The helix-loop-helix gene E2A is required for B cell formation

Cell

Volumn 79, Issue 5, 1994, Pages 875-884

  Zhuang, Yuan ^a   Soriano, Philippe ^a   Weintraub, Harold ^a  

^a FRED HUTCHINSON CANCER RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; EMBRYO; ERYTHROID CELL; GRANULOCYTE; HOMOZYGOSITY; LYMPHOCYTOPOIESIS; MACROPHAGE; MOUSE; NEWBORN DEATH; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALIA;

EID: 0028148938     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(94)90076-0     Document Type: Article

References (54)

1. E2A and E2-2 are subunits of B-cell-specific E2-box DNA-binding proteins
2. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
3. The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif
4. The protein Id a negative regulator of helix-loop-helix DNA binding proteins
5. daughterless a Drosophila gene essential for both neurogenesis and sex determination has sequence similarities to myc and the achaete-scute complex
6. The Drosophila sex determination signal how do flies count to two?
7. Oct-2 although not required for early B-cell development is critical for later B-cell maturation and for postnatal survival
8. Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development
9. Targeted disruption of the Oct-2 locus in a B-cell provides genetic evidence for two distinct cell type-specific pathways of octamer element-mediated gene activation
10. The lkaros gene is required for the development of all lymphoid lineages
11. H element reading frames
12. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
13. Resolution and characterization of pro-B and pre-pro-B-cell stages in normal mouse bone marrow
14. Two transcription factors that bind the immunoglobulin enhancer μE5/kE2 motif
15. HEB a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors
16. HLH proteins fly neurogenesis and vertebrate myogenesis
17. Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells
18. Helix-loop-helix proteins in the regulation of immunoglobulin gene transcription
19. Id gene expression and its suppression by 125-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells
20. An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences
21. Transformation by activated ras or fos prevents myogenesis by inhibiting expression of MyoD1
22. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo
23. Xenogenic monoclonal antibodies to mouse lymphoid differentiation antigens
24. Thresholds in development
25. Functional overlap in the src gene family inactivation of hck and fgr impairs natural immunity
26. Disruption of the proto-oncogene int-2 in mouse embryonic stem cells a general strategy for targeting mutations of non-selectable genes
27. Cell surface antigens expressed by subsets of pre-B cells and B cells
28. The Wnt-1 (int-1) protonocogene is required for development of a large region of the mouse brain
29. RAG-1-deficient mice have no mature B and T lymphocytes
30. A new DNA binding and dimerization motif in immunoglobulin enhancer binding daughterless MyoD and myc proteins
31. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
32. Pan a transcription regulator that binds chymotrypsin insulin and AP-4 enhancer motifs
33. Fluorescence-activated cell analysis and sorting of viable mammalian cells based on β-d-galactosidase activity after transduction of Escherichia coli lac-Z
34. Molecular control of myogenesis: antagonism between growth and differentiation
35. Subunit structure of cell-specific E box-binding proteins analyzed by quantitation of electrophoresis mobility shift
36. XA ratio the primary sex-determining signal in Drosophila is transduced by helix-loop-helix proteins
37. Lymphocyte ontogeny and activation in gene targeted mutant mice
38. Localization of E2A mRNA expression in developing and adult rat tissues
39. B lymphopoiesis in the mouse
40. MyoD or Myf-5 is required for the formation of skeletal muscle
41. Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line
42. Virus-transformed pre-B-cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription
43. m1 mutation show poor viability and depletion of selected B and T-cell populations
44. The transcription factor PU1 is required for the development of multiple hematopoietic lineages
45. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
46. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
47. An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers
48. ADD1 a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
49. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
50. Mutations that disrupt DNA binding and dimerization in the E47 helix-loop-helix protein map to distinct domains
51. The MyoD family and myogenesis redundancy networks and thresholds
52. The MyoD gene family nodal point during specification of the muscle cell lineage
53. Repression of immunoglobulin enhancers by the helix-loop-helix protein Id implications for B lymphoid development
54. Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis erythropoiesis chondrogenesis and neurogenesis