Structure and mechanism of interleukin-lβ converting enzyme

Nature

Volumn 370, Issue 6487, 1994, Pages 270-275

  Wilson, Keith P ^a   Black, Jo Anne F ^a   Thomson, John A ^a   Kim, Eunice E ^a   Griffith, James P ^a   Navia, Manuel A ^a   Murcko, Mark A ^a   Chambers, Stephen P ^a   Aldape, Robert A ^a   Raybuck, Scott A ^a   Livingston, David J ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; CASPASE 1; CATALYSIS; CELL DEATH; CELL LINE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMAN; INTERLEUKIN-1; KINETICS; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS;

EID: 0028170376     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/370270a0     Document Type: Article

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