Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII

Journal of Biological Chemistry

Volumn 269, Issue 41, 1994, Pages 25699-25709

  Seger, R ^a   Seger, D ^a   Reszka, A A ^a   Munar, E S ^a   Eldar Finkelman, H ^a   Dobrowolska, G ^a   Jensen, A M ^a   Campbell, J S ^a   Fischer, E H ^a   Krebs, E G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL PROLIFERATION; CELL SPECIFICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; MITOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL TRANSPORT; CELL COMPARTMENTATION; CELL DIVISION; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION;

EID: 0028143002     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)