Lipopolysaccharide induces prostaglandin H synthase-2 protein and mRNA in human alveolar macrophages and blood monocytes

Journal of Clinical Investigation

Volumn 93, Issue 1, 1994, Pages 391-396

  Hempel, Stephen L ^a,b   Monick, Martha M ^a   Hunninghake, Gary W ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

prostaglandin synthase; prostaglandins E

Indexed keywords

LIPOPOLYSACCHARIDE; MESSENGER RNA; PROSTAGLANDIN SYNTHASE;

ARTICLE; DNA PROBE; EFFECTOR CELL; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS; SKIN FIBROBLAST;

EID: 0028107128     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116971     Document Type: Article

References (52)

1. 2. Am. Rev. Respir Dis. 135:72-77.
2. Brown, G. P., M. M. Monick, and G. W. Hunninghake. 1988. Human alveolar macrophage arachidonic acid metabolism. Am. J. Physiol. (Cell Physiol. 23). 254:C809-C815.
3. Pueringer, R. J., and G. W. Hunninghake. 1992. Lipopolysaccharide stimulates de novo synthesis of PGH synthese in human alveolar macrophages. Am. J. Physiol. (Lung Cell Mol. Physiol. 6). 262:L78-L85.
4. Rosen, G. D., T. M. Birkenmeier, A. Raz, and M. J. Holtzman. 1989. Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation. Biochem. Biophys. Res. Comm. 164:1358-1365.
5. Kujubu, D. A., B. S. Fletcher, B. C. Varnum, R. W. Lim, and H. R. Herschman. 1991. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem. 266:12866-12872.
6. O'Sullivan, M. G., F. H. Chilton, E. M. Huggins, Jr., and C. E. McCall. 1992. Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase. J. Biol. Chem. 267:14547-14550.
7. Hla, T., and K. Neilson. 1992. Human cyclooxygenase-2 cDNA. Proc. Natl. Acad. Sci. USA. 89:7384-7388.
8. O'Sullivan, M. G., E. M. Huggins, Jr., E. A. Meade, D. L. DeWitt, and C. E. McCall. 1992. Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages. Biochem. Biophys. Res. Comm. 187:1123-1127.
9. Holtzman M. J., J. Turk, and L. P. Shornick. 1992. Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells. J. Biol. Chem. 267:21438-21445.
10. Lee, S. H., E. Soyoola, P. Chanmugam, S. Hart, W. Sun, H. Zhong, S. Liou, D. Simmons, and D. Hwang. 1992. Selective expression of mitogen-inducible cyclooxvgenase in macrophages stimulated with hpopolysaccharide. J. Biol. Chem. 267:25934-25938.
11. Wilborn, J., and M. Peters-Golden. 1992. Differential expression of two distinct cyclooxygenase gene products in rat alveolar and peritoneal macrophages. Clin. Res. 40:722A. (Abstr.)
12. Iwamoto, G. J., M. M. Monick, L. F. Burmeister, and G. W. Hunninghake. 1989. Interleukin 1 release by human alveolar macrophages and blood monocytes. Am. J. Physiol. (Cell Physiol. 25). 256:C1012-C1015.
13. Zavala, D. C., and G. W. Hunninghake. 1983. Lung Lavage. In Recent Advances in Respiratory Medicine. D. C. Glenley and T. L. Petty, editors. Churchill Livingston, Edinburgh, UK. 21-33.
14. Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. J. Clin. Lab. Invest. 21:77-89.
15. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
16. Stinski, M. F., D. R. Thomsen, R. M. Stenberg, and L. C. Goldstein. 1983. Organization and expression of the immediate early genes of human cytomegalovirus. J. Virol. 46:1-14.
17. Lehrach, D., D. Diamond, J. M. Wozney, and H. Boedtkes. 1977. RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry. 16:4743-4751.
18. 2 synthase (cyclooxygenase) in human monocytes. J. Biol. Chem. 265:16737-16740.
19. Aderem, A. A., D. S. Cohen, S. D. Wright, and Z. A. Cohn. 1986. Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites. J. Exp. Med. 164:165-179.
20. Lin, A. H., M. J. Bienkowski, and R. R. Gorman. 1989. Regulation of prostaglandin H synthase mRNA levels and prostaglandin biosynthesis by platelet-derived growth factor. J. Biol. Chem. 264:17379-17383.
21. 2 synthesis in human umbilical vein endothelial cells. J. Biol. Chem. 268:839-844.
22. Nusing, R., and V. Ullrich. 1992. Regulation of cyclooxygenase and thromboxane synthase in human monocytes. Eur. J. Biochem. 206:131-136.
23. Hemler, M. E., and W. E. M. Lands. 1980. Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis. J. Biol. Chem. 255:6253-6261.
24. Shimokawa, T., and W. L. Smith. 1992. Prostaglandin endoperoxide synthase: The aspirin acetylation region. J. Biol. Chem. 267:12387-12392.
25. Smith, W. L. 1992. Prostanoid biosynthesis and mechanisms of action. Am. J. Physiol. (Renal Fluid Electrolyte Physiol. 32). 263:F181-F191.
26. Adams-Brotherton, A. F., and J. C. Hoak. 1983. Prostacyclin biosynthesis in cultured vascular endothelium is limited by deactivation of cyclooxygenase. J. Clin. Invest. 72:1255-1261.
27. Willems, C., P. G. de Groot, G. A. Pool, M. S. Gonsalvez, W. G. Van Aken, and J. A. Van Mounk. 1982. Arachidonate metabolism in cultured human vascular endothelial cells evidence for two prostaglandin synthetic pathways sensitive to acetylsalicylcic acid. Biochem. Biophys. Acta. 713:581-588.
28. Hempel, S. L., D. L. Haycraft, J. C. Hoak, and A. A. Spector. 1990. Reduced prostacyclin formation after reoxygenation of anoxic endothelium. Am. J. Physiol. (Cell Physiol. 28). 259:C738-C745.
29. Barchowsky, A., R. S. Kent, and A. R. Whorton. 1987. Recovery of porcine aortic endothelial cell prostaglandin synthesis following inhibition by sublethal concentrations of hydrogen peroxide. Biochim. Biophys. Acta. 927:372-381.
30. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1973. Culture of human endothelial cells derived from umbilical veins. J. Clin. Invest. 52:2745-2756.
31. Wu. K. K., H. Hatzakis, S. S. Lo, D. C. Seong, and S. K. Sanduja. 1988. Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester. J. Biol. Chem. 263:19043-19047.
32. Tsai, A. L., R. Sanduja, and K. K. Wu. 1990. Evidence for two pools of prostaglandin H synthase in human endothelial cells. In Advances in Prostaglandin, Thromboxane, and Leukotriene Research, Vol 19. B. Samuelsson, P. Y.-K. Wong, and F. F. Sun, editors. Raven Press Ltd.. New York. 454-457.
33. Bowden, D. H., and I. Y. R. Adamson. 1980. Role of monocytes and interstitial cells in the generation of alveolar macrophages. I. Lab. Invest. 42:511-517.
34. Adamson, I. Y. R., and D. H. Bowden. 1980. Role of monocytes and interstitial cells in the generation of alveolar macrophages, II Lab. Invest. 42:518-524.
35. Thomas, E. D., R. E. Ramberg, and G. E. Sale. 1976. Direct evidence for a bone marrow origin of the alveolar macrophage in man. Science (Wash. DC). 192:1016-1018.
36. Rinehart, J. J., A. Wuest, and G. A. Ackerman. 1982. Corticosteroid alteration of human monocyte to macrophage differentiation. J. Immunol. 129:1436-1440.
37. Newman, S. L., J. E. Henson, and P. M. Henson. 1982. Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J. Exp. Med. 156:430-442.
38. Stevenson, H. C., P. Katz, D. G. Wright, T. J. Contreras, J. F. Jemioneky, V. M. Hartwig, W. J. Fler, and A. S. Fauci. 1981. Human blood monocytes: characterization of negatively selected human monocytes and their suspension cell culture derivatives. Scand. J. Immunol. 14:243-256.
39. Kemmerich, B., R. H. Rossing, and J. E. Pennington. 1987. Comparative oxidative microbicidal activity of human blood monocytes and alveolar macrophages and activation by gamma interferon. Am. Rev. Respir. Dis. 136:266-270.
40. Bigby, T. D., and M. J. Holtzman. 1987. Enhanced 5-lipoxygenase activity in lung macrophages compared to monocytes from normal subjects. J. Immunol 138:1546-1550.
41. 2 and dexamethasone. Am. J. Respir. Cell Mol. Biol. 6:75-81.
42. Rennard, S. I., J. Moss, J. Oberpriller, B. Horn, L. Stier, T. Ozaki, and R. G. Crystal. 1983. Fibroblasts: important producers and targets of inflammatory prostaglandins in the lungs. Chest. 83(5):92S-93S.
43. 2 production in resting macrophages. Biochein. Biophys. Res. Comm. 136:94-101.
44. Goerig. M., A. J. R. Habenicht, W. Zeh, P. Salbach. B. Kommerell, D. E. R. Rothe, W. Nastainczyk, and J. A. Glomset. 1988. Evidence for coordinate, selective regulation of eicosanoid synthesis in platelet-derived growth factor-stimulated 3T3 fibroblasts and in HL-60 cells induced to differentiate into macrophages or neutrophils. J. Biol. Chem. 263:19384-19391.
45. Baiter, M., G. Toews, and M. Peters-Golden. 1989. Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages. J. Immunol. 142:602-608.
46. v-src-transformed 3T3 fibroblasts. Proc. Natl. Acad. Sci. USA. 87:3373-3377.
47. 1, interleukin 1β, and tumor necrosis factor α. J. Biol. Chem. 267:10816-10822.
48. Xie, W., D. L. Robertson, and D. L. Simmons. 1992. Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs. Drug Devel. Res. 25:249-265.
49. Maier, J. A. M., T. Hla, and T. Maciag. 1990. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J. Biol. Chem. 265:10805-10808.
50. Xie, W., J. G. Chipman, D. L. Robertson, R. L. Erikson, and D. L. Simmons. 1991. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA. 88:2692-2696.
51. O'Bannion, M. K., V. D. Winn, and D. A. Young. 1992. cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc. Natl. Acad. Sci. USA. 89:4888-4892.
52. DeWitt, D. L., E. A. El-Harith, and W. L. Smith. 1989. Molecular cloning of prostaglandin G/H synthase. In Advances in Prostaglandin, Thromboxane, and Leukotriene Research, Vol. 19. B. Samuelsson, P. Y.-K. Wong, and F. F. Sun, editors. Raven Press Ltd., New York. 454-457.