메뉴 건너뛰기




Volumn 655, Issue 1-2, 1994, Pages 91-96

Kynurenate is neuroprotective following experimental brain injury in the rat

Author keywords

Excitotoxicity; Head injury pathology; Hippocampus; Kynurenate; Neuroprotection; NMDA antagonist

Indexed keywords

GLUTAMATE RECEPTOR ANTAGONIST; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 0028105981     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(94)91601-2     Document Type: Article
Times cited : (74)

References (52)
  • 1
    • 0022530453 scopus 로고
    • Progress review: hypoglycemic brain damage
    • (1986) Stroke , vol.17 , pp. 699-708
    • Auer1
  • 2
    • 0025763082 scopus 로고
    • An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo
    • (1991) Neuroscience , vol.42 , pp. 387-395
    • Bakker1    Foster2
  • 3
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentration of glutamate and aspartate in rat hippocampus during transient ischemia monitored by intracerebral microdialysis
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Beneviste1    Drejer2    Schousboe3    Diemer4
  • 4
    • 0024544716 scopus 로고
    • Kynurenic acid inhibits the activation of kainic and N-methyl-d-aspartic acid-sensitive ionotropic receptors by a different mechanism
    • (1989) Neuropharmacology , vol.28 , pp. 453-457
    • Bertolini1    Vicini2    Costa3
  • 5
    • 0023809607 scopus 로고
    • Kynurenate and FG9041 have both competitive and noncompetitive antagonist actions at excitatory amino acid receptors
    • (1988) Eur. J. Pharmacol. , vol.151 , pp. 313-315
    • Birch1    Grossman2    Hayes3
  • 6
    • 0025012714 scopus 로고
    • Hypothermia but not the N-methyl-d-aspartate, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia
    • (1990) J. Neurosci. , vol.10 , pp. 311-316
    • Buchan1    Pulsinelli2
  • 7
    • 0024093449 scopus 로고
    • Glutamate toxicity and diseases of the nervous system
    • (1988) Neuron , vol.1 , pp. 623-624
    • Choi1
  • 11
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • (1989) Science , vol.244 , pp. 780-800
    • Faden1    Demediuk2    Panter3    Vink4
  • 14
    • 0026518645 scopus 로고
    • Neurotransmitter mediated mechanisms of traumatic brain injury: Acetylcholine and excitatory amino acids
    • (1992) J. Neurotrauma , vol.9 , Issue.1 S , pp. 173-187
    • Hayes1    Jenkins2    Lyeth3
  • 16
    • 0024518502 scopus 로고
    • Indole-2-carboxylic acid: a competitive antagonist of potentiation by glycine at the NMDA receptor
    • (1989) Science , vol.243 , pp. 1611-1613
    • Heutner1
  • 21
    • 0025885342 scopus 로고
    • Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose
    • (1991) Brain Res. , vol.554 , pp. 344-347
    • Kaku1    Goldberg2    Choi3
  • 22
    • 0025242563 scopus 로고
    • Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury
    • (1990) J. Neurosurg. , vol.73 , pp. 889-900
    • Katayama1    Becker2    Tamura3    Hovda4
  • 25
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • (1982) Brain Res. , vol.239 , pp. 57-69
    • Kirino1
  • 26
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • (1988) Science , vol.241 , pp. 835-837
    • Kleckner1    Dingledine2
  • 27
    • 0026488694 scopus 로고
    • Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head traum and disorders of the hippocampus
    • (1992) J. Neurosci. , vol.12 , pp. 4846-4853
    • Lowenstein1    Thomas2    Smith3    McIntosh4
  • 30
    • 0024990864 scopus 로고
    • Effect of noncompetitive blockade of N-methyl-d-aspartate receptors on the neurochemical sequelae of experimental brain injury
    • (1990) J. Neurochem. , vol.55 , pp. 1170-1179
    • McIntosh1    Vink2    Soares3    Hayes4    Simon5
  • 32
    • 0021912595 scopus 로고
    • Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters
    • (1985) Clin. Sci. , vol.68 , pp. 113-121
    • Meldrum1
  • 33
  • 35
    • 0025914187 scopus 로고
    • Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina
    • (1991) Exp. Neurol. , vol.113 , pp. 10-17
    • Mossinger1    Price2    Bai3    Xiao4    Wozniak5    Olney6
  • 37
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney1    Labruyere2    Price3
  • 41
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • (1986) Ann. Neurol. , vol.19 , pp. 105-111
    • Rothman1    Olney2
  • 48
    • 0027132491 scopus 로고
    • Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid, on behavioral and neurochemical outcome following experimental brain injury
    • (1993) J. Neurosci. , vol.13 , pp. 5383-5392
    • Smith1    Okiyama2    Thomas3    McIntosh4
  • 49
    • 0026847039 scopus 로고
    • Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans
    • (1992) Psychol. Rev. , vol.99 , pp. 5821-5841
    • Squire1
  • 50
    • 0026849958 scopus 로고
    • Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network
    • (1992) Hippocampus , vol.2 , pp. 189-199
    • Treves1    Rolls2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.