Is trichomonas vaginalis a cause of cervical neoplasia? results from a combined analysis of 24 studies

International Journal of Epidemiology

Volumn 23, Issue 4, 1994, Pages 682-690

  Zhang, Zuo Feng ^a   Begg, Colin B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; DATA ANALYSIS; DATA BASE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MEDICAL INFORMATION; META ANALYSIS; NEOPLASM; PRIORITY JOURNAL; RISK; RISK ASSESSMENT; TRICHOMONAS VAGINALIS; TRICHOMONIASIS; UTERINE CERVIX; UTERINE CERVIX CANCER;

BIOLOGY; CANCER; CASE CONTROL STUDIES; CERVICAL CANCER--ETIOLOGY; COHORT ANALYSIS; DATA ANALYSIS; DISEASES; EPIDEMIOLOGIC METHODS; LITERATURE REVIEW; NEOPLASMS; RISK FACTORS; STUDIES; VAGINAL ABNORMALITIES; VAGINITIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIAS (EPIDEMIOLOGY); CAUSALITY; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX NEOPLASMS; CHILD; COHORT STUDIES; CONFIDENCE INTERVALS; CROSS-SECTIONAL STUDIES; EFFECT MODIFIERS (EPIDEMIOLOGY); FEMALE; HUMAN; INCIDENCE; MIDDLE AGE; ODDS RATIO; POPULATION SURVEILLANCE; PREVALENCE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; SUPPORT, U.S. GOV'T, P.H.S.; TRICHOMONAS VAGINITIS;

EID: 0028131446     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/23.4.682     Document Type: Article

References (67)

1. Schiff man M H. Recent progress in defining the epidemiology of human papillomavirus infection and cervical neoplasia. J Natl Cancer Inst 1992; 84:394-98.
2. Bechtokl E, Reicher N B. The relationship of Trichomonas infestations to false diagnoses of squamous carcinoma of the cervix. Cancer 1952; 5:442-57.
3. Gram IT, Macaluso M, Churchill J, Stalsberg H. Trichomonas vaginalis (TV) and human papillomavirus (HPV) infection and the incidence of cervical intraepithelial neoplasia (CTN) grade III. Cancer Causes Control 1992; 3: 231-36.
4. Mason P R, Gwanzura L. Reduced lymphocyte responses to mitogens in natural and experimental trichomoniasis. Infect Immun 1990; 58: 3553-57.
5. Harington J S. Epidemiology and aetiology of cancer of the uterine cervix, including the detection of carcinogenic N-nitrosamines in the human vaginal vault. S Afr MedJ 1975; 49:443-45.
6. Burgess D E, Knoblock K F, Daugherty T, Robertson N P. Cytotoxin and hemolytic effects of tritrichomonas foetus on mammatinn cells. Infect Immun 1990; 58: 3627-32.
7. siguro T. Gas chromatographic studies on propionic acid, butyric acid and valeric acid in culture fluid of Trichomonas vaginalis. Nippon Sanka Fujinka Gakkai Zasshi 1984; 36: 363-68.
8. Hatten S F Jr., Hughes C P, Reagan J W. An experimental study of the relationship between Trichomonas vaginalis and dysplasia in the uterine cervix. Acta Cytol 1963; 7: 187-90.
9. hakrabarti R N, Dufta K, Sarkhel T, Matty S. Cytologic evidence of the association of different infective lesions with dysplastic changes in the uterine cervix. Eur J Gynaecol Oncol 1992; 13: 398-402.
10. Byrne M A, Parry G C, Morse A, Taylor-Robinson D, Malcolm A D, Coleman D V. A prospective study of human papillomavirus infection of the cervix. Cytopathology 1990; 1: 329-37.
11. O’Farrell N. N-mtrosamines, trichomoniasis and cervical cancer (letter). SAfr MedJ 1989; 75: 247-48.
12. Alberico S, Facca M C, Di Bonito L, Millo R, Casaccia R, Mandruzzato G P. Frequency of cervico-vaginal infections (Trichomonas vaginal is; Chlamydia trachomatis -CH L-; herpes simplex virus -HSV-; human papilloma virus -HPV-) in cervical intraepithelial neoplasia. Eur J Gynaecol Oncol 1988; 9:252-57.
13. Kohan S, Noumoff J, Beckman E M, Morris M, Weiner E, Douglas G W. Colposcopic screening of women with atypical Papanicolaou smears. J Reprod Med 1985; 30: 383-87.
14. Franceschi S, Doll R, Gallwey J, La Vecchia C, Peto R, Spriggs A L. Genital warts and cervical neoplasia: an epidemiological study. Br J Cancer 1983; 48:621-28.
15. Luna G, Hernandez-Perez O, Gallegos G, Rosado A. Uterine cervix cancer. II. Vitamin A and sialic add determination in the vaginal secretion. Arch Invest Med (Mex) 1983; 14: 321-30.
16. Sondheimer S J, Casey M V, Rubin M, Mangan C, Atkinson B, Huggins G R. Mild cervical dysplasia. Experience m a family planning clinic.J Reprod Med 1919;
17. Kessler 1 I. Etiological concepts in cervical carcinogenesis Gynecol Oncol 1981; 12: S7-24.
18. Misra J S, Engineer A D, Tandon P. Cytological studies in women using copper intrauterine devices. Acta Cytol 1977; 21:514-18.
19. Beard C M, Noller K L, O’Fallon W M, Kurland L T, Dockerly M B. Lack of evidence for cancer due to use of metronidazole. N Engl J Med 1979; 301:519-22.
20. Alexander E R. Possible etiologies of cancer of the cervix other than herpesvirus. Cancer Res 1973; 33: 1485-90.
21. Freedman R S, Joosting A C, Ryan J T, Nkoni S. A study of assodated factors, induding genital herpes, in Black women with cervical carcinoma in Johannesburg. SAfr MedJ 1974; 48: 1747-52.
22. Epstein N A. The significance of cellular atypia in the diagnosis of malignancy in ulcers of the female genital tract. Acta Cytol 1972; 16:483-89.
23. Edwards D. Gynaecological abnormalities found at a cytology dink. Br MedJ 1974; 4: 218-21.
24. Vachtel E, Wycherley J, Lee C N. Screening for cancer of the female genital tract in general medical and surgical wards. Practitioner 1972;208:505-08.
25. Singer A. Genital herpes and cervical cancer. Br MedJ 1971; fc 458.
26. Royston I, Aurelian L. The association of genital herpesvirus with cervical atypia and carcinoma in situ. Am J Epidemiol 1970; 91: 531-38.
27. Bertini B, Hornstein M. The epidemiology of trichomoniasis and the role of this infection in the development of carcinoma of the cervix. Acta Cytol 1970; 14:325-32.
28. Meisels A. Dysplasia and carcinoma of the uterine cervix. IV. A correlated cytologic and histologic study with special emphasis on vaginal microbiology Acta Cytol 1969; 13:224-31.
29. Weld G L, Messina A M, Rosenthal E. Comparative quantitative DNA-measurements on Feulgen-stained cervical epithelial cells. Acta Cytol 1966; 10:31-37.
30. Tje Carneri I, Di Re F. Vaginal trichomoniasis and precancerous states of the cervix: a preliminary report. J Obstet Gynaecol Br Commons 1970; 77: 1016-18.
31. Bird G C, Giles P F, Martin J D, Stenhouse N S, Waters E D. A gynaecological cancer survey in a rural community: Busselton, Western Australia. MedJAust 1970; 1:1039-43.
32. Berggrcn O. Association of carcinoma of the uterine cervix and Trichomonas vaginalis infestations. Frequency of Trichomonas vaginalis in prcmvasive and invasive cervical carcinoma. Am J Obstet Gynecol 1969; 105:166-68.
33. Goldberg D M, Hart D M, Waits C. Vaginal fluid ribonuclease activity in the diagnosis of cervical cancer J Obstet Gynaecol Br Com-monw 1968; 75: 762-67.
34. Skrocka M B. Comparison of incondusive smears from gynecological and obstetrical clinics of Johns Hopkins Hospital. J Maine Med Assoc 1967; 58: 79-83.
35. Naguib S M, Lundin F E Jr., Davis H J. Relation of various epidemiology factors to cervical cancer as determined by a screening program. Obstet Gynecol 1966; 28:451-59.
36. Oller L Z Routine exfoliative cytology for cancer and trichomonas detection at a clink for venereal diseases. Br J Verier Dis 1965; 41:304-08.
37. Wingate M B, Comes J S. Carcinoma in situ in a young primigravida. J Obstet Gynaecol Br Commonw 1965; 72: 691-92.
38. Guijon F, Paraskevas M, Rand F, Heywood E, Brunham R, McNicol P. Vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia. Int J Gynaecol Obstet 1992; 37:185-91.
39. Zhang Z F, Graham S, Zielezny M et al. Epidemiology of cervical cancer in a rural Chinese population (Abs.). Am J Epidemiol 1991; 134: 760-61.
40. Koss L G, Wolinska W H. Trichomonas vaginitis cervicitis and its relationship to cervical cancer. Cancer 1959; 12:1171-93.
41. Frost J K. Trichomonas vaginitis and cervical epithelial changes. Ann N Y Acad Sei 1962; 97: 792-99.
42. Simeckova M, Lonser E, Nichols E etal ChronkTrichomoniasis and cervical cancer. Obstet Gynecol 1962; 20:410-12.
43. Thomas D B. An epidemiologic study of carcinoma in situ and squamous dysplasia ofthe uterine cervix. Am J Epidemiol 1973; 98: 10-28.
44. Guijon F B, Paraskevas M, Brunham R. The association of sexual transmitted disease with cervical intraepithelial neoplasia: A case-control study. Am J Obstet Gynecol 1985; 151:185-90.
45. La Vecchia C, Franceschi S, Decarli A et al. Sexual factors, venereal disease, and the risk of intraepithelial and cervical invasive neoplasia. Cancer 1986; 58:935-41.
46. Brinton L A, Hamman R F, Huggins G R etal Sexual and reproductive risk factors for invasive squamous cell cervical cancer. J Natl Cancer Inst 1987; 79:23-30.
47. Slattery M L, Overall J C J, Abbott T M, French T K, Robison L M, Gardner J. Sexual activity, contraception, genital infections, and cervical cancer support for a sexually transmitted disease hypothesis. Am J Epidemiol 1989; 130:248-58.
48. Miller J M, Chambers D C. Infection with Trichomonas vaginitis in a black population. JAMA 1989; 81:701-02.
49. Phat V N, Baviera E, Thevenoo-Gonguet A M, Houissa-Vuong S, Schoonaert M F, Barres D. Aspects cytologiques particulicrs de la trichomonase cervico-vaginale. J Gynecol Obstet Biol Reprod 1983; 13: 143-49.
50. Poulsen HE, Taylor C W (eds). Histological Typing of Female Genital Tract Tumors. Geneva, WHO, 1975.
51. Last J M. A Dictionary of Epidemiology. 2nd edn. New York: Oxford University Press, 1988.
52. Breslow N E, Day N E. Statistical Methods in Cancer Research. Volume I The Analysis of Case-Control Studies. Lyon: IARC scientific Publications No. 32, 1980.
53. Breslow NE, Day NE Statistical Methods in Cancer Research. Volume II The Design and Analysis of Cohort Studies. Lyon: IARC, 1987.
54. Begg C B, Berlin J A. Publication bias: a problem in interpretating medical data. J R Statist Soc Series A 1988; 151:419-63.
55. Begg C B, Mazumdar M. Operating characteristic* of a rank correlation test for publication bias. Biometrics 1994; (in press).
56. Light R J, PÜlemer D B. Summing-up. The Science of Reviewing Research. Cambridge: Harvard University Press, 1984.
57. Olkin I. Reconcilable differences, gleaning insight from conflicting scientific studies. Science 1992; July/AogusL 30-37.
58. Crook T, Wrede D, Tidy J A, Mason W P, Evans D J, Vousden K H. Clonal p53 mutation in primary cervical cancer association with human-papillomavirus-negative tumours. Lancet 1992; 339: 1070-73
59. Wilbanks G D, Turyk M E. Cervical and vulvar neoplasias: Past and present concepts. Serono Symp Pubi Raven 1986; 31:115-32
60. Wilbanks G D, Turyk M E. Danforth 's Obstetrics and Gynecology. New York J B Lippincott Company, 1990
61. Naguib S M, Comstock G W, Davis H J. Epidemiologic study of trichomoniasis in normal women. Obstet Gynecol 1966; 27:60716.
62. Buxton C L, Wemman D, Johnson C. Epidemiology of Trichomonas vaginalis vaginitis a progress report. Obstet Gynecol 1958; 12: 699-702.
63. Stucin M, Bonta S, Kovacic J, Hribar F, Damjanovski L. Circumcision and carcinoma colli uteri in Macedonia, Yugoslavia. Results from a field study. Br J Cancer 1963; 17:400-05.
64. Ter Meuien J, Eberhardt H C, Luande J et al Human papillomavirus (HPV) infection, HIV infection and cervical cancer in Tanzania, East Africa. Int J Cancer 1992; 51: 515-21.
65. Rusüa M, Shubik P. Induction of lung tumors and malignant lymphomas in mice by metronidazole. J Hail Cancer Inst 1972; 48: 721-29.
66. Reitz M, Rumfp M, Knitza R. DNA single strand-breaks in lymphocytes after metronidazole therapy. Arzneim-ForschJDrug Res 1991;41: 155-56.
67. Beard C M, Noller K. L, O’Fallon W M, Kunand L T, Dahlin D C. Cancer after exposure to metronidazole. Mayo Clin Froc 1988; 63: 147-53.