Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec, Canada. Past, present and future

Science of the Total Environment, The

Volumn 154, Issue 2-3, 1994, Pages 201-215

  Martineau, D ^a   De Guise, S ^a,b   Fournier, M ^b   Shugart, L ^d   Girard, C ^a   Lagace A ^a   Beland P ^c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c Institut National d'Écotoxicologie du Saint Laurent ^*  (Canada)

^d OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Beluga; Cancer; Cetaceans; Contaminants; DDT; Hydrocarbons; Immunosuppression; Organochlorine; Pathology; PCB; Polycyclic Aromatic; Whales

Indexed keywords

4 AMINOHIPPURIC ACID; CHLORPHENOTANE; HEAVY METAL; ORGANOCHLORINE DERIVATIVE;

ANIMAL TISSUE; CANADA; CANCER; CONFERENCE PAPER; ENVIRONMENTAL IMPACT ASSESSMENT; ENVIRONMENTAL MONITORING; IMMUNE DEFICIENCY; NONHUMAN; PRIORITY JOURNAL; SEA POLLUTION; WATER POLLUTION; WHALE;

ANIMALS; DIGESTIVE SYSTEM DISEASES; DNA DAMAGE; FEMALE; HISTORY, 20TH CENTURY; MALE; NEOPLASMS; POLYCHLORINATED BIPHENYLS; QUEBEC; WATER POLLUTANTS, CHEMICAL; WATER POLLUTION, CHEMICAL; WHALES;

ANIMALIA; CETACEA; DELPHINAPTERUS; DELPHINAPTERUS LEUCAS; LEUCAS;

EID: 0028147008     PISSN: 00489697     EISSN: None     Source Type: Journal    
DOI: 10.1016/0048-9697(94)90088-4     Document Type: Article

References (100)

1. Catch history and initial population of white whales (Delphinapterus leucas) in the river and Gulf of St. Lawrence, eastern Canada
2. Potential for growth of the St. Lawrence (Quebec, Canada) beluga whale (Delphinapterus leucas) population based on modelling
3. Toxicology and Pathology of St Lawrence Marine Mammals
4. Transitional cell carcinoma of the urinary bladder in a beluga whale (Delphinapterus leucas)
5. Rupture of a dissecting aneurysm of the pulmonary trunk in a beluga whale (Delphinapterus leucas)
6. Levels of organochlorine chemicals in tissues of beluga whales (Delphinapterus leucas) from the St Lawrence Estuary, Quebec, Canada
7. Pathology of stranded beluga whales (Delphinapterus leucas) from the St Lawrence Estuary, Quebec
8. Organochlorine contaminants in belugas, Delphinapterus leucas, from Canadian waters
9. Aromatic DNA-carcinogen adducts in beluga whales (Delphinapterus leucas) from the Canadian arctic and the Gulf of St Lawrence
10. Heavy metals and selenium in tissues of beluga whales, Delphinapterus leucas, from the Canadian Arctic and the St Lawrence estuary
11. Classification of P-450 monooxygenase activities in beluga (Delphinapterus leucas) from patterns of PCB, PCDD and PCDF accumulation
12. A spontaneous outbreak of polychlorinated biphenyl (PCB) toxicity in Rhesus monkeys (Macaca mulatta): toxicopathology
13. Polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs): biochemistry, toxicology, and mechanism of action
14. Toxic Chemicals in the Great Lakes and Associated Effects, Environment Canada, Fisheries and Oceans Canada, Health and Welfare Canada
15. Seasonal, geographical and size-induced variability in mercury content of Mytilus edulis in an estuarine environment: a reassessment of mercury pollution level in the Estuary and Gulf of St Lawrence
16. Distinction between American eels (Anguilla rostrata) of different geographic origins on the basis of their organochlorine contaminant levels
17. Geochronology for mercury pollution in the sediments of the Saguenay fjord, Quebec
18. Polycyclic aromatic hydrocarbons in sediments from the Saguenay fjord, Canada
19. Niveau de contamination par le mercure des sediments de surface et des crevettes du fjord du Saguenay en 1985–1986
20. Introductory note
21. Biology of White Whales (Delphinapterus leucas) in Western Hudson Bay
22. The beluga (Delphinapterus leucas); growth at age based on a captive specimen and a discussion of factors affecting natural mortality estimates
23. A Gel-Permeation/Column Chromatography Cleanup Method for the Determination of CDDs in Animal Tissue
24. Comparison of PCB quantitation methods: re-analysis of archived specimens of herring gull eggs from the Great Lakes
25. Développement d'une méthode d'évaluation de l'impact des HAP sur les organismes aquatiques
26. Dosimetry of PAH skin carcinogenesis: covalent binding of benzo(a)pyrene to mouse epidermal DNA
27. Distribution estivale du béluga du Saint-Laurent; synthèse 1986 à 1992
28. Photographic Census Surveys of the St. Lawrence Population, 1988 and 1990
29. Distribution annuelle et caractérisation préliminaire des habitats du béluga, Delphinapterus leucas, du Saint-Laurent
30. The Occurrence of Tumors in Domestic Animals
31. Tumors in St. Lawrence Beluga Whales (Delphinapterus leucas)
32. PHENOXY AND PICOLINIC ACID HERBICIDES AND SMALL-INTESTINAL ADENOCARCINOMA IN SHEEP
33. Toxic compounds and health and reproductive effects in St. Lawrence beluga whales
34. In vivo covalent binding of organic chemicals to DNA as a quantitative indicator of chemical carcinogenisis
35. Immunosuppressive activities of polychlorinated dibenzofuran congeners: quantitative structure-activity relationship and interactive effects
36. 2,3,7,8,-tetrachlorodibenzo-p-dioxin and related halogenated hydrocarbons: examination of the mechanism of toxicity
37. Effects of polychlorinated biphenyls with Ah receptor affinity on lymphoid development in the thymus and the bursa of Fabricius of chick embryos in ovo
38. Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in C57BI/6 mice congenic at the Ah locus
39. Evaluation of the immunotoxicity of low level PCB exposure in the rat
40. Effect of lead, polychlorinated biphenyls and cyclophosphamide in rat natural killer cells, interleukin 2, and antibody synthesis
41. Immunotoxicity studies of PCB (Aroclor 1254) in the adult Rhesus (Macaca mulatta) monkey — preliminary report
42. Polychlorinated biphenyl and hexachlorobenzene induced humoral immunosuppression
43. Effect of polychlorinated biphenyls on the immune response of rhesus monkeys and mice
44. Environmental chemical-induced immune dysfunction
45. Clinical and experimental studies on impairment of respiratory organs in chlorobiphenyl poisoning
46. Function of adrenal gland zona fasciculata in rats receiving polychlorinated biphenyls
47. 3,4,3′,4′-tetrachlorobiphenyl distribution and induced effects in the rat adrenal gland. Localization in the zona fasciculata
48. Toxicological assessment of chlorinated diphenyl ethers in the rat
49. Effect of polychlorinated biphenyl on viral infections in mice
50. Biphenyl-exposed rabbits
51. Polychlorinated biphenyl: interaction with duck hepatitis virus
52. Enhanced polychlorinated biphenyl lesions in Moloney leukemia virus-infected mice
53. Suppression of MHV-3-activated macrophages by dieldrin
54. Modulation of serum complement levels following exposure to polychlorinated dibenzo-p-dioxins
55. Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean
56. The immunology of marine mammals
57. Comparison of body weights, organ weights and histological features of selected organs of gnotobiotic, conventional and isolator-reared contaminated pigs
58. Some histological and functional aspects of lymphoid tissue in germfree animals
59. Mass mortality of harbor seals: pneumonia associated with influenza A virus
60. Histopathologic and immunocytochemical studies of distemper in harbor porpoises
61. Pathologic and immunocytochemical studies of morbillivirus infection in striped dolphins (Stenella coeruleoalba)
62. Morbillivirus in dolphins
63. Epizootiology of marine mammal morbilliviruses in the western north Atlantic
64. Simplification in the etiology of recent seal deaths
65. The committee on the status of endangered wildlife in Canada (COSEWIC): history and progress
66. The cheetah is depauperate in genetic variation
67. Genetic basis for species vulnerability in the cheetah
68. DNA variation of the mammalian major histocompatibility complex reflects genomic diversity and population history
69. Genetic variation of the St. Lawrence beluga whale population assessed by DNA fingerprinting
70. Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index
71. Enumeration of 6-thioguanine-resistant T-lymphocytes in the peripheral blood of nonhuman primates (Cynomolgus monkeys)
72. Molecular analyses of in vivo hprt mutations in human T-lymphocytes. III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins
73. Studies of DNA alterations in in vivo somatic cell mutations in humans
74. hprt mutations in vivo in human T-lymphocytes: frequencies, spectra and clonality
75. 6-Thioguanine-resistant T-lymphocyte autoradiographic assay. Determination of variation frequencies in individuals suspected of radiation exposure
76. In vitro induction, expression and selection of thioguanine-resistant mutants with human T-lymphocytes
77. A flow cytometric comparison of DNA content and glutathione levels in hepatocytes of English sole (Parophyrs vetulus) from areas of differing water quality
78. From gene to carcinogen: a rapidly evolving field in molecular epidemiology
79. Epidemiologic approaches to assessing human cancer risk from consuming aquatic food resources from chemically contaminated water
80. Practical causal inference for ecoepidemiologists
81. Multiple endpoints for somatic mutations in humans provide complementary views for biodosimetry, genotoxicity and health risks
82. Adenocarcinoma of the salivary gland in a beluga whale (Delphinapterus leucas)
83. Occurrence of tumors in domestic animals. Data from 12 United States and Canadian colleges of veterinary medicine
84. Adenocarcinoma of the jejunum in two cows
85. Carcinoma of the small intestine of sheep in Iceland. A pathological and epizootiological study