Staurosporine and its derivatives enhance f-Met-Leu-Phe-induced superoxide production via phospholipase D activation in human polymorphonuclear leukocytes

International Journal of Clinical Pharmacology and Therapeutics

Volumn 32, Issue 8, 1994, Pages 422-428

  Mori, T ^a   Ando, M ^a   Takagi, K ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

K252a; Neutrophils; Phospholipase D; Staurosporine; Superoxide production

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; K 252A; NA 332; NA 379; NA 381; NA 382; PHORBOL 12 ACETATE 13 MYRISTATE; PHORBOL ESTER; PHOSPHATIDATE PHOSPHATASE; PHOSPHOLIPASE D; PROPRANOLOL; PROTEIN KINASE C; STAUROSPORINE; STAUROSPORINE DERIVATIVE; SUPEROXIDE; THROMBOCYTE ACTIVATING FACTOR; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; NEUTROPHIL; RESPIRATORY BURST;

ALKALOIDS; AMINO ACID SEQUENCE; CARBAZOLES; CENTRIFUGATION, DENSITY GRADIENT; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME ACTIVATION; HUMAN; MALE; MOLECULAR SEQUENCE DATA; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; PROPRANOLOL; PROTEIN KINASE C; STAUROSPORINE; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 0028142155     PISSN: 01744879     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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