The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen

Blood

Volumn 84, Issue 5, 1994, Pages 1402-1407

  Engel, Pablo ^b   Gribben, John G ^b   Freeman, Gordon J ^b   Zhou, Liang Ji ^b   Nozawa, Yoshihiro ^b   Abe, Masafumi ^b   Nadler, Lee M ^b   Wakasa, Haruki ^b   Tedder, Thomas F ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD86 ANTIGEN; COMPLEMENTARY DNA; EPITOPE; HYBRID PROTEIN; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL PROLIFERATION; CHO CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; SEROLOGY; T LYMPHOCYTE ACTIVATION;

EID: 0028122223     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v84.5.1402.1402     Document Type: Article

References (30)

1. Schwartz RH; Costimulation of T lymphocytes: The role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71:1065, 1992
2. June CH, Ledbetter JA, Linsley PS. Thompson CB: Role of the CD28 receptor in T-cell activation. Immunol Today 11:211, 1990
3. Linsley PS, Clark EA, Ledbetter JA: T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc Natl Acad Sci USA 87:5031, 1990
4. Engel P, Wagner N, Tedder TF: CD80 workshop report, in Schlossman SF, Boumsell L, Gilks W, Harlan J, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd R (eds): Leukocyte Typing V, Oxford, UK, Oxford University, 1994 (in press)
5. Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA: Binding of the B cell activation antigen B7 to CD28 costimilates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med 173:721, 1991
6. Gimmi CD, Freedman GJ, Gribben JG, Sugita K, Freedman AS, Morimoto C, Nadler LM: B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc Natl Acad Sci USA 88:6575, 1991
7. Koulova L, Clark EA, Shu G, Dupont B: The CD28 ligand B7/BB1 provides a costimulatory signal for alloactivation of CD4+ T cells. J Exp Med 173:759, 1991
8. Freeman GJ, Gray GS, Gimmi CD, Lombard DB, Zhou L-J, White M, Fingeroth JD, Gribben JG, Nadler LM: Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J Exp Med 174:625, 1991
9. Chen L, Ashe S, Brady WA, Hellstrom I, Hellstrom KE. Ledbetter JA, McGowan P, Linsley PS: Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71:1093, 1992
10. + T cells by B7-transfected melanoma cells. Science 259:368. 1993
11. Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP: CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356:607, 1992
12. Gimmi CD, Freeman GJ, Gribben JG, Gray G, Nadler LM: Human T cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA 90:6586, 1993
13. Damle NK, Linsley PS, Ledbetter JA: Direct helper T cellinduced B cell differentiation involves interaction between T cell antigen CD28 and B cell activation antigen B7. Eur J Immunol 21:1277, 1991
14. Freedman AS, Freeman G, Horowitz JC, Daley J, Nadler LM: B7, a B cell-restricted antigen that identifies preactivated B cells. J Immunol 139:3260, 1987
15. Nabavi N, Freeman GJ, Gault A, Godfrey D, Nadler LM, Glimcher LH: Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression. Nature 360:266, 1992
16. Freeman GJ, Freedman AS, Segil JM, Lee G, Whitman JF, Nadler LM: B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J Immunol 143:2714, 1989
17. Yokochi T, Holly RD, Clark EA: B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas. J Immunol 128:823, 1982
18. Freedman AS, Freeman GJ, Rhynhart K, Nadler LM: Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol 137:429, 1991
19. Sansom DM, Hall ND: B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro. Eur J Immunol 23:295, 1993
20. Valle A, Yssel GH, Bonnefoy J-Y, Freedman AS, Freeman G, Nadler LM, Banchereau J: mAb 104, a new monoclonal antibody, recognizes the B7 antigen that is expressed on activated B cells and HTL V-1-transformed T cells. Immunology 69:531, 1990
21. Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA: CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 174:561, 1991
22. Freeman GJ, Borriello F, Hodes RJ, Reiser H, Hathcock KS, Laszlo G, McKnight AJ, Kim J, Du L, Lombard DB, Gray GS, Nadler LM, Sharpe AH: Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262:907, 1993
23. Boussiotis VA, Freeman GJ, Gribben JG, Daley J, Gray G, Nadler LM: Activated human B lymphocytes express three CTLA4 counter-receptors which costimulate T cell activation. Proc Natl Acad Sci USA 90:11059, 1993
24. Lenschow DJ, Su GH-T, Zuckerman LA, Nahavi N, Jellis CL, Gray GS, Miller J, Bluestone JA: Expression and functional significance of an additional ligand for CTLA-4. Proc Natl Acad Sci USA 90:11054, 1993
25. Freeman GJ, Gribben JG, Boussiotis VA. Ng JW, Restivo VA, Lombard LA, Gray GS, Nadler LM: Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262:909, 1993
26. Azuma M, Ito D, Yagita H, Okumura K, Phillips JH, Lanier LL, Somoza C: B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366:76, 1993
27. Engel P, Wagner N, Zhou L-J, Tedder TF: CD86 workshop report, in Schlossman SF, Boumsell L, Gilks W, Harlan J, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, Tedder TF, Todd R (eds): Leukocyte Typing V. Oxford. UK, Oxford University. 1994 (in press)
28. Nozawa Y, Wachi E, Tominaga K, Abe M, Wakasa H: A novel monoclonal antibody (FUN-1) identifies an activation antigen in cells of the B-cell lineage and Reed-Sternberg cells. J Pathol 169:309, 1993
29. Tedder TF, Clement LT, Cooper MD: Human lymphocyte differentiation antigens HB-10 and HB-11. I. Ontogeny of antigen expression. J Immunol 134:2983, 1985
30. Hathcock KS, Laszlo G, Dickler HB, Bradshaw J, Linsley P, Hodes RJ: Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science 262:905, 1993