-
1
-
-
0023881236
-
Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
-
Pegg, A. E., Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res. 48: 759-774, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 759-774
-
-
Pegg, A.E.1
-
2
-
-
0003694527
-
-
Biological Significance and Basis for New Therapies. Orlando, FL: Academic Press
-
McCann, P. P., Pegg, A. E., and Sjoerdsma, A. Inhibition of Polyamine Metabolism. Biological Significance and Basis for New Therapies. Orlando, FL: Academic Press, 1987.
-
(1987)
Inhibition of Polyamine Metabolism.
-
-
McCann, P.P.1
Pegg, A.E.2
Sjoerdsma, A.3
-
3
-
-
12144263003
-
Polyamine levels in red blood cells of subjects receiving α-difluoromethylornithine in a phase I chemoprevention study
-
In: R.H. Dowling, U. R., Folsch, and C, Loser (eds.), Dordrecht, the Netherlands: Kluwer Academic Publishers
-
Pendyala, L. Creaven, P. J., and Porter, C. W., Polyamine levels in red blood cells of subjects receiving α-difluoromethylornithine in a phase I chemoprevention study. In: R.H. Dowling, U. R., Folsch, and C, Loser (eds.), Falk Symposium on Poly-amines in the Gastrointestinal Tract, pp. 193-202. Dordrecht, the Netherlands: Kluwer Academic Publishers, 1992.
-
(1992)
Falk Symposium on Poly-amines in the Gastrointestinal Tract
, pp. 193-202
-
-
Pendyala, L.1
Creaven, P.J.2
Porter, C.W.3
-
4
-
-
0026667443
-
Treatment of recurrent gliomas with eflornithine
-
Levin, V. A., Prados, M. D., Yung, W. K., Gleason, M. J., Ictech, S. and Malec, M. Treatment of recurrent gliomas with eflornithine. J. Natl. Cancer Inst. 84: 1432-1437, 1992.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1432-1437
-
-
Levin, V.A.1
Prados, M.D.2
Yung, W.K.3
Gleason, M.J.4
Ictech, S.5
Malec, M.6
-
5
-
-
0024374562
-
Treatment of recurrent gliomas with l, 3-bis(2-chloroethyl)-l-nitrosourea and α-difluoromethylornithine
-
Prados, M. Rodriguez, L. Chamberlain, M. Silver, P. and Levin, V. Treatment of recurrent gliomas with l, 3-bis(2-chloroethyl)-l-nitrosourea and α-difluoromethylornithine. Neurosurgery (Baltimore), 24: 806-809, 1989.
-
(1989)
Neurosurgery (Baltimore)
, vol.24
, pp. 806-809
-
-
Prados, M.1
Rodriguez, L.2
Chamberlain, M.3
Silver, P.4
Levin, V.5
-
6
-
-
0001054364
-
Clinical aspects of inhibition of ornithine decarboxylase with emphasis on therapeutic trials of eflornithine (DFMO) in cancer and protozoan diseases
-
In: P.P. McCann, A. E., Pegg, and A. Sjoerdsma (eds.), Orlando, FL: Academic Press
-
Schechter, P. J., Barlow, J.L.R. and Sjoerdsma, A. Clinical aspects of inhibition of ornithine decarboxylase with emphasis on therapeutic trials of eflornithine (DFMO) in cancer and protozoan diseases. In: P.P. McCann, A. E., Pegg, and A. Sjoerdsma (eds.), Inhibition of Polyamine Metabolism. Biological Significance and Basis for New Therapies, pp. 345-364. Orlando, FL: Academic Press, 1987.
-
(1987)
Inhibition of Polyamine Metabolism. Biological Significance and Basis for New Therapies
, pp. 345-364
-
-
Schechter, P.J.1
Barlow, J.L.R.2
Sjoerdsma, A.3
-
7
-
-
0023223138
-
Relative abilities of bis(ethyl)derivatives of putrescine, spermidine and spermine to regulate polyamine biosynthesis and inhibit cell growth
-
Porter, C. W., McManis, J. Casero, R. A., and Bergeron, R. J., Relative abilities of bis(ethyl)derivatives of putrescine, spermidine and spermine to regulate polyamine biosynthesis and inhibit cell growth. Cancer Res. 47: 2821-2825, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 2821-2825
-
-
Porter, C.W.1
McManis, J.2
Casero, R.A.3
Bergeron, R.J.4
-
8
-
-
0023923949
-
Synthetic polyamine analogues as antineoplastics
-
Bergeron, R. J., Neims, A. H., McManis, J. S., Hawthorne, T. R., Vinson, J. R., Bortell, R. and Ingeno, M. J., Synthetic polyamine analogues as antineoplastics. J. Med. Chem. 31: 1183-1190, 1988.
-
(1988)
J. Med. Chem.
, vol.31
, pp. 1183-1190
-
-
Bergeron, R.J.1
Neims, A.H.2
McManis, J.S.3
Hawthorne, T.R.4
Vinson, J.R.5
Bortell, R.6
Ingeno, M.J.7
-
9
-
-
45549113005
-
Enzyme regulation as an approach to interference with polyamine biosynthesis-an alternative to enzyme inhibition
-
In: G. Weber (ed.), New York: Pergamon Press
-
Porter, C. W., and Bergeron, R. J., Enzyme regulation as an approach to interference with polyamine biosynthesis-an alternative to enzyme inhibition. In: G. Weber (ed.), Advances in Enzyme Regulation, Vol. 27, pp. 57-79. New York: Pergamon Press, 1988.
-
(1988)
Advances in Enzyme Regulation
, vol.27
, pp. 57-79
-
-
Porter, C.W.1
Bergeron, R.J.2
-
10
-
-
0025331977
-
Polyamine analogues with antitumor activity
-
Edwards, M. L., Prakash, N. J., Stemerick, D. M., Sunkara, S. P., Bitonti, A. J., Davis, G. F., Dumont, J. A., and Bey, P. Polyamine analogues with antitumor activity. J. Med. Chem. 33: 1369-1375, 1990.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 1369-1375
-
-
Edwards, M.L.1
Prakash, N.J.2
Stemerick, D.M.3
Sunkara, S.P.4
Bitonti, A.J.5
Davis, G.F.6
Dumont, J.A.7
Bey, P.8
-
11
-
-
0025752595
-
Implications and concepts of polyamine-nucleic acid interactions
-
Feuerstein, B. G., Williams, L. D., Basu, H. S., and Marton, L. J., Implications and concepts of polyamine-nucleic acid interactions. J. Cell. Biochem. 46: 37-47, 1991.
-
(1991)
J. Cell. Biochem.
, vol.46
, pp. 37-47
-
-
Feuerstein, B.G.1
Williams, L.D.2
Basu, H.S.3
Marton, L.J.4
-
12
-
-
0027338998
-
Antitumor activity of N1, N11,-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action
-
Porter, C. W., Bernacki, R. Miller, J. and Bergeron, R. J., Antitumor activity of N1, N11,-bis(ethyl)norspermine against human melanoma xenografts and possible biochemical correlates of drug action. Cancer Res. 53: 581-586, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 581-586
-
-
Porter, C.W.1
Bernacki, R.2
Miller, J.3
Bergeron, R.J.4
-
13
-
-
0025195080
-
Effect of N1, Nl4-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells
-
Basu, H. S., Pellarin, M. Feuerstein, B. G., Deen, D. F., Bergeron, R. J., and Marton, L. J., Effect of N1, Nl4-bis(ethyl)homospermine on the growth of U-87 MG and SF-126 human brain tumor cells. Cancer Res. 50: 3137-3140, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 3137-3140
-
-
Basu, H.S.1
Pellarin, M.2
Feuerstein, B.G.3
Deen, D.F.4
Bergeron, R.J.5
Marton, L.J.6
-
14
-
-
0026634827
-
Antitumor effects of N-alkylated polyamine analogues in human pancreatic adenocarcinoma models
-
Chang, B. K., Bergeron, R. J., Porter, C. W., and Liang, Y. Antitumor effects of N-alkylated polyamine analogues in human pancreatic adenocarcinoma models. Cancer Chemother. Pharmacol. 30: 179-182, 1992.
-
(1992)
Cancer Chemother. Pharmacol.
, vol.30
, pp. 179-182
-
-
Chang, B.K.1
Bergeron, R.J.2
Porter, C.W.3
Liang, Y.4
-
15
-
-
0026647229
-
Antitumor activity of N, N1-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts
-
Bernacki, R. J., Bergeron, R. J., and Porter, C. W., Antitumor activity of N, N1-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer Res. 52: 2424-2430, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 2424-2430
-
-
Bernacki, R.J.1
Bergeron, R.J.2
Porter, C.W.3
-
16
-
-
0023110045
-
Regulation of ornithine decarboxylase activity by spermidine and the spermidine analog, N1, N8-bis(ethyl)spermidine (BES)
-
Porter, C. W., Berger, F. G., Pegg, A. E., Ganis, B. and Bergeron, R. J., Regulation of ornithine decarboxylase activity by spermidine and the spermidine analog, N1, N8-bis(ethyl)spermidine (BES). Biochem. J. 242: 433-440, 1987.
-
(1987)
Biochem. J.
, vol.242
, pp. 433-440
-
-
Porter, C.W.1
Berger, F.G.2
Pegg, A.E.3
Ganis, B.4
Bergeron, R.J.5
-
17
-
-
0026757186
-
Induction of spermidine/spermine N1-acetyltransferase (SSAT) steady-state messenger RNA and activity correlates with sensitivity to N1, N12-bis(ethyI)spermine in human cell lines representing the major forms of lung cancer
-
Casero, R. A., Jr. Mank, A. R., Xiao, L. Smith, J. Bergeron, R. J., and Celano, P. Induction of spermidine/spermine N1-acetyltransferase (SSAT) steady-state messenger RNA and activity correlates with sensitivity to N1, N12-bis(ethyI)spermine in human cell lines representing the major forms of lung cancer. Cancer Res. 52: 5359-5363, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 5359-5363
-
-
Casero, R.A.1
Mank, A.R.2
Xiao, L.3
Smith, J.4
Bergeron, R.J.5
Celano, P.6
-
18
-
-
0023663619
-
A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interaction
-
Basu, H. S., Shafer, R. H., and Marton, L. J., A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interaction. Nucleic Acids Res. 75: 5873-5886, 1987.
-
(1987)
Nucleic Acids Res.
, vol.75
, pp. 5873-5886
-
-
Basu, H.S.1
Shafer, R.H.2
Marton, L.J.3
-
19
-
-
0023742975
-
Different binding modes of spermine to A-T and G-C base pairs modulate the bending and stiffening of the DNA double helix
-
Marquet, R. and Houssier, C. Different binding modes of spermine to A-T and G-C base pairs modulate the bending and stiffening of the DNA double helix. J. Biomol. Struct. Dyn. 6: 235-246, 1988.
-
(1988)
J. Biomol. Struct. Dyn.
, vol.6
, pp. 235-246
-
-
Marquet, R.1
Houssier, C.2
-
20
-
-
0017238490
-
Compact form of DNA induced by spermidine
-
Gosule, L. C., and Schellman, J. A., Compact form of DNA induced by spermidine. Nature (Lond.), 259: 333-335, 1976.
-
(1976)
Nature (Lond.)
, vol.259
, pp. 333-335
-
-
Gosule, L.C.1
Schellman, J.A.2
-
21
-
-
0022531432
-
Condensation of chromatin. Role of multivalent cations
-
Sen, D. and Crothers, D. M., Condensation of chromatin. Role of multivalent cations. Biochemistry, 25: 1495-1503, 1986.
-
(1986)
Biochemistry
, vol.25
, pp. 1495-1503
-
-
Sen, D.1
Crothers, D.M.2
-
22
-
-
0023230920
-
The interaction of spermine and pentamines with DNA
-
Basu, H. S., and Marton, L. J., The interaction of spermine and pentamines with DNA. Biochem J. 244: 243-246, 1987.
-
(1987)
Biochem J.
, vol.244
, pp. 243-246
-
-
Basu, H.S.1
Marton, L.J.2
-
23
-
-
0025149018
-
A polarized photobleaching study of chromatin reorientation in intact nuclei
-
Selvin, P. R., Scalettar, B. A., Langmore, J. P., Axelrod, M. D., Klein, M. P., and Hearst, J. E., A polarized photobleaching study of chromatin reorientation in intact nuclei. J. Mol. Biol. 214: 911-922, 1990.
-
(1990)
J. Mol. Biol.
, vol.214
, pp. 911-922
-
-
Selvin, P.R.1
Scalettar, B.A.2
Langmore, J.P.3
Axelrod, M.D.4
Klein, M.P.5
Hearst, J.E.6
-
24
-
-
0026519141
-
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumor cells
-
Basu, H. S., Sturkenboom, M.C.J.M. Delcros, J. G., Csokan, P. P., Szollosi, J. Feuerstein, B. G., and Marton, L. J., Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumor cells. Biochem. J. 283: 723-727, 1992.
-
(1992)
Biochem. J.
, vol.283
, pp. 723-727
-
-
Basu, H.S.1
Sturkenboom, M.C.J.M.2
Delcros, J.G.3
Csokan, P.P.4
Szollosi, J.5
Feuerstein, B.G.6
Marton, L.J.7
-
25
-
-
0027299710
-
Treatment with polyamine analog alters DNA-matrix association in HeLa cell nuclei: a nucleoid halo assay
-
Basu, H. S., Wright, W. D., Deen, D. F., Roti-Roti, J. and Marton, L. J., Treatment with polyamine analog alters DNA-matrix association in HeLa cell nuclei: a nucleoid halo assay. Biochemistry, 32: 4073-4076, 1993.
-
(1993)
Biochemistry
, vol.32
, pp. 4073-4076
-
-
Basu, H.S.1
Wright, W.D.2
Deen, D.F.3
Roti-Roti, J.4
Marton, L.J.5
-
26
-
-
0025281643
-
Effect of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes
-
Basu, H. S., Schweitert, H.C.A. Feuerstein, B. G., and Marton, L. J., Effect of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. Biochem. J. 269: 329-334, 1990.
-
(1990)
Biochem. J.
, vol.269
, pp. 329-334
-
-
Basu, H.S.1
Schweitert, H.C.A.2
Feuerstein, B.G.3
Marton, L.J.4
-
27
-
-
0024416719
-
Correlation between the effects of polyamine analogs on DNA conformation and cell growth
-
Basu, H. S., Feuerstein, B. G., Deen, D. F., Lubich, W. P., Bergeron, R. J., Samejima, K. and Marton, L. J., Correlation between the effects of polyamine analogs on DNA conformation and cell growth. Cancer Res. 49: 5591-5597, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5591-5597
-
-
Basu, H.S.1
Feuerstein, B.G.2
Deen, D.F.3
Lubich, W.P.4
Bergeron, R.J.5
Samejima, K.6
Marton, L.J.7
-
28
-
-
0027213483
-
Interaction of a polyamine analogue, l, 19-bis(ethylamino)-5, 10, 15-triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines
-
Basu, H. S., Pellarin, M. Feuerstein, B. G., Shirahata, A. Samejima, K. Deen, D. F., and Marton, L. J., Interaction of a polyamine analogue, l, 19-bis(ethylamino)-5, 10, 15-triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. Cancer Res. 53: 3948-3955, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3948-3955
-
-
Basu, H.S.1
Pellarin, M.2
Feuerstein, B.G.3
Shirahata, A.4
Samejima, K.5
Deen, D.F.6
Marton, L.J.7
-
29
-
-
0019811630
-
Potentiation of the antitumor therapeutic effects of l, 3-bis(2-chloro-ethyl)-l-nitrosourea by a-difluoromethylornithine, an ornithine decarboxylase inhibitor
-
Marton, L. J., Levin, V. A., Hervatin, S. J., Koch-Weser, J. McCann, P. P., and Sjoerdsma, A. Potentiation of the antitumor therapeutic effects of l, 3-bis(2-chloro-ethyl)-l-nitrosourea by a-difluoromethylornithine, an ornithine decarboxylase inhibitor. Cancer Res. 41: 4426-4431, 1981.
-
(1981)
Cancer Res.
, vol.41
, pp. 4426-4431
-
-
Marton, L.J.1
Levin, V.A.2
Hervatin, S.J.3
Koch-Weser, J.4
McCann, P.P.5
Sjoerdsma, A.6
-
30
-
-
0017137661
-
Single-agent chemotherapy of brain tumors. A five-year review
-
Wilson, C. B., Gutin, P. H., Boldrey, E. B., Crafts, D. Levin, V. A., and Enot, K. J., Single-agent chemotherapy of brain tumors. A five-year review. Arch. Neurol. 33: 739-744, 1976.
-
(1976)
Arch. Neurol.
, vol.33
, pp. 739-744
-
-
Wilson, C.B.1
Gutin, P.H.2
Boldrey, E.B.3
Crafts, D.4
Levin, V.A.5
Enot, K.J.6
-
31
-
-
0024354304
-
Determination of subcutaneous tumor size in athymic (nude) mice
-
Tomaydo, M. M., and Reynolds, C. P., Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother. Pharmacol. 24: 148-154, 1989.
-
(1989)
Cancer Chemother. Pharmacol.
, vol.24
, pp. 148-154
-
-
Tomaydo, M.M.1
Reynolds, C.P.2
-
32
-
-
0026610238
-
Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to l, 3-bis(2-chloroethyl)-l-nitrosourea and on DNA intrastrand cross-link formation
-
Mitchell, R. B., Moschel, R. C., and Dolan, M. E., Effect of O6-benzylguanine on the sensitivity of human tumor xenografts to l, 3-bis(2-chloroethyl)-l-nitrosourea and on DNA intrastrand cross-link formation. Cancer Res. 52: 1171-1175, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1171-1175
-
-
Mitchell, R.B.1
Moschel, R.C.2
Dolan, M.E.3
-
33
-
-
0024311954
-
Differential induction of spermidine/spermine N1-acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues
-
Casero, R. A., Jr. Celano, P. Ervin, S. J., Porter, C. W., Bergeron, R. J., and Libby, P. R., Differential induction of spermidine/spermine N1-acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues. Cancer Res. 49: 3829-3833, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 3829-3833
-
-
Casero, R.A.1
Celano, P.2
Ervin, S.J.3
Porter, C.W.4
Bergeron, R.J.5
Libby, P.R.6
-
34
-
-
0027081149
-
Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs
-
Ghoda, L. Basu, H. S., Porter, C. W., Marton, L. J., and Coffino, P. Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs. Mol. Pharmacol. 42: 302-306, 1992.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 302-306
-
-
Ghoda, L.1
Basu, H.S.2
Porter, C.W.3
Marton, L.J.4
Coffino, P.5
-
35
-
-
0027512683
-
Investigations of the mechanism by which mammalian cell growth is inhibited by N1, N12-bisfcthyl)spermine
-
Albanese, L. Bergeron, R. J., and Pegg, A. E., Investigations of the mechanism by which mammalian cell growth is inhibited by N1, N12-bisfcthyl)spermine. Biochem. J. 291: 131-137, 1993.
-
(1993)
Biochem. J.
, vol.291
, pp. 131-137
-
-
Albanese, L.1
Bergeron, R.J.2
Pegg, A.E.3
|