Expression of the WT1 Wilms' tumor gene by normal and malignant human melanocytes

International Journal of Cancer

Volumn 59, Issue 1, 1994, Pages 78-82

  Rodeck, Ulrich ^a   Bossler, Anna ^a   Kari, Csaba ^a   Humphreys, Christopher W ^a   Györfi, Tibor ^a   Maurer, Jürgen ^b   Thiel, Eckhard ^b   Menssen, Hans D ^b  

^a WISTAR INSTITUTE   (United States)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; PROTEIN P53;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA CELL; NEPHROBLASTOMA; ONCOGENE; PRIORITY JOURNAL;

BASE SEQUENCE; BLOTTING, NORTHERN; DNA, COMPLEMENTARY; GENE EXPRESSION; GENES, P53; GENES, WILMS TUMOR; HUMAN; MELANOCYTES; MELANOMA; MOLECULAR SEQUENCE DATA; MUTATION; PLATELET-DERIVED GROWTH FACTOR; POLYMERASE CHAIN REACTION; RNA SPLICING; RNA, MESSENGER; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED;

EID: 0028170515     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.2910590116     Document Type: Article

References (38)

1. Induction of growth factor mRNA expression in human malignant melanoma: markers of transformation
2. cDNA sequence and chromosomal localization of human platelet‐derived growth factor A‐chain and its expression in tumor cell lines
3. Inactivation of the remaining allele of the WT1 gene in a Wilms' tumor from a WAGR patient
4. Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors
5. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
6. Maximizing sensitivity and specificity of PCR by pre‐amplification heating
7. Human platelet‐derived growth factor A chain is transcriptionally repressed by the Wilms' tumor suppressor WT1
8. Homozygous deletion in Wilms' tumours of a zinc‐finger gene identified by chromosome jumping
9. Molecular cloning and nucleotide sequence of a full‐length cDNA for human alpha enolase
10. An internal deletion within 11p13 zinc finger gene contributes to the development of Wilms' tumor
11. WT1‐mediated growth suppression of Wilms' tumor cells expressing a WT1 splicing variant
12. Alternative splicing and genomic structure of the Wilms' tumor gene WT1
13. Primary melanoma cells of the vertical growth phase: similarities to metastatic cells
14. Regulatory factors that determine growth and phenotype of normal melanocytes in culture
15. Characteristics of cultured human melanocytes isolated from different stages of tumor progression
16. Evidence for WT1 as a Wilms' tumor (WT) gene: intragenic germinal deletion in bilateral WT
17. Actin mRNAs in HeLa cells: stabilization after adenovirus infection
18. Development of invasive and growth factor‐independent cell variants from primary human melanomas
19. Cloning of a portion of the chromosomal gene for human erythrocyte α‐spectrin using a synthetic gene fragment
20. Zinc finger point mutations within the WT1 gene in Wilms' tumor patients
21. III, Transcriptional repression mediated by the WT1 Wilms' tumor gene product
22. Interaction between the p53 and Wilms' tumor (WT1) gene products: physical association and functional cooperation
23. Alternative splicing of the platelet‐derived growth factor‐A chain transcripts occurs in normal as well as tumor cells and is conserved among mammalian species
24. Expression of the Wilms' tumor gene (WT1) in human leukemias
25. Expression of the candidate Wilms' tumor gene in human leukemia cells
26. Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus
27. Evolution of the functional human β‐actin gene and its multi‐pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes
28. The Wilms tumour gene WT1 is expressed in murine mesoderm derived tissues and mutated in a human mesothelioma
29. Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys‐Drash syndrome
30. Expression of the Wilms' tumor gene WT1 in the murine urogenital system
31. Cell types expressing the Wilms' tumour gene (WT1) in Wilms' tumours: implications for tumour histogenesis
32. The candidate Wilms' tumour gene is involved in genitourinary development
33. Binding of the Wilms' tumor locus zinc finger protein to the EGR‐1 consensus sequence
34. Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes
35. The Wilms' tumor gene product. WT1, represses transcription of the platelet‐derived growth factor A‐chain gene
36. The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains
37. Mutation and expression of the p53 gene in malignant melanoma cell lines
38. Human melanoma cells of primary and metastatic origin express the genes encoding the constituent chains of PDGF and produce a PDGF‐like growth factor