MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

Current Opinion in Genetics and Development

Volumn 4, Issue 1, 1994, Pages 82-89

  Marshall, Christopher J ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; ENZYME ACTIVATOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN P21; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

CELL MEMBRANE; CELL NUCLEUS; CYTOPLASM; ENZYME ACTIVATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION;

ANIMAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME ACTIVATION; HUMAN; MAP KINASE KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

EUKARYOTA; SCHIZOSACCHAROMYCES POMBE;

EID: 0028152333     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-437X(94)90095-7     Document Type: Article

References (87)

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2. Signal Transduction via the MAP Kinases: Proceed at your own RSK
3. Mitogen-Activated Protein Kinases: Versatile Transducers for Cell Signaling
4. ERKs: A Family of Protein-Serine/Threonine Kinases That Are Activated and Tyrosine Phosphorylated in Response to Insulin and NGE
5. cPLA2 is Phosphorylated and Activated by MAP Kinase
6. Structure, Expression and Regulation of Protein Kinases Involved in the Phosphorylation of Ribosomal Protein S6
7. MAPKAP Kinase-2; a Novel Protein Kinase Activated by Mitogen-Activated Protein Kinase
8. 2-Terminal Domain of c-Myc Increases Transactivation of Gene Expression
9. Phosphorylation of c-Jun Mediated by MAP Kinases
10. The Yeast STE12 Protein Binds to the DNA Sequence Mediating Pheromone Induction
11. Nuclear Localization and Regulation of erk- and rsk-Encoded Protein Kinases
12. mapk) in Fibroblasts
13. A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf
14. A Gene which Encodes a Predicted Protein Kinase can Restore some Functions of the Ras Gene in Fission Yeast
15. Byr2, a Schizosaccharomyces pombe Gene Encoding a Protein Kinase Capable of Partial Suppression of the Ras1 Mutant Phenotype
16. Order of Action of Components in the Yeast Pheromone Response Pathway Revealed with a Dominant Allele of the STE11 Kinase and the Multiple Phosphorylation of the STE7 Kinase
17. STE11 is a Protein Kinase Required for Cell-Type-Specific Transcription and Signal Transduction in Yeast
18. Constitutive Mutants of the Protein Kinase STE11 Activate the Yeast Pheromone Response Pathway in the Absence of the G Protein
19. MAP Kinase-Related FUS3 from S. cerevisiae is Activated by STE7 In Vitro
20. A Yeast Mitogen-Activated Protein Kinase Homolog (Mpk1p) Mediates Signalling by Protein Kinase C
21. MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase
22. An Osmosensing Signal Transduction Pathway in Yeast
23. Complementation of byr1 in Fission Yeast by Mammalian MAP Kinase Kinase Requires Coexpression of Raf Kinase
24. Novel Members of the Mitogen-Activated Protein Kinase Activator Family in Xenopus laevis
25. Functional Homology of Protein Kinases Required for Sexual Differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae Suggests a Conserved Signal Transduction Module in Eukaryotic Organisms
26. Schizosaccharomyces pombe spk1 is a Tyrosine-Phosphorylated Protein Functionally Related to Xenopus Mitogen Activated Protein Kinase
27. Requirements for Integration of Signals from Two Distinct Phosphorylation Pathways for Activation of MAP Kinase
28. MAP Kinase Activator from Insulin-Stimulated Skeletal Muscle is a Protein Threonine/Tyrosine Kinase
29. Xenopus MAP Kinase Activator is a Serine/Threonine/Tyrosine Kinase Activated by Threonine Phosphorylation
30. Identification of the Regulatory Phosphorylation Sites in pp42/Mitogen-Activated Protein Kinase (MAP Kinase)
31. The Primary Structure of MEK, a Protein Kinase That Phosphorylates the ERK Gene Product
32. The Amino Acid Sequence of a Mammalian MAP Kinase Kinase
33. A Protein Kinase Similar to MAP Kinase Activator Acts Downstream of the Raf Kinase in Drosophila
34. cDNA Cloning of MAP Kinase Kinase Reveals Kinase Cascade Pathways in Yeasts to Vertebrates
35. Identification and Characterization of a New Mammalian Mitogen-Activated Protein Kinase Kinase, MKK2
36. Isolation of Two Members of the Rat MAP Kinase Kinase Gene Family
37. Cloning and Characterization of Two Distinct Human Extracellular Signal-Regulated Kinase Activator Kinases, MEK1 and MEK2
38. Human T-Cell Mitogen-Activated Protein Kinase Kinases are Related to Yeast Signal Transduction Kinases
39. Phosphorylation of Xenopus Mitogen-Activated Protein (MAP) Kinase Kinase by MAP Kinase Kinase Kinase and MAP Kinase
40. Molecular Structure of a Protein-Tyrosine/Threonine Kinase Activating p42 Mitogen-Activated Protein (MAP) Kinase: MAP Kinase Kinase
41. mapk by MAP Kinase Kinase
42. Requirements for Phosphorylation of MAP Kinase During Meiosis in Xenopus Oocytes
43. Dissection of the Protein Kinase Cascade by which Nerve Growth Factor Activates MAP Kinases
44. Raf-1 Activates MAP Kinase-Kinase
45. Activation of the MAP Kinase Pathway by the Protein Kinase Raf
46. Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and In Vitro
47. Reconstitution of the Raf-1-MEK-ERK Signal Transduction Pathway In Vitro
48. Complex Formation Between RAS and RAF and Other Protein Kinases
49. A Protein Factor for ras p21-Dependent Activation of Mitogen-Activated Protein (MAP) Kinase Through MAP Kinase Kinase
50. ras
51. raf-1
52. i-Coupled Acetylcholine Muscarinic m2 Receptor Activation of Mitogen-activated Protein (MAP) Kinase Kinase and MAP Kinase
53. Requirement for c-ras Proteins During Viral Oncogene Transformation
54. Serum-, TPA-, and Ras-Induced Expression from Ap-1/Ets-Driven Promoters Requires Raf-1 Kinase
55. Ras Mediates Nerve Growth Factor Receptor Modulation of Three Signal-Transducing Protein Kinases: MAP Kinase, Raf-1, and RSK
56. Mammalian Ras Interacts Directly with the Serine/Threonine Kinase Raf
57. Direct Interaction of Ras and the Amino-Terminal Region of Raf-1 In Vitro
58. ras Proteins Bind to the Amino-Terminal Regulatory Domain of c-Raf-1
59. v-src are Required, But Neither Alone is Sufficient, to Activate the Raf-1 Kinase
60. The Protein Kinase Homologue Ste20p is Required to Link the Yeast Pheromone Response G-Protein βγ Subunits to Downstream Signalling Components
61. A Dominant Truncation Allele Identifies a Gene, STE20, that Encodes a Putative Protein Kinase Necessary for Mating in Saccharomyces cerevisiae
62. Dominant Mutations in a Gene Encoding a Putative Protein Kinase (BCK1) Bypass the Requirement for a Saccharomyces cerevisiae Protein Kinase C Homolog
63. Interleukin 2 Regulates Raf-1 Kinase Activity Through a Tyrosine Phosphorylation-Dependent Mechanism in a T-Cell Line
64. Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase
65. Identification of the Major Phosphorylation Sites of the Raf-1 Kinase
66. Activation of the c-Raf Protein Kinase by Protein Kinase C Phosphorylation
67. Protein Kinase Cα Activates Raf-1 by Direct Phosphorylation
68. Requirements for Raf and MAP Kinase Function during the Meiotic Maturation of Xenopus Oocytes
69. Raf-1 Protein Kinase Is Important for Progesterone-Induced Xenopus Oocyte Maturation and Acts Downstream of Mos
70. Insulin Activates the Kinase Activity of the raf-1 Proto-Oncogene by Increasing its Serin Phosphorylation
71. Specific Association of Activated MAP Kinase Kinase Kinase (Raf) with the Plasma Membrane of Ras-Transformed Retinal Cells
72. Raf-1 Protein Kinase Activates the NF-κB Transcription Factor by Dissociating the Cytoplasmic NF-κB-IκB Complex
73. Conditional Transformation of Cells and Rapid Activation of the Mitogen-Activated Protein Kinase Cascade by an Estradiol-Dependent Human Raf-1 Protein Kinase
74. cAMP Antagonizes p21ras Directed Activation of Extracellular Signal-Regulated Kinase 2 and Phosphorylation of mSos Nucleotide Exchange Factor
75. Inhibition of cAMP of Ras-Dependent Activation of Raf
76. Inhibition of the EGF-Activated MAP Kinase Signalling Pathway by Adenosine 3′,5′-Monophosphate
77. Complexes of Ras-GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase
78. Extracellular Signals and Reversible Protein Phosphorylation: What to Mek of It All
79. Activation of Extracellular Signal-Regulated Kinase, ERK2, by p21ras Oncoprotein
80. The Post-Translational Processing of ras p21 is Critical for its Stimulation of Mitogen-Activated Protein Kinase
81. mapk are Required for Fibroblast Proliferation
82. The Human CL100 Gene Encodes a Tyr/Thr-Protein Phosphatase which Potently and Specifically Inactivates MAP Kinase and Suppresses its Activation by Oncogenic Ras in Xenopus Oocyte Extracts.
83. MKP-1 (3CH134), an Immediate Early Gene Product, Is a Dual Specificity Phosphatase That Dephosphorylates MAP Kinase In Vivo
84. Oxidative Stress and Heat Shock Induce a Human Gene Encoding a Protein-Tyrosine Phosphatase
85. cDNA Sequence of a Growth Factor-Inducible Immediate Early Gene and Characterization of Its Encoded Protein
86. A Mitogen-Induced Nuclear Protein Tyrosine Phosphatase
87. Sustained Activation of the Mitogen-Activated Protein (MAP) Kinase Cascade may be Required for Differentiation of PC12 Cells