SR-4233 (Tirapazamine) acts as an uncoupler of oxidative phosphorylation in human MCF-7 breast carcinoma cells

Cancer Letters

Volumn 85, Issue 2, 1994, Pages 195-203

  Ara, Gulshan ^a,b   Coleman, C Norman ^a,b   Teicher, Beverly A ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD RADIATION ONCOLOGY PROGRAM   (United States)

Author keywords

Breast cancer; Hypoxic cell selective cytoxins; Mitochondrial cytotoxins; SR 4233; Tirapazamine

Indexed keywords

MINK CELL FOCUS-FORMING VIRUS;

ADENOSINE TRIPHOSPHATE; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CYTOTOXIC AGENT; OLIGOMYCIN; ROTENONE; TIRAPAZAMINE;

ARTICLE; BREAST CARCINOMA; CELL KILLING; CELL STRAIN MCF 7; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIC CELL; MUSCLE CRAMP; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXYGEN CONSUMPTION; OXYGEN ELECTRODE; OXYGENATION; PHASE 1 CLINICAL TRIAL; POLAROGRAPHY; PRIORITY JOURNAL;

ADENOCARCINOMA; BREAST NEOPLASMS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CYTOCHROME-C OXIDASE; FEMALE; HUMAN; IN VITRO; OXYGEN CONSUMPTION; SUPPORT, U.S. GOV'T, P.H.S.; TRIAZINES; TUMOR CELLS, CULTURED; UNCOUPLING AGENTS;

EID: 0028168183     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(94)90275-5     Document Type: Article

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