Inhibition of mammalian hepatic glutathione S-transferases by acetylenic fatty acids

Toxicology Letters

Volumn 73, Issue 2, 1994, Pages 157-165

  Datta, Kaushik ^a   Kulkami, Arun P ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Acetylenic fatty acids; Glutathione S transferase; Inhibition; Lipoxygenase inhibitors

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 CHLORO 4 NITROBENZENE; 5,8,11 ICOSATRIENOIC ACID; ARACHIDONIC ACID; GLUTATHIONE TRANSFERASE; LIPOXYGENASE INHIBITOR; PYRIDINE 1 OXIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; FEMALE; HUMAN; HUMAN TISSUE; ICOSANOID METABOLISM; LIVER CYTOSOL; NONHUMAN; PRIORITY JOURNAL; RAT;

5,8,11,14-EICOSATETRAYNOIC ACID; ANIMAL; FATTY ACIDS, UNSATURATED; FEMALE; GLUTATHIONE TRANSFERASE; HUMAN; IN VITRO; LIVER; RATS;

ANIMALIA; MAMMALIA;

EID: 0028122574     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(94)90105-8     Document Type: Article

References (34)

1. 4 synthetase of rat basophilic leukemia cells
2. Glutathione transferase: structure and catalytic activity
3. 3 with glutathione 5-transferase
4. Antiproliferative effects of lipoxygenase inhibitors on human leukemia cells
5. 2 activation and autoinduction of tumor necrosis factor gene expression by tumor necrosis factor
6. Inhibitors of lipoxygenase have antiproliferative effects on P815 murine mastocytoma cells
7. Inhibition by lipoxygenase inhibitors of 7-bromomethylbenz[a]-anthracene-caused epidermal ornithine decarboxylase induction and skin tumor promotion in mice
8. Eicosapentaenoic acid reduces the invasive and metastatic activities of malignant tumor cells
9. Adjuvant effects of antineoplastic prostaglandins to cisplatin in nude mice bearing human ovarian cancer cells
10. Glutathione transferases and cancer
11. Acetylenic inhibitors of sheep vesicular gland oxygenase
12. The mechanism of inactivation of lipoxygenase by acetylenic fatty acids
13. Inhibition of leukotriene C and leukotriene D biosynthesis
14. Modulation of leukotriene formation by various acetylenic acids
15. Lipoxygenase inhibitors suppress formation of tumor necrosis factor in vitro and in vivo
16. Evidence for identifying fatty acid in rat liver glutathione S-transferase and its possible involvement in the secondary structure
17. Inhibition of hepatic glutathione S-transferase by fatty acids and fatty acid esters
18. Inhibition of human term placental and fetal liver glutathione S-transferase by fatty acids and fatty acid esters
19. Biotransformation of methyl parathion by human foetal liver glutathioneS-transferases: anin vitrostudy
20. A rapid, novel high performance liquid chromatography method for the purification of glutathione S-transferase: an application to the human placental enzyme
21. Glutathione S-transferases
22. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
23. Identification of the fatty acid binding site on glutathione S-transferase P
24. A set of inhibitors for discrimination between the basic isozymes of glutathione transferase in rat liver
25. Depletion of rat hepatic glutathione and inhibition of microsomal trans-2-enoyl-CoA reductase activity following administration of a Dec-2- ynol and Dec-2-ynoic acid
26. Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation
27. Isolation and characterization of the multiple glutathione S-transferases from human liver: evidence for unique heme-binding sites
28. Purification and kinetic mechanism of the major glutathione S-transferase from bovine brain
29. Bovine erythrocyte glutathione S-transferase: purification, inhibition and complex formation
30. 1 (U-60257)
31. Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines
32. Gossypol, a potent inhibitor of arachidonate 5- and 12- lipoxygenases
33. Modulation of resistance to alkylating agents in cancer cell by gossypol enantiomers
34. Leukotriene C synthase in mouse mastocytoma cells