Cyclothiazide unmasks AMPA‐evoked stimulation of [3H]‐L‐glutamate release from rat hippocampal synaptosomes

British Journal of Pharmacology

Volumn 113, Issue 2, 1994, Pages 339-341

  Barnes, Janine M ^a   Dev, Kumlesh K ^a   Henley, Jeremy M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

AMPA; autoreceptors; CNQX; cyclothiazide; glutamate release; GYKI; synaptic plasticity

Indexed keywords

1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; ATROPINE; AUTORECEPTOR; CALCIUM ION; CARBACHOL; CYCLOTHIAZIDE; EXCITATORY AMINO ACID RECEPTOR; GLUTAMIC ACID; POTASSIUM ION; PRESYNAPTIC RECEPTOR; RADIOISOTOPE; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG ANTAGONISM; FEMALE; HIPPOCAMPUS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMAL; BENZOTHIADIAZINES; CARBACHOL; DIURETICS, THIAZIDE; FEMALE; GLUTAMIC ACID; HIPPOCAMPUS; IN VITRO; LONG-TERM POTENTIATION; POTASSIUM; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; STIMULATION, CHEMICAL; SUPPORT, NON-U.S. GOV'T; SYNAPTOSOMES;

EID: 0028109247     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1994.tb16902.x     Document Type: Article

References (9)

1. Molecular characteristics of excitatory amino acid receptors
2. A synaptic model of memory: long‐term potentiation in the hippocampus
3. Excitotoxic cell death
4. 3H]‐norepinephrine release from rat hippocampal slices
5. GYKI 52466, a 2,3‐benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/Kainate receptor responses
6. Muscarinic inhibition of endogenous glutamate release from rat hippocampal synaptosomes
7. Glutamate release from guinea‐pig synaptosomes: stimulation by reuptake‐induced depolarisation
8. Immunochemical characterisation of the non‐NMDA glutamate receptor using subunit specific antibodies
9. A benzodiazepine recognition site associated with the non‐NMDA glutamate receptor