Review article: aspirin and gastrointestinal bleeding

Alimentary Pharmacology & Therapeutics

Volumn 8, Issue 2, 1994, Pages 141-146

  HAWKEY, C J ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; HISTAMINE H2 RECEPTOR ANTAGONIST; INDOMETACIN; MISOPROSTOL; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO;

ANEMIA; GASTROINTESTINAL HEMORRHAGE; HEMOSTASIS; HUMAN; MORBIDITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PROSTAGLANDIN SYNTHESIS; REVIEW; RISK ASSESSMENT; STOMACH EROSION; STOMACH MUCOSA INJURY; STOMACH ULCER;

ANEMIA, HYPOCHROMIC; ANIMAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; GASTRIC MUCOSA; GASTROINTESTINAL HEMORRHAGE; HEMOSTASIS; HUMAN; PEPTIC ULCER HEMORRHAGE;

EID: 0028121456     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.1994.tb00271.x     Document Type: Article

References (53)

1. Gastroscopic observations of the effect of aspirin and certain other substances on the stomach
2. Non‐steroidal, anti‐inflammatory drugs and peptic ulcers
3. Inhibition of prostaglandin synthesis as a mechanism of action of aspirin‐like drugs
4. Separation of aspirin's impairment of haemo‐stasis from mucosal injury in the human stomach
5. Aspirin‐induced gastric mucosal damage
6. Aspirin‐induced ultrastructural change in human gastric mucosa: correlation with potential difference
7. Gastric adaptation occurs with aspirin administration in man
8. Subepithelial haemorrhages and erosions of human stomach
9. Hawkey C J
10. Salicylate‐induced gastrointestinal bleeding: comparison between soluble buffered enteric coated and intravenous administration
11. Nelson R S
12. Aspirin can inhibit gastric mucosal cyclooxygenase without causing lesions in the rat
13. Mechanisms underlying gastric mucosal damage by indomethacin and bile salts, and the action of prostaglandins
14. Gastroduodenal bicarbonate production
15. Allan A, Garner A
16. Effects of 16.16‐dimethyl prostaglandin E2 on surface hydrophobicity of aspirin‐treated canine gastric mucosa
17. Effect of indomethacin on basal and histamine stimulated human gastric acid secretion
18. Effect of ranitidine and indomethacin on nocturnal gastric activity in normal subjects
19. Functional significance of gastric mucosal barrier to sodium
20. Aspirin‐induced changes in gastric function: Role of endogenous prostaglandins and mucosal damage
21. Gastric ulcer, duodenal ulcer and gastric carcinoma: a case‐control study of certain social and environmental factors
22. Aspirin use in patients with major upper gastrointestinal bleeding and peptic ulcer disease
23. Analgesic ingestion and chronic peptic ulcer
24. Peptic ulcer and non‐steroidal anti‐inflammatory agents
25. The effects of chronic aspirin use on duodenal and gastric ulcer hospitalisations
26. Aspirin, paracetamol, and haematemesis and melaena
27. Major upper gastrointestinal tract bleeding
28. Aspirin and bleeding peptic ulcers in the elderly
29. Smoking, nonsteroidal anti‐inflammatory drugs, and acetaminophen in gastric ulcer
30. Variations in the risk of peptic ulcer complications with non‐steroidal antiinflammatory drugs
31. (Randomised double blind controlled trial of intravenous famotidine infusion in 1005 patients with GI bleeding
32. Non‐steroidal anti‐inflammatory drugs and life threatening complications of peptic ulceration
33. Peptic ulcer (PU) deaths
34. Final report on the aspirin component of the ongoing Physicians'Health Study
35. United Kingdom transient ischaemic attack (UK‐TIA) aspirin trial: interim results
36. Randomised trial of prophylactic daily aspirin in British male doctors
37. Risk of upper GI bleeding during TIA prophylaxis with aspirin
38. Drugs and gastric damage
39. A sensitive method for measuring haemoglobin in gastric contents
40. Reduction by enprostil of aspirin induced blood loss from human gastric mucosa
41. Clinicopathological features of non‐steroidal anti‐inflammatory drug‐induced small intestinal structures
42. 51CR excretion in bile
43. Prolongation of intragastric bleeding by acid
44. Does aspirin prolong bleeding from gastric biopsies in man
45. Human gastric mucosal bleeding induced by low dose aspirin, but not warfarin
46. Prevention of NSAID‐induced gastric ulcer with misoprostol: multicentre, double‐blind placebo‐controlled trial
47. Long term effects of misoprostol on gastropathy induced by non‐steroidal anti‐inflammatory drugs (NSAIDs)
48. Prevention of duodenal ulcer in arthritics who are chronic NSAID users: a multicentre trial of the role of misoprostol
49. Prevention of gastroduodenal damage induced by non‐steroidal antiinflammatory drugs: controlled trial on ranitidine
50. Effect of ranitidine on gastroduodenal mucosal damage induced by non‐steroidal anti‐inflammatory drugs
51. Effect of acid and pepsin on blood coagulation and platelet aggregation
52. Aspirin: taken without food to limit gastric mucosal injury and with ranitidine to reduce bleeding