Modelling of radiation-induced DNA damage: The early physical and chemical event

International Journal of Radiation Biology

Volumn 66, Issue 5, 1994, Pages 453-457

  Nikjoo, H ^a   O'Neill, P ^b   Terrissol, M ^a   Goodhead, D T ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYL RADICAL;

CHEMISTRY; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; IONIZING RADIATION; MODEL; PRIORITY JOURNAL; RADIATION PHYSICS;

DNA; DNA DAMAGE; HYDROXYL RADICAL; MODELS, GENETIC; MONTE CARLO METHOD; SUPPORT, NON-U.S. GOV'T;

EID: 0028135445     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553009414551451     Document Type: Article

References (16)

1. Rate constants for reactions of radicals in aqueous solution
2. An attempt to model the increase of radiation sensitivity due to the incorporation of cold IUdR or BrdU into DNA of irradiated cells
3. Calculation of initial yields of single- and double-strand breaks in cell nuclei from electrons, protons and alpha particles
4. Early chemical events and initial DNA damage
5. Theoretical investigation of the production of strand breaks in DNA by water radicals
6. Effectiveness of 1·5 keV aluminium K and 0·3 carbon characteristic X-rays at inducing DNA double-strand breaks in yeast cells
7. Biophysical modelling of radiation induced damage in chromosomes
8. The kinetics of radiation-induced strand breakage in polynucleotides in the presence of oxygen: a time-resolved light-scattering study
9. Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution
10. What basis for the development of radiation-induced DNA damage
11. Monte Carlo track structure studies of energy deposition and calculation of initial dsb and RBE
12. Energy deposition in cylindrical volume by monoenergetic electrons 10eV–100keV
13. Primary free radical processes in DNA
14. Estimation of life times and diffusion distances of radicals involved in X-ray induced DNA strand breaks or killing of mammalian cells
15. Mechanism of the radiation-induced degradation of nucleic acids
16. Simulation of space and time evolution of radiolytic species induced by electrons in water