T cell epitope recognition involved in the low-responsiveness to a region of hen egg lysozyme (46-61) in C57BL/6 mice

Molecular Immunology

Volumn 31, Issue 11, 1994, Pages 803-812

  Jang, Yong Suk ^a   Mikszta, John A ^a   Kim, Byung S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

antigen processing; hen egg lysozyme; low responder mice; phosphorylcholine conjugation; T cell epitope

Indexed keywords

EPITOPE; IA ANTIGEN; LYSOZYME; PHOSPHORYLCHOLINE; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; HYBRIDOMA; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMAL; ANTIGEN-PRESENTING CELLS; CHICKENS; EGG PROTEINS; EPITOPES; HYBRIDOMAS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MURAMIDASE; PEPTIDE FRAGMENTS; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES;

ANIMALIA;

EID: 0028142784     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(94)90018-3     Document Type: Article

References (49)

1. Mechanisms influencing the immunodominance of T cell determinants
2. k molecule
3. T-cell recognition of lysozyme: the biochemical basis of presentaion
4. Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope
5. Functional analysis of the interaction of the antigen-specific T cell receptor with its ligands
6. Binding of immunogenic peptides to Ia histocompatibility molecules
7. Molecular mapping of a histocompatibility-restricted immunodominant T cell epitope with synthetic and natural peptides: Implications for T cell antigenic structure
8. T-cell recognition of proteins: conclusions from the localization of the full T-cell recognition profiles of two native proteins
9. Influences of antigen processing on the expression of the T cell repertoire: evidence for MHC-specific hindering structures on the products of processing
10. Interaction between a “processed” ovabulmin peptide and Ia molecules
11. Autologous peptides constitutively occupy the antigen binding site on Ia
12. Affinity labeling of a phosphorylcholine binding mouse myeloma protein
13. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
14. Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme
15. Different roles for thiol and aspartyl proteases in antigen presentation of ovalbumin
16. H-2 compatibility is required for T-cell-mediated lysis of target cells injected with lymphocytic choriomeningitis virus
17. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
18. The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site
19. T cell determinant structure: cores and determinant envelopes in three mouse major histocompatibility complex haplotypes
20. 2-terminal domain of the class II major histocompatibility polypeptide Aβ
21. Long term culture of tumor-specific cytotoxic T cells
22. Mechanisms of antigen processing
23. Effects of pH and polysaccharides on peptide binding to class II major histocompatibility molecules
24. Multiple H-2 and non-H-2 genes controlling the anti-lysozyme response: alternative gene constellations can lead to responsiveness
25. Analysis of the T cell reactivities to phosphorylcholine-conjugated hen egg lysozyme in C57BL/6 mice: hapten-conjugate specificity reflects an altered expression of a major carrier epitope
26. Identification of self-peptides bound to purified HLA-B27
27. Enhanced binding of peptide antigen to purified class II major histocompatibility complex molecules at acidic pH
28. Antigen-inducibile, H-2 restricted, interleukin-2-producing T cell hybridomas
29. Constraints in antigen processing result in unresponsiveness to a T cell epitope of hen egg lysozyme in C57BL/6 mice
30. The molecular basis of the requirement for antigen processing of pigeon cytochrome c prior to T cell activation
31. Binding of photoreactive lysozyme peptides to murine histocompatibility class II molecules
32. The structure of HLA-B27 reveals nonamer selfpeptides bound to an extended conformation
33. Mechanisms of idiotype suppression. III. Relative resistance of PBA-induced antiphosphorylcholine responses to in vitro idiotype suppression
34. k
35. Genetic control of the immune response to hen egg white lysozyme in mice. I. Antibody and T-lymphocyte proliferative responses to the native protein
36. bm12 mutation using site-directed mutagenesis and DNA-mediated gene transfer
37. Sequence analysis of peptides bound to MHC class II molecules
38. Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs
39. Relative contribution of “determinant selection” and “holes in the T-cell repertoire” to T-cell responses
40. Immune response (Ir) genes of the murine major histocompatibility complex
41. Analysis of lysozyme-specific immune response by synthetic peptides. I. Characterization of antibody and T cell-mediated responses to the N-terminal peptide of hen egg-white lysozyme
42. Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells
43. A cell-free model system for the study of antigen processing
44. Identification of proteases that process distinct epitopes on the same protein
45. Nature of the antigenic complex recognized by T lymphocytes. IV. Inhibition of antigen-specific T cells proliferation by antibodies to similar macrophage Ia antigen
46. Fine specificity of genetic regulation of guinea pig T lymphocyte and responses to angiotensin II and related peptides
47. Antigen recognition by class-I-restricted T lymphocytes
48. d molecule
49. The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes