Ifosfamide and Carboplatin Combined with 41.8°C Whole-Body Hyperthermia in Patients with Refractory Sarcoma and Malignant Teratoma

Cancer Research

Volumn 54, Issue 20, 1994, Pages 5346-5350

  Wiedemann, Günter J ^a   Knop, Erdmute ^a   Mentzel, Martin ^a   Geisler, Jürgen ^a   Wagner, Thomas ^a   Eleftheriadis, Sawas ^a   Schmucker, Peter ^a   Klouche, Miriam ^a   Feyerabend, Thomas ^a   Weiss, Christoph ^a   Feddersen, Stephanie ^a   Bucsky, Peter ^b   d'Oleire, Floriane ^c  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; IFOSFAMIDE;

ADOLESCENT; ADULT; ARTICLE; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CARDIOTOXICITY; CLINICAL ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFICACY; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; HYPERTHERMIC THERAPY; MALE; NEPHROTOXICITY; NEUROTOXICITY; PRIORITY JOURNAL; SARCOMA; SCHOOL CHILD; SKIN TOXICITY; TERATOMA; TREATMENT PLANNING;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW; CARBOPLATIN; COMBINED MODALITY THERAPY; FEMALE; HUMANS; HYPERTHERMIA, INDUCED; IFOSFAMIDE; KIDNEY; MALE; MIDDLE AGED; PILOT PROJECTS; SARCOMA; TERATOMA;

EID: 0028113412     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Wiedemann, G.J. Siemens, H.J. Mentzel, M. Biersack, A. Wössmann, W. Knocks, D. Weiss, C. and Wagner, T. Effects of temperature on the therapeutic efficacy and pharmacokinetics of ifosfamide. Cancer Res. 53: 4268-4272, 1993.
2. Wiedemann, G.J. Mella, O. Roszinski, S. Weiss, G. and Wagner, T. Local hyperthermia enhances mitoxantrone cytotoxicity on human derived breast carcinoma and sarcoma xenografts in nude mice. Int. J. Radiat. Oncol. Biol. Phys. 24: 669-673, 1992.
3. Wiedemann, G.J. Roszinski, S. Biersack, A. Weiss, C. and Wagner, T. Local hyperthermia enhances cyclophosphamide, ifosfamide, and cis-diamminedichioro-platinum(II) cytotoxicity on human-derived breast carcinoma and sarcoma xenografts in nude mice. J. Cancer Res. Clin. Oncol. 118: 129-135, 1992.
4. Cohen, J.D. Robins, H.I. and Schmitt, C.L. Tumoricidal interactions of hyperthermia with carboplatin, cisplatin and etoposide in human leukemia cells in vitro. Cancer Lett. 44: 205-210, 1989.
5. Cohen, J.D. and Robins, H.I. Thermal enhancement of tetraplatin and carboplatin in human leukemia cells in vitro. Int. J. Hyperthermia, 6: 1013-1017, 1990.
6. Tapazoglou, E. Cohen, J. Schmitt, C.L. Khatana, A. Sapareto, S.A. and Robins, H.I. Whole body hyperthermia (WBH) and carboplatin: cytotoxicity for murine leukemia and normal bone marrow. Br. J. Cancer, 64: 528-530, 1991.
7. Cohen, J.D. Robins, H.I. and Javid, M. Sensitization of C6 glioma to carboplatin cytotoxicity by hyperthermia and thymidine. J. Neurooncol. 9: 1-8, 1990.
8. Ohno, S. Siddik, Z.H. and Baba, H. Effect of carboplatin combined with whole-body hyperthermia on normal tissue and tumor in rats. Cancer Res. 51: 2994-3000, 1991.
9. Wallner, K.E. DeGregorio, M.W. and Li, G.C. Hyperthermic potentiation cis-diamminedichloroplatinum(II) cytotoxicity in Chinese hamster ovary cells resistant to the drug. Cancer Res. 46: 6242-6245, 1986.
10. Robins, H.I. Cohen, J.D. Schmitt, C.L. Tutsch, I.C.D. Feierabend, C. Arzoomanian, R.Z. Alberti, D. d'Oleire, F. Longo, W. Heiss, C. Rushing, D. Love, R. and Spriggs, D.J. Phase I clinical trial of carboplatin and 41.8°C whole-body hyperthermia in cancer patients. J. Clin. Oncol. 11: 1787-1794, 1993.
11. Robins, H.I. Dennis, W.H. Neville, A.J. Shecterle, L. Martin, P.A. Grossman, J. Davis, T.E. Neville, S. Gillis, W. and Rusey, B.F. A nontoxic system for 41.8°C whole body hyperthermia: results of a Phase I study using a radiant heat device. Cancer Res. 45: 3937-3944, 1985.
12. Van der Zee, J. Van Roon, G.C. Wike-Hooley, J.L. Faithfull, N.S. and Reinhold, H.S. Whole-body hyperthermia in cancer therapy: a report of a phase I-II study. Eur. J. Cancer Clin. Oncol. 19: 1189-1200, 1983.
13. Willnow, U. Lindner, H. Brock, D. Wild, L. Diestelhorst, C. Greiner, C. and Eichstädt, H. Treatment of otherwise incurable malignant tumors in children by hyperthermia and chemotherapy. Dtsch. Med. Wochenschr. 114: 208-213, 1989.
14. Parks, L.C. and Smith, G.V. Systemic hyperthermia by extracorporal induction: techniques and results. In: F.K. Storm (ed.), Hyperthermia in Cancer Therapy, pp. 407-446. Boston: G.K. Hall, 1983.
15. Dahl, O. and Mella, O. Effect of timing and sequence of hyperthermia and cyclophosphamide on a neurogenic rat tumor. Cancer (Phila.), 52: 983-987, 1983.
16. WHO Handbook for Reporting Clinical Trials Data. Geneva: World Health Organization, 1979.
17. Wagner, T. Heydrich, D. Jork, T. Voelcker, G. and Hohorst, H.J. Comparative study on human pharmacokinetics of activated ifosfamide and cyclophosphamide by a modified fluorometric test. J. Cancer Res. Clin. Oncol. 100: 95-104, 1981.
18. Wagner, T. Peter, G. Voelcker, G. and Hohorst, H.J. Characterization and quantitative estimation of activated cyclophosphamide in blood and urine. Cancer Res. 37: 2592-2596, 1977.
19. Kurowski, V. and Wagner, T. Comparative pharmacokinetics of ifosfamide, 4-0H-ifosfamide, chloroacetaldehyde, and 2-and 3-dechloro-ethyl-ifosfamide in patients on fractionated intravenous ifosfamide therapy. Cancer Chemother. Pharmacol. 33: 36-42, 1993.
20. Wagner, T. Mittendorff, F. and Walter, E. Intracavitary chemotherapy with activated cyclophosphamide and simultaneous systemic detoxification with protector thiols in sarcoma 180 ascites tumor. Cancer Res. 46: 2214-2219, 1986.
21. Heinzel, G. Woloszak, R. and Thomann, P. Pharmacokinetics and pharmacodynamic data analysis system for the PC. New York: Gustav Fischer Stuttgart Jena, 1993.
22. d'Oleire, F. Schmitt, C.L. Robins, H.I. Cohen, J.D. and Spriggs D. Cytokine induction in humans by 41.8°C whole-body hyperthermia. J. Natl. Cancer Inst, 85: 833-834, 1993.
23. Ries, F. and Klastersky, J. Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity. Am. J. Kidney Dis. 8: 368-379, 1986.
24. Cooper, B.W. Creger, R.J. Soegiarso, W. Mackay, W.L. and Lazarus, H.M. Renal dysfunction during high-dose cisplatin therapy and autologous hematopoietic stem cell transplantation: effect of aminoglycoside therapy. Am. J. Med. 94: 497-504, 1993.
25. Robins, H.I. Cohen, J.D. and Neville, A.J. Drugs, immunotherapy, and radiotherapy. In: M. Gautherie (ed). Whole Body Hyperthermia: Biological and Clinical Aspects. Berlin: Springer-Verlag, 1992.
26. Robins, H.I. Kalin, N.H. Shelton, S.E. Shecterle, L.M. Barksdale, C.M. Martin, P.A. and Marshall, J. Neuroendocrine changes in patients undergoing whole body hyperthermia. Int. J. Hyperthermia, 3: 99-105, 1987.
27. Motzer, R.J. Niedzwiecki, D. Isaacs, M. Menendez-Botet, G. Tong, W.P. Flombaum, G. Scher, H.I. and Bosl, G.J. Carboplatin-based chemotherapy with pharmacokinetic analysis for patients with hemodialysis-dependent renal insufficiency. Cancer Chemother. Pharmacol. 27: 234-238, 1990.
28. Postmus, P.E. Smit, E.F. Kirkpatrick, A. and Splinter, T.A. Testing the possible non-cross resistance of two equipotent combination chemotherapy regimens against small-cell lung cancer: a phase II study of the EORTC Lung Cancer Cooperative Group. Eur. J. Cancer, 29 A: 204-207, 1993.
29. Green, J.A. and Smith, K. Dose intensity of carboplatin in combination with cyclophosphamide or ifosfamide. Cancer Chemother. Pharmacol. 26: 22-25, 1990.
30. Kuhnle, H. Meerpohl, H.G. Eiermann, W. Roben, S. Lenaz, L. and Achterrath, W. Phase II study of carboplatin/ifosfamide in untreated advanced cervical cancer. Cancer Chemother. Pharmacol. 26: 33-35, 1990.
31. Lotz, J.P. Machover, D. Malassagne, B. Hingh, B. Donsimoni, R. and Gumus, Y. Phase I-II study of two consecutive courses of high-dose ifosfamide and carboplatin with autologous bone marrow transplantation for treatment of adult patients with solid tumors. J. Clin. Oncol. 9: 1860-1870, 1991.