;359:739-741.
25. Zygmunt AC, Maylie J. Stimulation-dependent facilitation of the high threshold calcium current in guinea-pig ventricular myocytes. J Physiol (Lond). 1990;428:653-671.
26. McCarron JG, McGeown JG, Reardon S, Ikebe M, Fay FS, Walsh Jr JV. Calcium-dependent enhancement of calcium current in smooth muscle by calmodulin-dependent protein kinase II. Nature. 1992;357:74-77.
27. + current in rabbit ventricular myocytes. J Physiol (Lond). 1991;441:673-684.
28. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391: 85-100.
29. House C, Kemp BE. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science. 1987;238:1726-1728.
30. Smith MK, Colbran RJ, Soderling TR. Specificities of autoinhibitory domain peptides for four protein kinases. J Biol Chem. 1990;265:1837-1840.
31. Payne ME, Fong Y-L, Ono T, Colbran RJ, Kemp BE, Soderling TR, Means AR. Calcium/calmodulin-dependent protein kinase II: characterization of distinct calmodulin binding and inhibitory domains. J Biol Chem. 1988;263:7190-7195.
32. Nichols RA, Sihra TS, Czernik AJ, Nairn AC, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature. 1990;343:647-651.
33. Kaplan JH. Photochemical manipulation of divalent cation levels. Annu Rev Physiol. 1990;52:897-914.
34. Gurney AM, Tsien RY, Lester HA. Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons. Proc Natl Acad Sci U S A. 1987;84:3496-3500.
35. Beuckelmann DJ, Wier WG. Mechanism of release of calcium from sarcoplasmic reticulum of guinea-pig cardiac cells. J Physiol (Lond). 1988;405:233-255.
36. 2+ indicators. Biophys J. 1993;65:1632-1647.
37. Hescheler J, Nawrath H, Tang M, Trautwein W. Adrenoceptor-mediated changes of excitation and contraction in ventricular heart muscle from guinea-pigs and rabbits. J Physiol (Lond). 1988;397: 657-670.
38. 2+/calmodulin-dependent protein kinase type II by a bifunctional calmodulin-binding peptide. Proc Natl Acad Sci U S A. 1988;85:4991-4995.
39. 2+-transport ATPase and brain phosphodiesterase by activators and inhibitors. Biochem J. 1982;207:541-548.
40. Klockner U, Isenberg G. Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes. Am J Physiol. 1987;253:H1601-H1611.
41. 2+ channels in smooth muscle from rat vas deferens. Br J Pharmacol. 1993;109:137-141.
42. 2+ and voltage inactivate calcium channels in guinea-pig ventricular myocytes through independent mechanisms. J Physiol (Lond). 1991;444:257-268.
43. Armstrong D, Erxleben C, Kalman D, Lai Y, Nairn A, Greengard P. Intracellular calcium controls the activity of dihydropyridine-sensitive calcium channels through protein phosphorylation and its removal. J Gen Physiol. 1988;92:10a. Abstract.
44. 2+-dependent block and potentiation of L-type calcium current guinea-pig ventricular myocytes. J Physiol (Lond). 1993;466:345-365.
45. Jahn H, Nastainczyk W, Rohrkasten A, Schneider T, Hofmann F. Site-specific phosphorylation of the purified receptor for calcium-channel blockers by cAMP- and cGMP-dependent protein kinases, protein kinase C, calmodulin-dependent protein kinase II and casein kinase II. Eur J Biochem. 1988;178:535-542.
46. Hosey MM, Chang FC, O'Callahan CM, Ptasienski J. L-type calcium channels in cardiac and skeletal muscle. Ann N Y Acad Sci. 1990;560:27-38.
47. Yang J, Tsien RW. Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons. Neuron. 1993;10:127-136.
48. Kort AA, Lakatta EG. Spontaneous sarcoplasmic reticulum calcium release in rat and rabbit cardiac muscle: relation to transient and rested twitch tension. Circ Res. 1988;63:969-979.
49. Clusin WT. Role of calcium-activated ion currents in the heart. In: Sperelakis N, ed. Physiology and Pathophysiology of the Heart. Norwell, Mass; Kluwer Academic Publishers; 1989:95-114.
50. January CT, Fozzard HA. Delayed afterdepolarizations in heart muscle: mechanisms and relevance. Pharmacol Rev. 1988;40: 219-227.