WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties

The Journal of Antibiotics

Volumn 47, Issue 10, 1994, Pages 1084-1091

  Iwamoto, Toshiro ^a   Fujie, Akihiko ^a   Sakamoto, Kazutoshi ^a   Tsurumi, Yasuhisa ^a   Shigematsu, Nobuharu ^a   Yamashita, Michio ^a   Hashimoto, Seiji ^a   Okuhara, Masakuni ^a   Kohsaka, Masanobu ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ECHINOCANDIN B DERIVATIVE; UNCLASSIFIED DRUG; WF 11899 A; WF 11899 B; WF 11899 C;

ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CONTROLLED STUDY; DRUG ISOLATION; DRUG SOLUBILITY; FEMALE; FUNGUS CULTURE; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ANIMAL; ANTIFUNGAL AGENTS; CANDIDA; CHEMISTRY, PHYSICAL; FEMALE; FERMENTATION; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED ICR; MITOSPORIC FUNGI; PEPTIDES, CYCLIC; SOLUBILITY;

EID: 0028148980     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.47.1084     Document Type: Article

References (15)

1. Benz, F.; F. Knuel, J. Nuesch, H. Treichler & W. Voser: Echinocandin B, ein neuartiges Polipeptid-Antibiotikum aus Aspergillus nidulans var. echinatus: Isolierung und Bausteine. Helv. Chim. Acta 57: 2459~2477, 1974.
2. Mizuno, K.; A. Yagi, S. Satoi, M. Takada, M. Hayashi, K. Asano & T. Matsuda: Studies on aculeacin. I. Isolation and characterization of aculeacin A. J. Antibiotics 30: 297~302, 1977.
3. Roy, K.; T. Mukhopadhyay, G. C. S. Reddy, K. R. Desikan & B. N. Ganguli: Mulundocandin, a new lipopeptide antibiotic. I. Taxonomy, fermentation, isolation and characterization. J. Antibiotics 40: 275~280, 1987.
4. Schwartz, R. E.; D. F. Sesin, H. Joshua, K. E. Wilson, A. J. Kempf, K. A. Goklen, D. Kuehner, P. Gailliot, C. Gleason, R. White, E. Inamine, G. Bills, P. Salmon & L. Zitano: Pneumocandins from Zalerion arboricola. I. Discovery and isolation. J. Antibiotics 45: 1853~1866, 1992.
5. Schwartz, R. R.; R. A. Giacobbe, J. A. Bland & R. L. Monaghan: L-67 1,329, A new antifungal agent. I. Fermentation and isolation. J. Antibiotics 42: 163~167, 1989.
6. Schmatz, D. M.; G. Abruzzo, M. A. Powles, D. C. Mcfadden, J. M. Balkovec, R. M. Black, K. Nollstadt & K. Bartizal: Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species. J. Antibiotics 45: 1886~1891, 1992.
7. Iwamoto, T.; K. Sakamoto, M. Yamashita, M. Ezaki, S. Hashimoto, T. Furuta, M. Okuhara & M. Kohsaka: FR901379, a novel antifungal antibiotic. Program and Abstracts of the 33rd Intersci. Conf. on Antimicrob. Agents Chemother., No. 371, pp. 187, New Orleans, Oct. 17~20, 1993.
8. Kornerup, A & J. H. Wanscher: Methuen Handbook of Colour (3rd. ed.), pp. 252., Methuen, London, 1983.
9. Miura, K. & M. Y. Kudo: An agar-medium for aquatic Hyphomycetes. Trans. Mycolo. Soc. Japan, 11: 116~118, 1970.
10. Arx, J. A. Von: The Genera of Fungi - Sporulating in Pure Culture (3rd. ed.), pp. 315, J. Cramer, Vaduz, 1974.
11. Sutton, B. C.: The Coelomycetes - Fungi Imperfecti with Pycnidia, Acervuli and Stromata., pp. 696, Commonwealth Mycological Institute, Kew., 1980.
12. Hawksworth, D. L.; B. C. Sutton & G. C. Ainsworth: Dictionary of the Fungi (7th. ed.), pp. 445, Commonwealth Mycological Institute, Kew., 1983.
13. Iwamoto, T.; A. Fujie, K. Nitta, S. Hashimoto, M. Okuhara & M. Kohsaka: WF11899A, B, and C, novel antifungal lipopeptides. II. Biological properties. J. Antibiotics 47: 1092~1097, 1994.
14. Balkovec, J. M.; R. M. Black, M. L. Hammond, J. V. Heck, R. A. Zambias, G. Abruzzo, K. Bartizal, H. Kropp, C. Trainor, R. E. Schwartz, D. C. Mcfadden, K. H. Nollstadt, L. A. Pittarelli, M. A. Powles & D. M. Schmatz: Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP). J. Med. Chem. 35: 194~198, 1992.
15. Bouffard, F. A.; R. A. Zambias, J. F. Dropinski, J. M. Balkovec, M. L. Hammond, K. H. Nollstadt & J. Marrinan: Synthesis and antifungal activity of water-soluble pneumocandin B0 derivatives. Program and Abstracts of the 33rd Intersci. Conf. on Antimicrob. Agents Chemother., No. 350, pp. 183, New Orleans, Oct. 17~20, 1993.