Apolipoprotein e ε4 allele in alzheimer's disease and vascular dementia

Dementia and Geriatric Cognitive Disorders

Volumn 5, Issue 5, 1994, Pages 240-242

  Frisoni, Giovanni B ^a   Calabresi, Laura ^b   Geroldi, Cristina ^a   Bianchetti, Angelo ^a   D'Acquarica, Antonio L ^b   Govoni, Stefano ^c   Sirtori, Cesare R ^b   Trabitcchi, Marco ^a   Franceschini, Guido ^b  

^a GERIATRIC RESEARCH GROUP   (Italy)

^b Dipartimento di Scienze Farmacologiche e Biomolecolari   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Alzheimer s disease; Apolipoprotein E; Dementia of frontal type; Vascular dementia

Indexed keywords

APOLIPOPROTEIN E;

ALLELE; ALZHEIMER DISEASE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; MULTIINFARCT DEMENTIA; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; ADULT; AGED; GENETICS;

ADULT; AGED; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; DEMENTIA, VASCULAR; HUMAN; MIDDLE AGE; RISK FACTORS; SUPPORT, NON-U.S. GOV'T;

EID: 0028167816     PISSN: 14208008     EISSN: 14219824     Source Type: Journal    
DOI: 10.1159/000106730     Document Type: Article

References (10)

1. Saunders AM, Strittmaller WJ, Schmcchel D, St. George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella GF, Crapper-MacLach-lan DR, Alberts MJ, Hulette C, Crain B, Goldgaber D, Roses AD: Association of apoli-poprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disase. Neurology 1993;43:1467-1472.
2. Strittmatter WJ, Saunders AM. Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD: Apolipoprotein E: High avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993:90: 1977-1981.
3. Scott J: Apolipoprotein E and Alzheimer's disease. Lancet 1993:342:696.
4. McKhann G, Drachman D, Folstein MF, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group. Neurology 1984;34:939-944.
5. Roman GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdcu JC, Garcia JH, Amad- ucci L, Orgogozo J-M, Brun A, Hofman A, Moody DM. O'Brien MD, Yamaguchi T, Graf- man J, Drayer PB, Bennett DA, Fisher M, Ogata J, Kokmcn E, Bcrmcjo F, Wolf PA, Gorelick PB, Bick KL, Pajeau AK, Bell MA, DeCarli C, Culabras A, Korczyn AD, Bogousslavski J, Hartmann A, Scheinberg P: Vascular dementia: Diagnostic criteria for research studies: Report of the NINDS-AIREN International Workshop. Neurology 1993;43:250-260.
6. Gustafson L: Frontal lobe degeneration of non- Alzheimer type. II. Clinical picture and differential diagnosis. Arch Gerontol Geriatr 1987;6: 209-223.
7. Kohlmeier M, Drossel H, Sinha P, Kottgen E: Rapid and simple method for the identification of apoE isomorphic phenotype from whole serum. Electrophoresis 1992;13:258-263.
8. Gabelli C, Martini S, Barbato GM, Baggio G, Corti MC, Opportuno A, Bilato C, Crepaldi G: Allelic distribution of apolipoprotein E isoforms in northern Italv. J Drug Dev 1990;3:63-68.
9. Noguchi S, Murakami K, Yamada N: Apolipoprotein E genotype and Alzheimer’s disease. Lancet 1993;342:737.
10. Ignatius MJ, Schootcr EM, Pitas RE, Mahley RW: Lipoprotein uptake by neuronal growth cones in vitro. Science 1987;236:959-962.