Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators

Molecular and Cellular Biology

Volumn 14, Issue 8, 1994, Pages 5259-5267

  Rao, Sunkara S ^a   Chu, Caryn ^a   Kohtz, D Stave ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; PROTEIN KINASE C;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; MYOBLAST; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; REPORTER GENE; SKELETAL MUSCLE;

EID: 0028145332     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.14.8.5259     Document Type: Article

References (74)

1. 1 phase in primary human T lymphocytes. J. Biol. Chem. 267:4113-4119.
2. Bader, D., T. Masaki, and D. Fischman. 1982. Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J. Cell Biol. 95:763-770.
3. 1. Genes Dev. 7:812-821.
4. Benezra, R., R. Davis, D. Lockshon, D. Turner, and H. Weintraub. 1990. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61:49-59.
5. Bengal, E., L. Ransone, R. Scharfman, V. Dwarki, S. Tapscott, H. Weintraub, and I. Verma. 1992. Functional antagonism between c-jun and myoD proteins: a direct physical association. Cell 68:507-519.
6. Blau, H., C.-P. Chiu, and C. Webster. 1983. Cytoplasmic activation of human nuclear genes in stable heterokaryons. Cell 32:1171-1180.
7. Braun, T., E. Bober, G. Buschhausen-Denker, E. Tannisch, and H. Arnold. 1989. A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion to 10T1/2 fibroblasts. EMBO J. 8:701-709.
8. Braun, T., E. Bober, B. Winter, N. Rosenthal, and H. Arnold. 1990. Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 11. EMBO J. 9:821-831.
9. Brennan, T., D. Edmondson, L. Li, and E. Olson. 1991. Transforming growth factor β represses the actions of myogenin through a mechanism independent of DNA binding. Proc. Natl. Acad. Sci. USA 88:3822-3826.
10. Buskin, J. N., and S. D. Hauschka. 1989. Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene. Mol. Cell. Biol. 9:2627-2640.
11. 1 phase and is repressed by fibroblast growth factor. J. Cell Biol. 105:949-956.
12. Cocks, B., G. Vairo, S. Bodrug, and J. Hamilton. 1992. Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents. J. Biol. Chem. 267:12307-12310.
13. Cole, F., T. Fasy, S. Rao, M. DePeralta, and D. Kohtz. 1993. Growth factors that repress myoblast differentiation sustain phosphorylation of a specific site on histone H1. J. Biol. Chem. 268:1580-1588.
14. Crescenzi, M., T. Fleming, A. Lassar, H. Weintraub, and S. Aaronson. 1990. MyoD induces growth arrest independently of differentiation in normal and transformed cells. Proc. Natl. Acad. Sci. USA 87:8442-8446.
15. Davis, R., H. Weintraub, and A. Lassar. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51:987-1000.
16. Dowdy, S., P. Hinds, K. Louie, S. Reed, A. Arnold, and R. Weinberg. 1993. Physical interaction of the retinoblastoma protein with human D cyclins. Cell 73:499-511.
17. Ewen, M., H. Sluss, C. Sherr, H. Matsushime, J. Kato, and D. Livingston. 1993. Functional interactions of retinoblastoma protein with mammalian D-type cyclins.. Cell 73:487-497.
18. 1 phase of the cell cycle. Cell 67:293-303.
19. German, C., G. Merlino, M. Willingham, I. Pastan, and B. Howard. 1982. The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. USA 79: 6777-6781.
20. Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
21. Gu, W., J. Schneider, G. Condorelli, S. Kaushal, V. Mahdavi, and B. Nadal-Ginard. 1993. Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72:309-324.
22. Hartwell, L., and T. Weinert. 1989. Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634.
23. Hinds, P., S. Mittnacht, V. Dulic, A. Arnold, S. Reed, and R. Weinberg. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 71:993-1006.
24. Holloway, S., M. Glotzer, R. King, and A. Murray. 1993. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73:1393-1402.
25. Hu, J.-S., E. N. Olson, and R. E. Kingston. 1992. HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors. Mol. Cell. Biol. 12:1031-1042.
26. Inaba, T., H. Matsushime, M. Valentine, M. Roussel, C. Sherr, and A. Look. 1992. Genomic organization, chromosomal localization, and independent expression of human CYL (cyclin D) genes. Genomics 13:565-574.
27. Jaynes, J. B., J. E. Johnson, J. N. Buskin, C. L. Gartside, and S. D. Hauschka. 1988. The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer. Mol. Cell. Biol. 8:62-70.
28. Jen, Y., H. Weintraub, and R. Benezra. 1992. Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins. Genes Dev. 6:1466-1479.
29. Kato, J., H. Matsushime, S. Hiebert, M. Ewen, and C. Sherr. 1993. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev. 7:331-342.
30. 1 cyclins D2 and D3 but not D1. Proc. Natl. Acad. Sci. USA 90:11513-11517.
31. Kim, S., K. Kim, S. Tapscott, T. Winokur, K. Park, H. Fujika, H. Weintraub, and A. Roberts. 1992. Inhibition of protein phosphatases blocks myogenesis by first altering MyoD binding activity. J. Biol. Chem. 267:15140-15145.
32. Koppe, R., P. Hallauer, G. Karpati, and K. Hastings. 1989. cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs. J. Biol. Chem. 264:14237-14333.
33. Lassar, A., R. Davis, W. Wright, T. Kadesch, C. Murre, A. Voronova, D. Baltimore, and H. Weintraub. 1991. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo. Cell 66:305-315.
34. 1 phase of the cell cycle. J. Cell Biol. 103:1799-1805.
35. 1 cyclin (Cln) function in yeast. Cell 66:1197-1206.
36. Li, L., J.-C. Chambard, M. Karin, and E. Olson. 1992. fos and jun repress transcriptional activation by myogenin and MyoD: the amino terminus of jun can mediate repression. Genes Dev. 6:676-689.
37. Li, L., J. Zhou, G. James, R. Heller-Harrison, M. Czech, and E. Olson. 1992. FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains. Cell 71:1181-1194.
38. Marshall, C. 1991. Tumor suppressor genes. Cell 64:313-326.
39. Massague, J., S. Cheipetz, T. Endo, and B. Nadal-Ginard. 1986. Type β transforming growth factor is an inhibitor of myogenic differentiation. Proc. Natl. Acad. Sci. USA 83:8206-8210.
40. 1 cyclins. Cell 71:323-334.
41. 1. Cold Spring Harbor Symp. Quant. Biol. 56:69-74.
42. 1 phase of the cell cycle. Cell 65:701-813.
43. Miner, J., and B. Wold. 1990. Herculin, a fourth member of the MyoD family of myogenic regulatory genes. Proc. Natl. Acad. Sci. USA 87:1089-1093.
44. Minshull, J., R. Golsteyn, C. Hill, and T. Hunt. 1990. The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J. 9:2865-2875.
45. Motokura, T., T. Bloom, H. Kim, H. Juppner, J. Ruderman, H. Kronenberg, and A. Arnold. 1991. A novel cyclin encoded by a bcl 1-linked candidate oncogene. Nature (London) 350:512-515.
46. Mueller, P., and B. Wold. 1989. In vivo footprinting of a musclespecific enhancer by ligation mediated PCR. Science 246:780-786.
47. Neuhold, L., and B. Wold. 1993. HLH forced dimers: tethering MyoD to E47 generates a dominant positive myogenic factor insulated from negative regulation by Id. Cell 74:1033-1042.
48. Norbury, C., and P. Nurse. 1992. Animal cell cycles and their control. Annu. Rev. Biochem. 61:441-470.
49. Nurse, P. 1990. Universal control mechanism regulating cell cycle timing of M-phase. Nature (London) 344:503-508.
50. Olson, E. 1992. Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol. 154:261-272.
51. Olson, E., E. Steinberg, J. Hu, G. Spizz, and C. Wilcox. 1986. Regulation of myogenic differentiation by type β transforming growth factor. J. Cell Biol. 103:1799-1805.
52. Piechaczyk, M., J. Blanchard, L. Marty, C. Dani, F. Panabieres, S. Sabouty, P. Fort, and P. Jeanteur. 1984. Post-transcriptional regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression in rat tissues. Nucleic Acids Res. 12:6951-6963.
53. cdc2. Cell 58:833-846.
54. Pines, J., and T. Hunter. 1990. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (London) 346:760-763.
55. Quelle, D., R. Ashmun, S. Shurtleff, J. Kato, D. Bar-Sagi, M. Roussel, and C. Sherr. 1993. Overexpression of mouse D-type cyclins accelerates G, phase in rodent fibroblasts. Genes Dev. 7:1559-1571.
56. Rao, S., and D. Kohtz. Positive and negative regulation of D-type cyclins by bFGF and TGF-β. Submitted for publication.
57. Rhodes, S., and S. Koniecszny. 1989. Identification of MRF4: a new member of the muscle regulatory gene family. Genes Dev. 3:2050-2061.
58. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
59. Sartorelli, V., K. Webster, and L. Kedes. 1990. Muscle-specific expression of the cardiac α-actin gene requires MyoD1, CArG-box binding factors, and Sp1. Genes Dev. 4:1811-1822.
60. 1 cyclins. Cell 73:1059-1065.
61. Sorrentino, V., R. Pepperkok, R. Davis, W. Ansorge, and L. Philipson. 1990. Cell proliferation inhibited by MyoD1 independently of myogenic differentiation. Nature (London) 345:813-815.
62. Spizz, G., D. Roman, A. Strauss, and E. Olson. 1986. Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of proliferation. J. Biol. Chem. 261:9483-9488.
63. Walker, D., and J. Mailer. 1991. Role for cyclin A in the dependence of mitosis on completion of DNA replication. Nature (London) 354:314-317.
64. Weinberg, R. 1991. Tumor suppressor genes. Science 254:1138-1146.
65. Weintraub, H., R. Davis, D. Lockshon, and A. Lassar. 1990. MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. Proc. Natl. Acad. Sci. USA 87:5623-5627.
66. Weintraub, H., R. Davis, S. Tapscott, M. Thayer, M. Krause, R. Benezra, T. Blackwell, D. Turner, R. Rupp, S. Hollenberg, Y. Zhuang, and A. Lassar. 1991. The MyoD gene family: nodal point during specification of the muscle cell lineage. Science 251:761-765.
67. Weintraub, H., V. Dwarki, I. Verma, R. Davis, S. Hollenberg, L. Snider, A. Lassar, and S. Tapscott. 1991. Muscle-specific transcriptional activation by MyoD. Genes Dev. 5:1377-1386.
68. Weintraub, H., S. Tapscott, R. Davis, M. Thayer, M. Adam, A. Lassar, and A. Miller. 1989. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc. Natl. Acad. Sci. USA 86:5434-5438.
69. Wentworth, B., M. Donoghue, J. Engert, E. Berglund, and N. Rosenthal. 1991. Paired MyoD-binding sites regulate myosin light chain gene expression. Proc. Natl. Acad. Sci. USA 88:1242-1246.
70. Won, K., Y. Xiong, D. Beach, and M. Gilman. 1992. Growthregulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. USA 89:9910-9914.
71. Wright, W., D. Sassoon, and V. Lin. 1989. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD1. Cell 56:607-617.
72. Xiong, Y., T. Connolly, B. Futcher, and D. Beach. 1991. Human D-type cyclins. Cell 65:691-699.
73. Xiong, Y., H. Zhang, and D. Beach. 1992. D type cyclins associate with multiple protein kinases and the DNA and replication repair factor PCNA. Cell 71:505-514.
74. Xiong, Y., H. Zhang, and D. Beach. 1993. Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 7:1571-1583.