Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus calmette-guérin

Journal of Experimental Medicine

Volumn 180, Issue 4, 1994, Pages 1499-1509

  Molloy, Anthony ^a   Laochumroonvorapong, Pairote ^a   Kaplan, Gilla ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BCG VACCINE; GLIOTOXIN; GUANOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; RECOMBINANT GAMMA INTERFERON;

APOPTOSIS; ARTICLE; BACTERIAL GROWTH; BCG VACCINATION; CELL DEATH; CELL KILLING; CONTROLLED STUDY; DNA DEGRADATION; HOST CELL; HUMAN; HUMAN CELL; MYCOBACTERIUM TUBERCULOSIS; PREVENTION; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; BLOOD BACTERICIDAL ACTIVITY; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DNA; GUANOSINE TRIPHOSPHATE; HUMAN; HYDROGEN PEROXIDE; MONOCYTES; MYCOBACTERIUM BOVIS; NECROSIS; SUPPORT, U.S. GOV'T, P.H.S.; VACUOLES;

EID: 0028136987     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.180.4.1499     Document Type: Article

References (49)

1. Bloom, B.R., and C.J.L. Murray, 1992. Tuberculosis: commentary on a reemergent killer. Science (Wish. DC). 257:1055.
2. Frieden, T.R., T. Sterling, A. Pablos-Mendez, J.O. Kilburn, G.M. Cauthen, and S.W. Dooley. 1992. The emergence of drug-resistant tuberculosis in New York City. N. Engl. J. Med. 328:521.
3. Vital Statistics: Health Medical Care Government publications. The death rate, for selected causes: 1900-1970. Series B. 149-166.
4. McMurray, D.N., and E.A. Yetley. 1982. Cell-mediated immunity in malnourished guinea pigs after Mycobacterium bovis BCG vaccination. Infect. Immun. 39:755.
5. Lurie, M.R 1930. Route of infection in naturally acquired tuberculosis in the guinea pig. J. Exp Med. 51:769.
6. Mackaness, G.B. 1968. The immunology of antituberculous immunity. Am. Rev. Resp Dis. 97:337.
7. Pierce, C.H., R.J. Dubos, and W.R Schaeffer. 1953. Multiplication and survival of tubercle bacilli in the organs of mice. J. Exp Med. 97:189.
8. North, R.J., and A. Izzo. 1993. Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity. J. Exp Med. 177:1723.
9. Kawamura, I., H. Tsukada, H. Yoshikawa, M. Fujita, K. Nomoto, and M. Mitsuyama. 1992. Gamma interferon-producing ability as a possible marker for protective T-cells against Mycobacterium bovis BCG in mice. J. Immunol. 148:2887.
10. Kaufmann, S.H.E. 1993. Immunity to intracellular bacteria. Annu. Rev. Immunol. 11:129.
11. Rook, G.A.W., J. Steele, L. Fraher, S. Barker, R. Karmali, J. O’riordan, and J. Stanford. 1986. Vitamin D3, gamma interferon and control of proliferation of Mycobacterium tuberculosis. Immunology. 57:159.
12. Douvas, G.S., D.L. Looker, A.E. Vatter, and A.J. Crowle. 1985. Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria. Inject. Immun. 50:1.
13. Canetti, G. 1955. The tubercle bacillus in the pulmonary tuberculous lesion. The tubercle bacillus in the pre-exudative stage. In The Tubercle Bacillus. Springer Publishing Company, New York.
14. Adams, D.O.1976. The granulomatous inflammatory response. A review. Am. J. Pathol. 84:161.
15. Sunderam, G., R.J. McDonald, T. Maniatis, J. Oleska, R. Kapilla, and L. Reichman. 1986. Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS). J. Am. Med. Assoc. 256:362.
16. Williams, G.T., C.A. Smith, N.J. McCarthy, and E.A. Grimes. 1992. Apoptosis: final control point in cell biology. Trends Cell Biol. 2:263.
17. Vaux, D.L. 1993. Toward an understanding of the molecular mechanisms of physiological cell death. Proc. Natl. Acad. Sci. USA. 90:786.
18. Young, J.D.-E. 1989. Killing of target cells by lymphocytes: a mechanistic review. Physiol. Rev. 69:250.
19. Lennon, S.V., S.J. Martin, and T.G. Cotter. 1991. Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Proliferation. 24:203.
20. Cohen, J.J., and R.C. Duke. 1992. Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol. 10:267.
21. Wyllie, A.H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous nuclease activation. Nature (Lonl). 284:555.
22. Laster, S.M., J.G. Wood, and L.R. Gooding. 1988. Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis. J. Immunol. 141:2629.
23. Zheng, L.M., A. Zychlinsky, C.-C. Liu, D.M. Ojcius, and J.D.-E. Young. 1991. Extracellular ATP as a trigger for apoptosis or programmed cell death. J. Cell Biol. 112:279.
24. Duke, R.C., J.J. Cohen, and R. Chervenak. 1986. Differences in target cell DNA fragmentation induced by mouse cytotoxic T-lymphocytes and natural killer cells. J. Immunol. 146:393.
25. Cree, I. A., S. Nurbai, G. Milne, and J. Swanson Beck. 1987. Cell death in granulomata: the role of apoptosis. J. Clin. Pathol. (Lond). 40:1314.
26. Molloy, A., P.A. Meyn, K.D. Smith, and G. Kaplan. 1993. Recognition and destruction of Bacillus Calmette-Guerin-infected human monocytes. J. Exp. Mel 177:1691.
27. Boyum, A. 1968. Separation of leukocytes. Scand.J. Clin. Invest. 21 (Suppl. 97):77.
28. McDonough, K.A., Y. Kress, and B.R. Bloom. 1993. Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect. Immun. 61:2763.
29. Myrvik, Q.N., E.S. Leake, and M.J. Wright. 1984. Disruption of phagosomal membranes of normal alveolar macrophages by the H37Rv strain of Mycobacterium tuberculosis. A correlate of virulence. Am. Rev. Respir. Dis. 129:322.
30. Blanchard, D.K., S. McMillen, and J.Y. Djeu. 1991. IFN-7 enhances sensitivity of human macrophages to extracellular ATP-mediated lysis. J. Immunol. 147:2579.
31. Waring, P., R.D. Eichner, A. Mullbacher, and A. Sjaarda. 1988. Gliotoxin induces apoptosis in macrophages unrelated to its antiphagocytic properties. J. Biol. Chem. 263:18493.
32. Cohen, J.J. 1993. Overview: mechanisms of apoptosis. Immunol Today. 14:126.
33. Zychlinsky, A., M.C. Prevost, and PJ. Sansonetti. 1992. Shigella Jlexneri induces apoptosis in infected macrophages. Nature (Land.). 358:167.
34. Armstrong, J.A., and P. D’arcy Hart. 1971. Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes. J. Exp Med. 134:713.
35. Armstrong, J.A., and P. D’arcy Hart. 1975. Phagosome-lyso-some interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival. J. Exp Med. 142:1.
36. + T-cells of mycobacteria growing in human macrophages. Science (Wash. DC). 260:984.
37. Sturgill-Koszycki, S., H. Schlesinger, P. Chakraborty, P.L. Haddix, H.L. Collins, A.K. Fok, R.D. Allen, S.L. Gluck, J. Heuser, and D.G. Russell. 1994. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science (Wash. DC). 263:678-681.
38. Rook, G.A.W., J. Steele, M. Ainsworth, and B.R. Champion. 1986. Activation of macrophages to inhibit Mycobacterium tuberculosis: comparison of the effects of recombinant gamma interferon on human monocytes and murine peritoneal macrophages. Immunology. 59:333.
39. Gordon, J.L. 1986. Extracellular ATP: effects, sources and fates. Biochem. f. 233:309.
40. Zanovello, P., V. Bronte, A. Rosato, P. Pizzo, and F. Di Vir-gilio. 1990. Response of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell-type dependent lysis and DNA fragmentation, f. Immunol. 145:1545.
41. Clem, R.J., and L.K. Miller. 1993. Apoptosis reduced both the in vitro replication and the in vivo infectivity of a bac-ulovirus. f. Virol. 67:3730.
42. Ravi, E.S., and R.M. Welsh. 1993. Programmed cell death during acute viral infection: a mechanism for virus-induced immune deficiency. J. Virol. 67:5754.
43. White, E. 1993. Regulation of apoptosis by the transforming genes of DNA tumor virus adenovirus. Proc. Soc Exp Biol. Med. 204:30.
44. Portnoy, D.A., R.D. Schreiber, P. Connelly, and L.G. Tilney. 1989. γ-Interferon limits access to Listeria monocytogenes to the macrophage cytoplasm. J. Exp Med. 170:2141.
45. Orme, I.M. 1988. Characteristics and specificity of acquired immunologic memory to M. tuberculosis infection, J. Immunol. 140:3589.
46. Wiegeshaus, E.H., D.N. McMurray, A.A. Grover, G.E. Harding, and D.W. Smith. 1970. Host-parasite relationships in experimental airborne tuberculosis. 3. Relevance of microbial enumeration to acquire resistance in guinea pigs. Am. Rev. Respir. Dis. 102:422.
47. Pelletier, M., A. Forget, D. Bourassa, P. Gros, and E. Skamene. 1982. Immunopathology of BCG infection in genetically resistant and susceptible mouse strains. J. Immunol. 129:2179.
48. + T cell lines. Eur. J. Immunol. 18:59.
49. Flynn, J.-A.L., M.M. Goldstein, K.J. Triebold, B. Roller, and B.R. Bloom. 1992. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA. 89:12013.