SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

FEBS Letters

Volumn 350, Issue 2-3, 1994, Pages 240-244

  Rinaldi Carmona, Murielle ^a   Barth, Francis ^a   Héaulme, Michel ^a   Shire, David ^a   Calandra, Bernard ^a   Congy, Christian ^a   Martinez, Serge ^a   Maruani, Jeanne ^a   Néliat, Gervais ^b   Caput, Daniel ^a   Ferrara, Pascual ^a   Soubrié, Philippe ^a   Brelière, Jean Claude ^a   Le Fur, Gérard ^a  

^a SANOFI   (France)

^b CEREP

Author keywords

Behavioural responses; cAMP; Cannabinoid receptor; Receptor antagonist

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ADENYLATE CYCLASE; ANANDAMIDE; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; DRUG RECEPTOR; RECEPTOR BLOCKING AGENT; RIMONABANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BINDING KINETICS; BRAIN; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIGAND BINDING; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SMOOTH MUSCLE CONTRACTION; VAS DEFERENS;

ANIMAL; BINDING, COMPETITIVE; BIOLOGICAL ASSAY; BRAIN; CANNABINOIDS; CELL MEMBRANE; CYCLOHEXANOLS; IN VITRO; MICE; MORPHOLINES; NAPHTHALENES; PIPERIDINES; PYRAZOLES; RATS; RECEPTORS, DRUG;

ANIMALIA;

EID: 0028129936     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(94)00773-X     Document Type: Article

References (26)