Optical mapping of repolarization and refractoriness from intact hearts

Circulation

Volumn 90, Issue 3, 1994, Pages 1469-1480

  Efimov, Igor R ^a   Huang, David T ^a   Rendt, James M ^a   Salama, Guy ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

action potentials; electrophysiology; mapping

Indexed keywords

CALCIUM CHANNEL; FLUORESCENT DYE; POTASSIUM CHANNEL; SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; COMPUTER SIMULATION; FEMALE; FLUORESCENCE; GUINEA PIG; HEART CYCLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE POTENTIAL; HEART MUSCLE REFRACTORY PERIOD; HEART REPOLARIZATION; HYPOXIA; LIGHT EMITTING DIODE; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL;

EID: 0028142769     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.90.3.1469     Document Type: Article

References (21)

1. Moe GK, Rheinboldt WC, Abildskov JA. A computer model of atrial fibrillation. Am Heart J. 1964;67:200-220.
2. Reshetilov AV, Pertsov AM, Krinsky VI. Myocardial parameters controlling vulnerability: analysis of mathematical models [in Russian]. Biofizika. 1979;24:129-134.
3. Hoffman BF, Kao CY, Suckling EE. Refractoriness in cardiac muscle. Am J Physiol. 1957;190:473-482.
4. Gough WB, Mehra R, Restivo M, Zeiler RH, El-Sherif N. Reentrant ventricular arrhythmias in the late myocardial infarction period in the dog, 13: correlation of activation and refractory maps. Circ Res. 1985;57:432-442.
5. Michelson EL, Spear JF, Moore EN. Electrophysiological and anatomical correlates of sustained ventricular tachyarrhythmias in a model of chronic myocardial infarction. Am J Cardiol. 1980;45: 583-590.
6. Avitall B, Naimi S, Levine HJ. Prolongation of the conduction time of early premature beats: a marker of ventricular action potential duration. Am Heart J. 1988;116:1247-1252.
7. Wyatt RF. Comparison of estimates of activation and recovery times from bipolar and unipolar electrograms to in vivo transmembrane action potential durations. Proc IEEE Eng Med Biol Soc. Piscataway, NJ: Institute of Electrical and Electronic Engineers; 1980:22-25.
8. Millar CK, Kralios FA, Lux RL. Correlation between refractory periods and activation-recovery intervals from electrograms: effects of rate and adrenergic interventions. Circulation. 1985;72: 1372-1379.
9. Steinhaus BM. Estimating cardiac transmembrane activation and recovery times from unipolar and bipolar extracellular electrograms: a simulation study. Circ Res. 1989;64:449-462.
10. Salama G, Lombardi R, Elson J. Maps of action potential and NADH fluorescence in intact working hearts. Am J Physiol. 1987; 252:H384-H394.
11. Salama G, Rosenbaum DS, Kanai T, Cohen RJ, Kaplan DK. Measuring spatial inhomogeneities in action potential duration and repolarization using optical transmembrane potentials. Proc IEEE Eng Med Biol Soc. Piscataway, NJ: Institute of Electrical and Electronic Engineers; 1989;11:222-223.
12. Rosenbaum DS, Kaplan DT, Kanai A, Jackson L, Garan H, Cohen RJ, Salama G. Repolarization inhomogeneities in ventricular myocardium change dynamically with abrupt cycle length shortening. Circulation. 1991;84:1333-1345.
13. Efimov IR, Huang DT, Rendt JM, Salama G. Mapping of refractory periods with voltage-sensitive dyes. Proc IEEE Eng Med Biol Soc. Piscataway, NJ: Institute of Electrical and Electronic Engineers; 1993;15:703-704.
14. Salama G, Kanai A, Efimov IR. Subthreshold stimulation of Purkinje fiber interrupts ventricular tachycardia in intact hearts. Cire Res. 1994;74:604-619.
15. Mitra R, Morad M. A uniform enzymatic method for dissociation of myocytes from hearts and stomachs of vertebrates. Am J Physiol. 1985;249:H1056-H1060.
16. Beeler GW, Reuter H. Reconstruction of action potential of ventricular myocardial fibers. J Physiol. 1977;268:177-210.
17. Lazzara R, El-Sherif N, Scherlag BJ. Disorders of cellular electrophysiology produced by ischemia of the canine His bundle. Circ Res. 1975;36:444-454.
18. Gettes LS, Reuter H. Slow recovery from inactivation of inward currents in mammalian myocardial fibers. J Physiol (Lond). 1974; 240:703-724.
19. Rozanski GJ, Jalife J, Moe GK. Determinants of postrepolarization refractoriness in depressed mammalian ventricular muscle. Circ Res. 1984;55:486-496.
20. Kohlhart M, Krause H, Kubler M, Herdey A. Kinetics of inactivation and recovery of the slow inward current in the mammalian ventricular myocardium. Pflugers Arch. 1974;355:1-17.
21. Dillon MS. Optical recordings in the rabbit heart show that defibrillation strength shocks prolong the duration of depolarization and the refractory period. Circ Res. 1991;69:842-856.